I. Fernández-Ruíz

发表

Device therapy: A robotic heart sleeve to keep the beat

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Translocated LPS Might Cause Endotoxin Tolerance in Circulating Monocytes of Cystic Fibrosis Patients

C. del Fresno, E. López-Collazo, R. del Campo, 2011, PloS one.

Potent Phagocytic Activity with Impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients1

T. Kajiji, C. del Fresno, E. López-Collazo, 2009, The Journal of Immunology.

Mitochondrial DAMPs Induce Endotoxin Tolerance in Human Monocytes: An Observation in Patients with Myocardial Infarction

J. López-Sendón, L. Boscá, E. López-Collazo, 2014, PloS one.

Atherosclerosis: Should we redefine the 'normal' LDL-cholesterol range?

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

High relapse rate after HF medication withdrawal

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

The search for an effective HFpEF treatment continues

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Flu vaccination shortly after MI reduces the risk of complications

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Systolic and diastolic hypertension independently predict CVD risk

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

T cells in the gut promote CVD and slow metabolism

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Heart failure: No effect of ularitide in heart failure outcomes

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Dyslipidaemia: FH genes, beyond LDL-C, predict CAD

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

GRK5 linked to cardiac dysfunction and leukocyte recruitment after MI

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Diabetes: Sacubitril/valsartan improves glycaemic control

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Dissecting the benefits of sacubitril–valsartan for heart failure

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Mechanisms of sacubitril–valsartan benefit in HFrEF

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Monocytes from Cystic Fibrosis Patients Are Locked in an LPS Tolerance State: Down-Regulation of TREM-1 as Putative Underlying Mechanism

Felipe García, C. del Fresno, E. López-Collazo, 2008, PloS one.

Microthrombi cause cardiac injury in COVID-19

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Impaired antigen presentation and potent phagocytic activity identifying tumor-tolerant human monocytes.

S. Biswas, E. López-Collazo, C. Fresno, 2011, Biochemical and biophysical research communications.

Aspirin for primary prevention of CVD: a matter of balance

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Dietary supplements undergo VITAL test

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Promising biomarker for the early, non-invasive diagnosis of myocarditis

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Diabetes: Further insights into SGLT2 inhibitors

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Coronary artery disease: Urbanization is a risk factor for CAD

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Cardiomyopathy: Takotsubo has long-lasting functional consequences

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Inflammation linked to Takotsubo

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

AKCEA-APO(a)-LRx lowers Lp(a) levels in patients

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Milestone 7: A breakthrough for out-of-hospital treatment of thrombosis.

I. Fernández-Ruíz, 2017, Nature reviews. Cardiology.

Dapagliflozin improves outcomes in HFmrEF and HFpEF

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

Tailoring antithrombotic strategies for high-risk AF populations

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

LDL quality influences CAD progression

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Coronary artery disease: CABG surgery or PCI for left main CAD?

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Imaging: Pacemakers, ICDs, and MRI

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Arrhythmias: Noninvasive radioablation for VT

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Immune system and cardiovascular disease

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

Renewed hopes for renal denervation in hypertension

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Neuroendocrine effects of an acute dose of δ9-tetrahydrocannabinol : changes in hypothalamic biogenic amines and anterior pituitary hormone secretion

J. Ramos, Medardo Hernández, M. Navarro, 1992 .

Machine learning predicts risk in ACS

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Differential lipid metabolism in monocytes and macrophages: influence of cholesterol loading[S]

S. Parthasarathy, P. Puchalska, I. Fernández-Ruíz, 2016, Journal of Lipid Research.

Inflammation: NETs are involved in AAA

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients

T. Kajiji, C. del Fresno, E. López-Collazo, 2009, The Journal of Immunology.

Atherosclerosis: A new role for lncRNAs in atherosclerosis

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Persistent competition among stem cells and their daughters in the Drosophila ovary germline niche

Eduardo Moreno, J. Poyatos, Jesús M. López-Gay, 2009, Development.

NFκB2/p100 Is a Key Factor for Endotoxin Tolerance in Human Monocytes: A Demonstration Using Primary Human Monocytes from Patients with Sepsis

M. Fresno, L. Boscá, C. del Fresno, 2014, The Journal of Immunology.

Alcohol abstinence reduces AF recurrence

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Immunology: Surprising role of cardiac macrophages in heart electrical conduction

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Cilia defects linked to mitral valve prolapse

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Coronary artery disease: New polygenic risk score improves prediction of CHD

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM‐1‐PI3K‐NF‐κB pathway

S. Biswas, E. López-Collazo, C. Fresno, 2012, Journal of leukocyte biology.

Metalloproteinases Shed TREM-1 Ectodomain from Lipopolysaccharide-Stimulated Human Monocytes1

Felipe García, C. del Fresno, E. López-Collazo, 2007, The Journal of Immunology.

Base editing of CaMKIIδ shows promise as cardiac therapy.

