A. B. Jefferson

发表

Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.

E. Altmann, U. Hassiepen, M. Renatus, 2017, Angewandte Chemie.

Properties of Type II Inositol Polyphosphate 5-Phosphatase (*)

P. Majerus, A. B. Jefferson, 1995, The Journal of Biological Chemistry.

AKT Kinase and Hsp90 Inhibitors as Novel Anti-cancer Therapeutics

Xiaodong Lin, Zhenhai Gao, T. Machajewski, 2005 .

Sphingosine inhibits calmodulin-dependent enzymes.

H. Schulman, A. B. Jefferson, 1988, The Journal of biological chemistry.

Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers

M. Lindvall, E. Venetsanakos, Jiong Lan, 2014, Molecular Cancer Research.

PLK1 as a potential drug target in cancer therapy

Yifa Zhou, Haishan Wang, Xukun Wang, 2004 .

Signaling Inositol Polyphosphate-5-phosphatase

D. Pot, P. Majerus, L. Williams, 1997, The Journal of Biological Chemistry.

Design and synthesis of potent RSK inhibitors.

M. Lindvall, Abran Q. Costales, Michelle Mathur, 2018, Bioorganic & medicinal chemistry letters.

Thrombin-stimulated immunoprecipitation of phosphatidylinositol 3-kinase from human platelets.

J. Brugge, P. Majerus, C. Mitchell, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies.

E. Fang, Sylvia Ma, J. Murray, 2006, Bioorganic & medicinal chemistry letters.

Targeted inhibition of the COP9 signalosome for treatment of cancer

E. Altmann, U. Hassiepen, M. Renatus, 2016, Nature Communications.

A Novel Phosphatidylinositol-3,4,5-trisphosphate 5-Phosphatase Associates with the Interleukin-3 Receptor*

P. Majerus, G. Krystal, F. Norris, 1996, The Journal of Biological Chemistry.

Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase: broad substrate specificity and multifunctional potential in diverse tissues.

H. Schulman, J. Kuret, K. Spitzer, 1985, Biochemistry.

Mutation of the conserved domains of two inositol polyphosphate 5-phosphatases.

P. Majerus, A. B. Jefferson, 1996, Biochemistry.

Cloning and expression of human 75-kDa inositol polyphosphate-5-phosphatase.

P. Majerus, C. Mitchell, T. Ross, 1991, The Journal of biological chemistry.

2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors.

M. Lindvall, A. Jefferson, Abran Q. Costales, 2014, Bioorganic & medicinal chemistry letters.

Ca2+/calmodulin kinase is activated by the phosphatidylinositol signaling pathway and becomes Ca2(+)-independent in PC12 cells.

H. Schulman, A. B. Jefferson, M. MacNicol, 1990, The Journal of biological chemistry.

Activation of multifunctional Ca2+/calmodulin-dependent protein kinase in GH3 cells.

H. Schulman, A. B. Jefferson, S. Travis, 1991, The Journal of biological chemistry.

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.

P. Majerus, G. Krystal, A. Jefferson, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/β-catenin signaling is activated in human colon tumors

M. Wiesmann, W. Fantl, J. Escobedo, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Loss of PTEN facilitates HIF-1-mediated gene expression.

A. Koong, F. Kaper, A. Giaccia, 2000, Genes & development.

Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

D. Pot, F. Masiarz, P. Majerus, 1996, Current Biology.

The protein deficient in Lowe syndrome is a phosphatidylinositol-4,5-bisphosphate 5-phosphatase.

P. Majerus, X. Zhang, A. B. Jefferson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Recent insights in phosphatidylinositol signaling

P. Majerus, T. Ross, V. Bansal, 1990, Cell.

The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.

J. Krosl, P. Majerus, A. Miyajima, 1997, Leukemia.

Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain

A. Klippel, A. Jefferson, L. Williams, 1998, Oncogene.

Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers

M. Lindvall, E. Venetsanakos, Jiong Lan, 2014, Molecular Cancer Research.