Nan Wang

发表

ABC Transporters, Cholesterol Efflux, and Implications for Cardiovascular Diseases.

M. Westerterp, Nan Wang, 2020, Advances in experimental medicine and biology.

Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis

A. Tall, O. Soehnlein, Yong-Guang Yang, 2022, The Journal of clinical investigation.

Reduced VLDL clearance in Apoe−/−Npc1−/− mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels

A. Tall, C. Welch, M. Ishibashi, 2010, Journal of Lipid Research.

Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2V617F Mice

A. Tall, R. Levine, O. Soehnlein, 2018, Circulation research.

ATP-binding Cassette Transporter A1 (ABCA1) Functions as a Cholesterol Efflux Regulatory Protein*

A. Tall, C. Thiele, D. Silver, 2001, The Journal of Biological Chemistry.

ATP-Binding Cassette Transporter G1 and High-Density Lipoprotein Promote Endothelial NO Synthesis Through a Decrease in the Interaction of Caveolin-1 and Endothelial NO Synthase

A. Tall, C. Fernández-Hernando, W. Sessa, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Inhibition of JAK2 Suppresses Myelopoiesis and Atherosclerosis in Apoe−/− Mice

A. Tall, R. Levine, Wei Wang, 2020, Cardiovascular Drugs and Therapy.

A New Approach to PCSK9 Therapeutics.

A. Tall, Nan Wang, 2017, Circulation research.

A New Approach to PCSK9 Therapeutics.

A. Tall, Nan Wang, 2017, Circulation Research.

Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein

A. Tall, G. Gusarova, E. Papapetrou, 2021, Scientific Reports.

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL Published, JLR Papers in Press, October 24, 2007.

A. Tall, Takafumi Senokuchi, L. Yvan-Charvet, 2008, Journal of Lipid Research.

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses.

A. Tall, L. Yvan-Charvet, Nan Wang, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Role of HDL , ABCA 1 , and ABCG 1 Transporters in Cholesterol Efflux and Immune Responses

S. Hazen, A. Tall, L. Yvan-Charvet, 2009 .

Decreased Atherosclerosis in Heterozygous Low Density Lipoprotein Receptor-deficient Mice Expressing the Scavenger Receptor BI Transgene*

A. Tall, Takeshi Arai, Nan Wang, 1999, The Journal of Biological Chemistry.

HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway.

A. Tall, Wengen Chen, Xian-cheng Jiang, 2006, The Journal of clinical investigation.

Scavenger Receptor BI (SR-BI) Is Up-regulated in Adrenal Gland in Apolipoprotein A-I and Hepatic Lipase Knock-out Mice as a Response to Depletion of Cholesterol Stores

A. Tall, J. Breslow, Wei Wang, 1996, The Journal of Biological Chemistry.

The Failure of Torcetrapib

A. Tall, L. Yvan-Charvet, Nan Wang, 2007 .

Regulation and mechanisms of macrophage cholesterol efflux.

A. Tall, P. Costet, Nan Wang, 2002, The Journal of clinical investigation.

Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis

M. Reilly, M. Makishima, A. Tall, 2022, Arteriosclerosis, thrombosis, and vascular biology.

High-density lipoprotein extinguishes fire in fat.

Nan Wang, 2013, Circulation research.

A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.

P. Linsel-Nitschke, A. Tall, Wengen Chen, 2003, The Journal of clinical investigation.

Potential role of ABCA7 in cellular lipid efflux to apoA-I Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400247-JLR200

P. Linsel-Nitschke, A. Tall, Jing Shan, 2005, Journal of Lipid Research.

Hepatic Scavenger Receptor BI Promotes Rapid Clearance of High Density Lipoprotein Free Cholesterol and Its Transport into Bile*

A. Tall, J. Breslow, D. Huszar, 1999, The Journal of Biological Chemistry.

7. Lipid transfer proteins and receptors in HDL metabolism

T. Arai, A. Tall, D. Silver, 1999 .

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.

A. Tall, C. Welch, I. Goldberg, 2008, The Journal of clinical investigation.

Mitochondrial Oxidative Stress Promotes Atherosclerosis and Neutrophil Extracellular Traps in Aged Mice

A. Tall, I. Tabas, Wei Wang, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis

K. Moore, M. Reilly, A. Tall, 2018, Circulation.

Exome-wide association study of plasma lipids in >300,000 individuals

Raquel S. Sevilla, Dajiang J. Liu, Chad A. Cowan, 2017, Nature Genetics.

Effects of Enalapril on TLR2/NF-κB Signaling Pathway and Inflammatory Factors in Rabbits with Chronic Heart Failure

Yanping Tang, Nan Wang, Zelin Xu, 2021, Evidence-based complementary and alternative medicine : eCAM.

The roles of different pathways in the release of cholesterol from macrophages Published, JLR Papers in Press, August 29, 2007.

