Omar Robles

发表

A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.

Jeffrey W. Smith, J. Sacchettini, S. Sieber, 2017, Bioorganic & medicinal chemistry.

Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.

D. Pookot, R. Sreenivasan, A. Ng, 2022, Journal of medicinal chemistry.

Convergent synthesis of fostriecin via selective alkene couplings and regioselective asymmetric dihydroxylation.

F. McDonald, Omar Robles, 2009, Organic letters.

Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment.

D. Pookot, Abood Okal, P. Kassner, 2019, Journal of medicinal chemistry.

Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as Single Agent and in Combination with Checkpoint Inhibitors.

P. Kassner, G. Cutler, M. Zibinsky, 2020, Journal of medicinal chemistry.

Chemo- and site-selective derivatizations of natural products enabling biological studies.

D. Romo, Omar Robles, 2014, Natural product reports.

Concise synthesis of the isothiourea organocatalysts homobenzotetramisole and derivatives.

D. Romo, Omar Robles, Beatrice Ranieri, 2013, The Journal of organic chemistry.

Modular synthesis of the C9-C27 degradation product of aflastatin A via alkyne-epoxide cross-couplings.

F. McDonald, Omar Robles, 2008, Organic letters.

Cyclopropanations of olefin-containing natural products for simultaneous arming and structure activity studies.

J. Gutiérrez-Uribe, S. Serna-Saldívar, D. Romo, 2012, Organic letters.

Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia

Shuxing Zhang, W. Plunkett, Yuling Chen, 2019, Leukemia.

EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22

P. Kassner, P. Busson, G. Cutler, 2022, PLoS pathogens.

Tumors establish resistance to immunotherapy by regulating Treg recruitment via CCR4

D. Pookot, P. Kassner, G. Cutler, 2020, Journal for ImmunoTherapy of Cancer.

Intrahepática gestacional Gestational Intrahepatic Cholestasis

Omar Robles, 2020 .

Discovery of a Potent and Selective CCR4 Antagonist That Inhibits Treg Trafficking into the Tumor Microenvironment.

Abood Okal, P. Kassner, G. Cutler, 2019, Journal of medicinal chemistry.