Kohei Hoshikawa

Simple LC-MS/MS method using core-shell ODS microparticles for the simultaneous quantitation of edoxaban and its major metabolites in human plasma.

Saki Ariizumi, Yuichiro Maekawa, M. Saotome, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

An enantiomeric quantitative LC-MS/MS method for tolvaptan and its monohydroxylates in human plasma using a reversed-phase separation procedure.

Yuichiro Maekawa, M. Saotome, T. Naito, 2019, Journal of pharmaceutical and biomedical analysis.

Stereoselective interaction of tolvaptan with amiodarone under racemic metabolic impact by CYP3A5 genotypes in heart failure patients

M. Saotome, T. Naito, J. Kawakami, 2022, European Journal of Clinical Pharmacology.

Impact of CYP3A5 genotype on tolvaptan pharmacokinetics and their relationships with endogenous markers of CYP3A activity and serum sodium level in heart failure patients

Yuichiro Maekawa, M. Saotome, T. Naito, 2020, Basic & clinical pharmacology & toxicology.

Validated liquid chromatography coupled to tandem mass spectrometry method for simultaneous quantitation of tolvaptan and its five major metabolites in human plasma

Yuichiro Maekawa, M. Saotome, T. Naito, 2019, Annals of clinical biochemistry.