Zhong-Zhen Zhou

发表

Selective Copper–N-Heterocyclic Carbene (Copper-NHC)-Catalyzed Aerobic Cleavage of β-1 Lignin Models to Aldehydes

Chao‐Jun Li, Mingxin Liu, Zhong-Zhen Zhou, 2017 .

Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect.

Menghua Liu, Chang Huang, Jia-Yin Guo, 2019, European journal of medicinal chemistry.

Discovery of 2‐(3,4‐dialkoxyphenyl)‐2‐(substituted pyridazin‐3‐yl)acetonitriles as phosphodiesterase 4 inhibitors with anti‐neuroinflammation potential based on three‐dimensional quantitative structure–activity relationship study

Chang Huang, Zhong-Zhen Zhou, Lv Tang, 2018, Chemical biology & drug design.

Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition

Wenhua Zheng, Zhong-Zhen Zhou, Hai-Tao Wang, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease.

Jie Liu, Kai-Wen Feng, Zhong-Zhen Zhou, 2022, European journal of medicinal chemistry.

Synthesis, selective cytotoxicities and probable mechanism of action of 7-methoxy-3-arylflavone-8-acetic acids.

Wen-Hua Chen, Chun-ping Gu, Le Yu, 2014, Bioorganic & medicinal chemistry.

One-pot synthesis and antiproliferative activity of novel 2,4-diaminopyrimidine derivatives bearing piperidine and piperazine moieties.

Hai-Kui Yang, Wen-wei You, Meng-Jin Hu, 2014, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of substituted aminopyridazin-3(2H)-ones as G0/G1-phase arresting agents with apoptosis-inducing activities.

Zhong-Zhen Zhou, Jiang-Ping Xu, Hai-Tao Wang, 2017, European journal of medicinal chemistry.

Simple and Clean Photo-induced Methylation of Heteroarenes with MeOH

Chao‐Jun Li, Xiaobo Yang, Wenbo Liu, 2017 .

Discovery of Dihydropyrrol-2-ones as Novel G0/G1-Phase Arresting Agents Inducing Apoptosis

Qiuhua Zhu, Hui Liao, Shaoyu Wu, 2019, ACS omega.

Synthesis, hydrolytic DNA-cleaving activities and cytotoxicities of EDTA analogue-tethered pyrrole-polyamide dimer-based Ce(IV) complexes.

Cheng Dong, Wen-Hua Chen, Bo-Chi Wang, 2014, European journal of medicinal chemistry.

Efficient One-Pot Synthesis of 3-Amino-7-azaindoles Under Microwave Irradiation

Zhi-Hong Jiang, Hai-Kui Yang, Wen-wei You, 2014 .

Microwave-Assisted Dieckmann Reaction: Efficient One-Step Synthesis of 2-Aroylbenzofuran-3-ols

Zhi-Hong Jiang, Wen-Hua Chen, Zhong-Zhen Zhou, 2010 .

Synthesis, Biological Evaluation, and Molecular Docking of Arylpyridines as Antiproliferative Agent Targeting Tubulin.

Jie Liu, Zhong-Zhen Zhou, Lv Tang, 2020, ACS medicinal chemistry letters.

Catecholic amides as potential selective phosphodiesterase 4D inhibitors: Design, synthesis, pharmacological evaluation and structure-activity relationships.

Zhong-Zhen Zhou, Jiang-Ping Xu, Xiu-Dong Shi, 2015, Bioorganic & medicinal chemistry.

Synthesis and anticancer activities of 3-arylflavone-8-acetic acid derivatives.

Wen-Hua Chen, Chun-Qiong Zhou, Shu-wen Liu, 2015, European journal of medicinal chemistry.

Silver(I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage.

Chao‐Jun Li, Leiyang Lv, Mingxin Liu, 2018, Angewandte Chemie.

Synthesis and anionophoric activities of dimeric polyamine-sterol conjugates: the impact of rigid vs. flexible linkers.

Wen-Hua Chen, Bo-Chi Wang, Yong-Ming Lu, 2013, Organic & biomolecular chemistry.

Synthesis and ionophoric activities of functionalized bis(choloyl) conjugates with a rigid core.

Wen-Hua Chen, Jia Zhou, Yong-Ming Lu, 2013, Bioorganic & medicinal chemistry letters.

Discovery of polymethoxyphenyl-pyridines bearing amino side chains as tubulin colchicine-binding site inhibitors.

Xiaoyang Li, Huanxian Wu, Shaoyu Wu, 2022, Bioorganic & medicinal chemistry.

Advances in the development of phosphodiesterase 7 inhibitors.

Jianming Huang, Zhong-Zhen Zhou, Jiang-Ping Xu, 2023, European journal of medicinal chemistry.

Discovery of N-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses.

Hui Yu, Zhong-Zhen Zhou, Hai-Tao Wang, 2017, ACS chemical neuroscience.

Discovery of Novel 3-Amino-4-alkoxyphenylketones as PDE4 Inhibitors with Improved Oral Bioavailability and Safety against Spatial Memory Impairments.

Zhong-Zhen Zhou, JiaPeng He, Jiang-Ping Xu, 2022, ACS chemical neuroscience.

Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings.

Chang Huang, Zhong-Zhen Zhou, Hai-Tao Wang, 2016, European journal of medicinal chemistry.

Microwave-assisted efficient synthesis of 2-hydroxydeoxybenzoins from the alkali degradation of readily prepared 3-aryl-4-hydroxycoumarins in water.

Wen-Hua Chen, Zhong-Zhen Zhou, Xuechun Yang, 2013, Chemical & pharmaceutical bulletin.

Microwave‐Assisted Efficient Synthesis of 2‐Hydroxydeoxybenzoins from the Alkali Degradation of Readily Prepared 3‐Aryl‐4‐hydroxycoumarins in Water.

Wen-Hua Chen, Zhong-Zhen Zhou, Xuechun Yang, 2014 .

Chlorbipram: a novel PDE4 inhibitor with improved safety as a potential antidepressant and cognitive enhancer.

Zhong-Zhen Zhou, Jiang-Ping Xu, Yufang Cheng, 2013, European journal of pharmacology.

Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure-activity relationships.

Zhong-Zhen Zhou, Jiang-Ping Xu, Hai-Tao Wang, 2017, European journal of medicinal chemistry.

N-[2-(6-Methyl-4-oxo-4H-chromen-3-yl)-4-oxothiazolidin-3-yl]furan-2-carboxamide N,N-dimethylformamide solvate

Pei-Liang Zhao, Zhong-Zhen Zhou, Zhong-Zhen Zhou, 2009, Acta crystallographica. Section E, Structure reports online.

An overview of phosphodiesterase 9 inhibitors: Insights from skeletal structure, pharmacophores, and therapeutic potential.

Zhong-Zhen Zhou, Lei Zheng, 2023, European journal of medicinal chemistry.

Synthesis, selective cytotoxicities and probable mechanism of action of 7-methoxy-3-arylflavone-8-acetic acids.

Wen-Hua Chen, Chun-ping Gu, Le Yu, 2014, Bioorganic & medicinal chemistry.