Sven H. Schmidt

Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2

Susan S. Taylor, S. Knapp, E. Komives, 2020, Proceedings of the National Academy of Sciences.

The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain

Susan S. Taylor, Mark Ellisman, A. Kornev, 2019, Proceedings of the National Academy of Sciences.

Nanobodies as allosteric modulators of Parkinson’s disease–associated LRRK2

S. Knapp, E. Pardon, J. Steyaert, 2021, bioRxiv.

Molecular Basis for Ser/Thr Specificity in PKA Signaling

F. Herberg, Daniela Bertinetti, Matthias J Knape, 2020, Cells.

Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2

F. Herberg, Daniela Bertinetti, S. Pautz, 2020, Frontiers in Neuroscience.

Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.

B. Sankaran, Choel Kim, J. J. Kim, 2017, The Biochemical journal.

Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery

Susan S. Taylor, S. Knapp, F. Herberg, 2020, Frontiers in Molecular Neuroscience.

Targeted Inhibition of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 with a Constrained J Domain-Derived Disruptor Peptide.

E. Kennedy, D. Peterson, F. Herberg, 2019, ACS infectious diseases.

Two helices control the dynamic crosstalk between the catalytic domains of LRRK2

Susan S. Taylor, S. Knapp, Jian Wu, 2021, bioRxiv.