D. Rader, M. Adorni, F. Zimetti, 2007, Journal of Lipid Research.

Deficiency of ATP binding cassette transporter b6 in megakaryocyte progenitors accelerates atherosclerosis in mice

A. Murphy, J. Schuetz, C. Welch, 2014 .

Results Suppression of Myeloid Cell mitoOS Protects Against Atherosclerosis and Reduces Myeloid Cell Accumulation in Aged Mice

A. Tall, I. Tabas, Ying Wang, 2017 .

Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

A. Tall, R. Levine, A. Murphy, 2013, Nature Medicine.

A PEST Deletion Mutant of ABCA1 Shows Impaired Internalization and Defective Cholesterol Efflux from Late Endosomes*

A. Tall, Wengen Chen, Nan Wang, 2005, Journal of Biological Chemistry.

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

A. Tall, D. Lan, Wengen Chen, 2004, Proceedings of the National Academy of Sciences of the United States of America.

ATP-binding cassette transporters, atherosclerosis, and inflammation.

A. Tall, A. Murphy, M. Westerterp, 2014, Circulation research.

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

A. Tall, H. Snoeck, C. Welch, 2010, Science.

Specific Binding of ApoA-I, Enhanced Cholesterol Efflux, and Altered Plasma Membrane Morphology in Cells Expressing ABC1*

A. Tall, D. Silver, P. Costet, 2000, The Journal of Biological Chemistry.

β-adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines.

N. Wang, Kai Xu, H. Sabbah, 2011, Cardiovascular research.

Increased Inflammatory Gene Expression in ABC Transporter–Deficient Macrophages: Free Cholesterol Accumulation, Increased Signaling via Toll-Like Receptors, and Neutrophil Infiltration of Atherosclerotic Lesions

A. Tall, C. Welch, M. Lamkanfi, 2008, Circulation.

LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis.

A. Tall, R. Levine, C. Welch, 2016, Circulation research.

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

O. Abdel-Wahab, A. Tall, R. Levine, 2020, Cell reports.

HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis.

A. Tall, L. Yvan-Charvet, N. Terasaka, 2008, Cell metabolism.

Scavenger Receptor BI Promotes High Density Lipoprotein-mediated Cellular Cholesterol Efflux*

Yong Ji, Nan Wang, A. Tall, 1997, The Journal of Biological Chemistry.

Interleukin 8 Is Induced by Cholesterol Loading of Macrophages and Expressed by Macrophage Foam Cells in Human Atheroma (*)

A. Tall, I. Tabas, S. Ravalli, 1996, The Journal of Biological Chemistry.

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

P. Linsel-Nitschke, A. Tall, W. Janssen, 2006, The Journal of cell biology.

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

P. Libby, M. Reilly, B. Ebert, 2021, Nature.

Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency

A. Tall, P. Natarajan, A. Bick, 2021, Circulation.

The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of β-amyloid precursor protein Published, JLR Papers in Press, February 10, 2007.

C. Wellington, R. Demattos, Anna Wilkinson, 2007, Journal of Lipid Research.

The cholesterol transporter ABCG 1 modulates the subcellular distribution and proteolytic processing of b-amyloid precursor protein

C. Wellington, R. Demattos, Anna Wilkinson, 2007 .

Cholesterol in platelet biogenesis and activation.

A. Tall, Nan Wang, 2016, Blood.

ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux*

P. Linsel-Nitschke, A. Tall, N. Wang, 2003, Journal of Biological Chemistry.

Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux

A. Tall, N. Wang, Nan Wang, 2003, Arteriosclerosis, thrombosis, and vascular biology.

ATVB In Focus Role of ABCA1 in Cellular Cholesterol Efflux and Reverse Cholesterol Transport

A. Tall, Nan Wang, 2003 .

Enhanced Megakaryopoiesis and Platelet Activity in Hypercholesterolemic, B6-Ldlr −/−, Cdkn2a-Deficient Mice

A. Tall, C. Welch, Wei Wang, 2016, Circulation. Cardiovascular genetics.

Pegylation of High-Density Lipoprotein Decreases Plasma Clearance and Enhances Antiatherogenic Activity

A. Tall, A. Murphy, S. Funt, 2013, Circulation research.

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

A. Tall, A. Murphy, E. Fisher, 2013, Circulation research.

Liver-specific Overexpression of Scavenger Receptor BI Decreases Levels of Very Low Density Lipoprotein ApoB, Low Density Lipoprotein ApoB, and High Density Lipoprotein in Transgenic Mice*

A. Tall, F. Rinninger, Takeshi Arai, 1998, The Journal of Biological Chemistry.

High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1

A. Tall, N. Wang, L. Yvan-Charvet, 2007, Proceedings of the National Academy of Sciences.

The failure of torcetrapib: was it the molecule or the mechanism?

A. Tall, N. Wang, L. Yvan-Charvet, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.

V. D’Agati, A. Tall, G. Randolph, 2017, Cell metabolism.

IFN- g Potentiates Atherosclerosis in ApoE Knock-out Mice

A. Tall, C. Schindler, Sanjay Gupta, 1997 .

Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques.