I. Fernández-Ruíz, 2023, Nature reviews. Cardiology.

Monocytes Lipopolysaccharide-Stimulated Human Ectodomain from Metalloproteinases Shed TREM-1 and

E. López-Collazo, C. Fresno, P. Fuentes-Prior, 2007 .

Very high HDL-C levels are associated with higher mortality in patients with CAD

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

HDAC9 linked to aortic calcification

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Prevention: The healthy diet — fruits, vegetables, legumes, and fats

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Drone delivery of defibrillators for sudden cardiac arrest could shorten response times

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Dyslipidaemia: Promising results with siRNA against PCSK9

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

GPR146 is a potential new therapeutic target for lipid lowering

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Atherosclerosis--do we know enough already to prevent it?

S. Parthasarathy, A. Riad, I. Fernández-Ruíz, 2016, Current opinion in pharmacology.

Intensive blood pressure control benefits older patients

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

CD16 Regulates TRIF-Dependent TLR4 Response in Human Monocytes and Their Subsets

S. Wong, S. Biswas, T. Kajiji, 2012, The Journal of Immunology.

Subsets Response in Human Monocytes and Their CD16 Regulates TRIF-Dependent TLR4

S. Wong, S. Biswas, T. Kajiji, 2012 .

Rebalancing the pyruvate–lactate axis to treat heart failure

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Drug-coated balloons — another option for small-vessel disease

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Corrections

S. Biswas, T. Kajiji, C. Lamare, 1980, The Lancet Neurology.

Role of rivaroxaban after TAVI

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Growth and development: Poly(A) tail-based regulation of cardiac hypertrophy

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Dyslipidaemia: Is CETP inhibition a viable therapeutic strategy?

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Cardiomyopathies: The happy heart syndrome

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

RAAS inhibitors do not increase the risk of COVID-19

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Vascular disease: Ticagrelor not superior to clopidogrel for PAD

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Stratifying the effects of SGLT2i

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Rejuvenating cardiomyocytes facilitates heart regeneration

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Artificial intelligence to improve the diagnosis of cardiovascular diseases

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

ACE2 level as a marker of CVD

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Unravelling the atheroprotective mechanisms of LDL immunization

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Macropinocytosis promotes foam cell formation and atherosclerosis

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

Metabolism: Calorie restriction for healthy ageing

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Thrombosis: Rivaroxaban, a cost-effective alternative for SVT?

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Stem cells: Cell therapy improves outcomes in heart failure

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

Dyslipidaemia: No effect of PCSK9 inhibitors on cognitive function

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Acute coronary syndromes: Microbial-dependent TMAO as a prognostic marker in ACS

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Heart failure: No early benefits of adjunct therapy with tolvaptan for acute heart failure

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Risk factors: Air pollution accelerates progression of atherosclerosis

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

Statins promote efferocytosis in atherosclerotic plaques

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

Novel genetic variant linked with high LDL-C levels

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

No benefit of initial invasive strategy for managing CAD in advanced CKD

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Gene enhancer variation modifies cardiomyopathy

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Decoding a major CAD risk locus

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Genetics: ANGPTL3 deficiency protects from CAD

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Novel cardioprotective lymphatic signal identified

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Boosting stem cell vascular regenerative capacity

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Milestone 5: High-dose heparin for secondary prevention.

I. Fernández-Ruíz, 2017, Nature reviews. Cardiology.

Prime time for ticagrelor monotherapy

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Breakthrough in heart xenotransplantation

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Persistent competition among stem cells and their daughters in the Drosophila ovary germline niche

J. F. Poyatos, Jesús M. López-Gay, Marta Portela, 2009, Development.

Very high HDL-C levels are associated with higher mortality in patients with CAD

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients

T. Kajiji, C. del Fresno, E. López-Collazo, 1990, The Journal of Immunology.

Surgery: Neutral results for levosimendan in cardiac surgery

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Subcutaneous ICD noninferior to transvenous ICD

I. Fernández-Ruíz, 2020, Nature Reviews Cardiology.

Glucocorticoid receptor inhibition promotes cardiac repair after MI

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

Disrupting a cell-specific miRNA–CXCR4 interaction is atheroprotective in mice

I. Fernández-Ruíz, 2023, Nature reviews. Cardiology.

Risk factors: Aircraft noise impairs vascular function

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

NIRS to identify vulnerable plaques

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Pharmacotherapy: Angiotensin II — a new tool in vasodilatory shock

I. Fernández-Ruíz, 2017, Nature Reviews Cardiology.

Targeting PCSK9 to reduce residual risk in ACS

Alexandra Le Bras, I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

α-Myosin-specific CD8^+ T cells drive ICI-related myocarditis

I. Fernández-Ruíz, 2022, Nature Reviews Cardiology.

Milestone 12: In search of better therapies to prevent device-induced thrombosis.

I. Fernández-Ruíz, 2017, Nature reviews. Cardiology.

Modulating the gut microbiota with dietary interventions to protect against cardiometabolic disease

I. Fernández-Ruíz, 2021, Nature Reviews Cardiology.

Thrombosis: Gut microbes modulate platelet function and thrombosis risk

I. Fernández-Ruíz, 2016, Nature Reviews Cardiology.

Whole-genome sequencing for HCM screening

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Novel vasodilatory factor identified

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.

Dietary supplements undergo VITAL test

I. Fernández-Ruíz, 2018, Nature Reviews Cardiology.

Exercise protects against cardiovascular disease by modulating immune cell supply

I. Fernández-Ruíz, 2019, Nature Reviews Cardiology.