Hilkka Soininen

发表

Fast and robust multi-atlas segmentation of brain magnetic resonance images

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2010, NeuroImage.

Improved generation of probabilistic atlases for the expectation maximization classification

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2011, 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

A prospective validation study of the predictnd tool: A diagnostic decision support tool—rationale and design of the study

Gunhild Waldemar, Marie Bruun, Hilkka Soininen, 2015, Alzheimer's & Dementia.

Extended boundary shift integral

Juha Koikkalainen, Jyrki Lötjönen, Sébastien Ourselin, 2014, 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI).

Multi-template tensor-based morphometry: Application to analysis of Alzheimer's disease

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2011, NeuroImage.

Development and Validation of an Interactive Internet Platform for Older People: The Healthy Ageing Through Internet Counselling in the Elderly Study.

Hilkka Soininen, Miia Kivipelto, Sandrine Andrieu, 2017, Telemedicine journal and e-health : the official journal of the American Telemedicine Association.

Hippocampal atrophy rate using an expectation maximization classifier with a disease-specific prior

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2012, 2012 9th IEEE International Symposium on Biomedical Imaging (ISBI).

Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment

Arthur W. Toga, Zhuowen Tu, Magda Tsolaki, 2011, NeuroImage.

Classification Models for Alzheimer's Disease Detection

Magda Tsolaki, Bruno Vellas, Ioannis Giannoukos, 2013, EANN.

Regional Strength of Large-Scale Functional Brain Networks is Associated with Regional Volumes in Older Adults and in Alzheimer's Disease

Matteo De Marco, Hilkka Soininen, Annalena Venneri, 2021, Brain Connect..

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Eden R Martin, Seth Love, Brian Lawlor, 2019, Nature Genetics.

Structural MRI in Frontotemporal Dementia: Comparisons between Hippocampal Volumetry, Tensor-Based Morphometry and Voxel-Based Morphometry

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2012, PloS one.

Improved Classification of Alzheimer's Disease Data via Removal of Nuisance Variability

Juha Koikkalainen, Jyrki Lötjönen, Harri Pölönen, 2012, PloS one.

Hippocampal plasticity in Alzheimer's disease: changes in highly polysialylated NCAM immunoreactivity in the hippocampal formation

Hilkka Soininen, Irina Alafuzoff, H. Soininen, 1999, The European journal of neuroscience.

Genetic architecture of subcortical brain structures in 38,851 individuals

Benjamin S Aribisala, Tien Yin Wong, Wiro J Niessen, 2019, Nature Genetics.

Distinct and overlapping fMRI activation networks for processing of novel identities and locations of objects

Maija Pihlajamäki, Tuomo Hänninen, Hilkka Soininen, 2005, The European journal of neuroscience.

Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer’s Disease in Two Independent Cohorts

Magda Tsolaki, Bruno Vellas, J-Sebastian Muehlboeck, 2013, Brain Topography.

Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study

Hilkka Soininen, Miia Kivipelto, Jaakko Tuomilehto, 2006, The Lancet Neurology.

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

Hilkka Soininen, Alice Lu, Lars Bertram, 2010, Alzheimer's & Dementia.

Synergistic effect of apolipoprotein E ϵ4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease

Hilkka Soininen, Clive Ballard, Steven H Ferris, 2008, Pharmacogenetics and genomics.

Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging

Andrea Pigorini, Marcello Massimini, Olivia Gosseries, 2011, Neuroreport.

A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein ε4 allele

Arto Mannermaa, Hilkka Soininen, H. Soininen, 1995, Neuroscience Letters.

Discrimination of tetrahydroaminoacridine responders by a single dose pharmaco-EEG in patients with Alzheimer's disease

Juhani Partanen, Hilkka Soininen, H. Soininen, 1991, Neuroscience Letters.

Plasma Based Markers of [11C] PiB-PET Brain Amyloid Burden

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2012, PloS one.