A. Tall, K. Bornfeldt, V. Kothari, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Phosphorylation of a Pest Sequence in ABCA1 Promotes Calpain Degradation and Is Reversed by ApoA-I*

A. Tall, Wengen Chen, L. Martinez, 2003, Journal of Biological Chemistry.

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

A. Tall, C. Welch, L. Yvan-Charvet, 2007, The Journal of clinical investigation.

Inhibition of Cholesteryl Ester Transfer Protein by Torcetrapib Modestly Increases Macrophage Cholesterol Efflux to HDL

C. Shear, A. Tall, N. Wang, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors*

A. Tall, M. Phillips, G. Rothblat, 1998, The Journal of Biological Chemistry.

Decreased Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice Transplanted With Abcg1−/− Bone Marrow

A. Tall, C. Welch, N. Wang, 2006, Arteriosclerosis, thrombosis, and vascular biology.

High-Density Lipoproteins, Endothelial Function, and Mendelian Randomization.

A. Tall, N. Wang, M. Westerterp, 2016, Circulation research.

Pivotal Advance: Macrophages become resistant to cholesterol‐induced death after phagocytosis of apoptotic cells

A. Tall, Yankun Li, I. Tabas, 2007, Journal of leukocyte biology.

Deficiency of ATP-Binding Cassette Transporter B6 in Megakaryocyte Progenitors Accelerates Atherosclerosis in Mice

A. Murphy, J. Schuetz, M. Westerterp, 2014, Arteriosclerosis, thrombosis, and vascular biology.

ATP-binding cassette transporters G 1 and G 4 mediate cellular cholesterol efflux to high-density lipoproteins

A. Tall, D. Lan, Wengen Chen, 2004 .

LXR-Induced Redistribution of ABCG1 to Plasma Membrane in Macrophages Enhances Cholesterol Mass Efflux to HDL

A. Tall, N. Wang, F. Matsuura, 2006, Arteriosclerosis, thrombosis, and vascular biology.

High Density Lipoprotein (HDL) Particle Uptake Mediated by Scavenger Receptor Class B Type 1 Results in Selective Sorting of HDL Cholesterol from Protein and Polarized Cholesterol Secretion*

A. Tall, D. Silver, N. Wang, 2001, The Journal of Biological Chemistry.

ATP‐binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

A. Tall, Tae-Wan Kim, N. Wang, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD.

Yuan Zhang, B. Chakraborty, O. Melander, 2017, Journal of molecular and cellular cardiology.

Identification of Small PDZK1-associated Protein, DD96/MAP17, as a Regulator of PDZK1 and Plasma High Density Lipoprotein Levels*

S. Vogel, D. Silver, Nan Wang, 2003, Journal of Biological Chemistry.

Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion

P. Libby, A. Tall, M. Westerterp, 2022, Cardiovascular research.

Bioactive Compound Screen for Pharmacological Enhancers of Apolipoprotein E in Primary Human Astrocytes.

Ronald Realubit, Sungkwon Chung, Charles Karan, 2016, Cell chemical biology.

Blockade of IL-6 signaling alleviates atherosclerosis in Tet2-deficient clonal hematopoiesis

P. Libby, A. Tall, R. Levine, 2023, Nature Cardiovascular Research.

Therapeutic modulation of cellular cholesterol efflux

A. Tall, Nan Wang, 2001, Current atherosclerosis reports.

Interactions between macrophages and oxidized low density lipoprotein in the presence of type I collagen

G. Jürgens, E. Wei, Qi Chen, 1997, BioFactors.

Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis.

A. Tall, O. Soehnlein, Yong-Guang Yang, 2022, The Journal of clinical investigation.

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor.

A. Tall, Y. Luo, P Costet, 2000, The Journal of biological chemistry.

UvA-DARE ( Digital Academic Repository ) HDL cholesterol : atherosclerosis and beyond

A. Tall, A. Murphy, M. Westerterp, 2013 .

Is it time to modify the reverse cholesterol transport model?

A. Tall, P. Mucksavage, Nan Wang, 2001, The Journal of clinical investigation.

Tangier disease as a test of the reverse cholesterol transport hypothesis.

A. Tall, Nan Wang, N. Wang, 2000, The Journal of clinical investigation.

Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry

Emily C. O'Brien, J. Knowles, D. Rader, 2016, Circulation. Cardiovascular genetics.

Clonal hematopoiesis and ischemic stroke.

A. Tall, Nan Wang, 2023, Blood.

Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol.

A. Tall, D. Huszar, J. Deeds, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A. Tall, C. Welch, M. Lamkanfi, 2008, Circulation.

ATP-binding cassette transporters, atherosclerosis, and inflammation.

A. Tall, A. Murphy, M. Westerterp, 2014, Circulation research.

Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism.

A. Tall, X. Jiang, R. Ramakrishnan, 1999, Arteriosclerosis, thrombosis, and vascular biology.

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.

A. Tall, C. Welch, I. Goldberg, 2008, The Journal of clinical investigation.

ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux*

P. Linsel-Nitschke, A. Tall, D. Lan, 2003, Journal of Biological Chemistry.

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

P. Linsel-Nitschke, A. Tall, C. Qin, 2006, The Journal of cell biology.

Cell Surface Localization of ABCG1 Does Not Require LXR Activation

A. Tall, M. Ranalletta, Nan Wang, 2006 .