Progression of Alzheimer's disease during a three-year follow-up using the CERAD-NB total score: Kuopio ALSOVA study

Tuomo Hänninen, Hilkka Soininen, Ilona Hallikainen, 2013, International Psychogeriatrics.

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

Lars Bäckman, Tuomo Hänninen, Hilkka Soininen, 2015, The Lancet.

Do Instrumental Activities of Daily Living Predict Dementia at 1‐ and 2‐Year Follow‐Up? Findings from the Development of Screening Guidelines and Diagnostic Criteria for Predementia Alzheimer's Disease Study

Magda Tsolaki, Bruno Vellas, Harald Hampel, 2011, Journal of the American Geriatrics Society.

Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment

Maija Pihlajamäki, Eini Niskanen, Tuomo Hänninen, 2009, Hippocampus.

Application of the PredictAD Software Tool to Predict Progression in Patients with Mild Cognitive Impairment

Jyrki Lötjönen, Gunhild Waldemar, Hilkka Soininen, 2012, Dementia and Geriatric Cognitive Disorders.

Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition

Magda Tsolaki, Lena Cavallin, Bruno Vellas, 2016, European Radiology.

Injury markers predict time to dementia in subjects with MCI and amyloid pathology

Daniel Rueckert, Robin Wolz, Magda Tsolaki, 2012, Neurology.

Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease--cytokines and MRI measures together predict disease progression.

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2011, Journal of Alzheimer's disease : JAD.

J-ADNI and selection of cognition measures

Hilkka Soininen, H. Soininen, T. Iwatsubo, 2010, Alzheimer's & Dementia.

Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study.

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2010, Journal of Alzheimer's disease : JAD.

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Tariq Ahmad, Patrick F. Sullivan, Andres Metspalu, 2020, Nature Communications.

Diagnosis of Alzheimer’s disease: MRI of the hippocampus vs delayed recall

Tuomo Hänninen, Hilkka Soininen, Merja Hallikainen, 2000, Neuropsychologia.

Increased fMRI responses during encoding in mild cognitive impairment

Maija Pihlajamäki, Pasi A. Karjalainen, Eini Niskanen, 2007, Neurobiology of Aging.

Determinants of costs of care for patients with Alzheimer's disease

Gunhild Waldemar, Hilkka Soininen, Linus Jönsson, 2006, International journal of geriatric psychiatry.

Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression.

Hilkka Soininen, Roman A Zubarev, H. Soininen, 2014, Journal of Alzheimer's disease : JAD.

Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease.

Hilkka Soininen, Miia Kivipelto, Laura Fratiglioni, 2005, Archives of neurology.

Novel genetic loci associated with hippocampal volume

Benjamin S Aribisala, Wiro J Niessen, Peter Kochunov, 2017, Nature Communications.

Differential diagnosis of neurodegenerative diseases using structural MRI data

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2016, NeuroImage: Clinical.

Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women

Arto Mannermaa, Tuomo Hänninen, Hilkka Soininen, 2005, European Journal of Human Genetics.

Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation

Jens C. Pruessner, Clifford R. Jack, Marina Boccardi, 2015, Alzheimer's & Dementia.

Prevalence of mild cognitive impairment: A population-based study in elderly subjects

Hilkka Soininen, Matti Vanhanen, Merja Hallikainen, 2000, Neurobiology of Aging.

Predicting AD Conversion: Comparison between Prodromal AD Guidelines and Computer Assisted PredictAD Tool

Juha Koikkalainen, Jyrki Lötjönen, Gunhild Waldemar, 2013, PloS one.

Optimizing the diagnosis of early Alzheimer's disease in mild cognitive impairment subjects.

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2012, Journal of Alzheimer's disease : JAD.

The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

D. Louis Collins, Liana G. Apostolova, Paul M. Thompson, 2015, Alzheimer's & Dementia.

Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease

Yi Zhang, Magda Tsolaki, Bruno Vellas, 2011, PloS one.

Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer’s Disease in Two Independent Cohorts

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2014, Brain Topography.

Diffusion tensor imaging and Tract-Based Spatial Statistics in Alzheimer's disease and mild cognitive impairment

Hilkka Soininen, Mervi Könönen, Miia Kivipelto, 2011, Neurobiology of Aging.

Web-Based Interventions Targeting Cardiovascular Risk Factors in Middle-Aged and Older People: A Systematic Review and Meta-Analysis

Hilkka Soininen, Miia Kivipelto, Carol Brayne, 2016, Journal of medical Internet research.

Remodeling of neuronal circuitries in human temporal lobe epilepsy: Increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex

Asla Pitkänen, Hilkka Soininen, Reetta Kälviäinen, 1998, Annals of neurology.

The Effect of Age Correction on Multivariate Classification in Alzheimer’s Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2015, Brain Topography.

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Benjamin S Aribisala, Wiro J Niessen, Peter Kochunov, 2016, Nature Neuroscience.

Harmonized benchmark labels of the hippocampus on magnetic resonance: The EADC-ADNI project

Liana G. Apostolova, Jens C. Pruessner, Clifford R. Jack, 2015, Alzheimer's & Dementia.

Distribution and Pattern of Pathology in Subjects with Familial or Sporadic Late-Onset Cerebellar Ataxia as Assessed by p62/Sequestosome Immunohistochemistry

Hilkka Soininen, Maria Pikkarainen, Irina Alafuzoff, 2011, The Cerebellum.

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease

Ariadna Besga, Hilkka Soininen, Miia Kivipelto, 2009, Neuroscience Letters.

Visual assessment of medial temporal atrophy on MR films in Alzheimer’s disease: comparison with volumetry

Cristina Geroldi, Alberto Beltramello, Hilkka Soininen, 2005, Aging clinical and experimental research.

Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

Giovanni B. Frisoni, Alfredo Robles, Takeshi Iwatsubo, 1998 .

Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study.

Minna Rusanen, Hilkka Soininen, Miia Kivipelto, 2014, Journal of Alzheimer's disease : JAD.

Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2013, Journal of Alzheimer's disease : JAD.

Longitudinal changes of CSF biomarkers in Alzheimer's disease.

Hilkka Soininen, H. Soininen, P. Hartikainen, 2011, Journal of Alzheimer's disease : JAD.

Five-class differential diagnostics of neurodegenerative diseases using random undersampling boosting

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2017, NeuroImage: Clinical.

Slowing of the dominant occipital rhythm in electroencephalogram is associated with low concentration of noradrenaline in the thalamus in patients with Alzheimer's disease

Esa Mervaala, Hilkka Soininen, Eeva-Liisa Helkala, 1992, Neuroscience Letters.

Discovery and use of efficient biomarkers for objective disease state assessment in Alzheimer's disease

Juha Koikkalainen, Hilkka Soininen, Mark van Gils, 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

CSF Abeta42, tau and phosphorylated tau correlate with medial temporal lobe atrophy.

Hilkka Soininen, Corina Pennanen, H. Soininen, 2008, Journal of Alzheimer's disease : JAD.

Survey of segmentation protocols for manual hippocampal volumetry: Preparatory phase for an EADC-ADNI harmonization protocol

Clifford R. Jack, Marina Boccardi, Giovanni B. Frisoni, 2010, Alzheimer's & Dementia.

The AddNeuroMed framework for multi‐centre MRI assessment of Alzheimer's disease : experience from the first 24 months

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2011, International journal of geriatric psychiatry.

Relationship between hippocampal atrophy and neuropathology markers: A 7T MRI validation study of the EADC-ADNI Harmonized Hippocampal Segmentation Protocol

Liana G. Apostolova, Jens C. Pruessner, Clifford R. Jack, 2015, Alzheimer's & Dementia.

Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance

Liana G. Apostolova, Jens C. Pruessner, Clifford R. Jack, 2015, Alzheimer's & Dementia.

Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

Magda Tsolaki, Bruno Vellas, Hilkka Soininen, 2014, PLoS medicine.

Encoding of novel picture pairs activates the perirhinal cortex: An fMRI study

Maija Pihlajamäki, Tuomo Hänninen, Hilkka Soininen, 2003, Hippocampus.

Estimating the impact of differences among protocols for manual hippocampal segmentation on Alzheimer's disease-related atrophy: Preparatory phase for a harmonized protocol

Marina Boccardi, Martina Bocchetta, Rossana Ganzola, 2011, Alzheimer's & Dementia.

Frontotemporal dementia as a neural system disease

Marina Boccardi, Giovanni B. Frisoni, Alberto Beltramello, 2005, Neurobiology of Aging.

Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment

Giovanni B. Frisoni, Gunhild Waldemar, Juha O. Rinne, 2017, Alzheimer's & Dementia.

Gait as predictor of dementia

Jyrki Lötjönen, Juha Pärkkä, Mark van Gils, 2017 .

A comparison between the accuracy of voxel‐based morphometry and hippocampal volumetry in Alzheimer's disease

Alberto Beltramello, Hilkka Soininen, Francesca Sabattoli, 2004, Journal of magnetic resonance imaging : JMRI.

Patient- and Proxy-Reported Utility in Alzheimer Disease Using the EuroQoL

Gunhild Waldemar, Hilkka Soininen, Linus Jönsson, 2006, Alzheimer disease and associated disorders.

EEG AND COMPUTED TOMOGRAPHY IN THE INVESTIGATION OF PATIENTS WITH SENILE DEMENTIA:

Hilkka Soininen, J. Partanen, M. Puranen, 1982 .

Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2014, Alzheimer's & Dementia.

Combination of Biomarkers: PET [18F]Flutemetamol Imaging and Structural MRI in Dementia and Mild Cognitive Impairment

Juha Koikkalainen, Jyrki Lötjönen, David J. Brooks, 2012, Neurodegenerative Diseases.

Automatic temporal lobe atrophy assessment in prodromal AD: Data from the DESCRIPA study

Roberto Bellotti, Philip Scheltens, Hilkka Soininen, 2014, Alzheimer's & Dementia.

Relationship between apoE genotype and CSF β-amyloid (1–42) and tau in patients with probable and definite Alzheimer’s disease

Hilkka Soininen, Irina Alafuzoff, H. Soininen, 2000, Neurobiology of Aging.

Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers

Hilkka Soininen, Kaj Blennow, Michael Flory, 2005, Annals of neurology.

Cortical thickness in frontotemporal dementia, mild cognitive impairment, and Alzheimer's disease.

Eini Niskanen, Hilkka Soininen, Miia Kivipelto, 2012, Journal of Alzheimer's disease : JAD.

Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans

Maija Pihlajamäki, Tuomo Hänninen, Hilkka Soininen, 2004, The European journal of neuroscience.

Delphi Consensus on Landmarks for the Manual Segmentation of the Hippocampus on MRI: Preliminary Results from the EADC-ADNI Harmonized Protocol Working Group (S04.003)

Liana G. Apostolova, Jens C. Pruessner, Charles DeCarli, 2012 .

CSF Abeta42, Tau and phosphorylated Tau, APOE epsilon4 allele and MCI type in progressive MCI.

Hilkka Soininen, Susanna Tervo, Merja Hallikainen, 2007, Neurobiology of aging.

Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment

Hilkka Soininen, Miia Kivipelto, Carol Brayne, 2016, Alzheimer's & Dementia.

Plasma proteins predict conversion to dementia from prodromal disease

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2014, Alzheimer's & Dementia.

Hippocampus in Alzheimer’s disease: a 3-year follow-up MRI study

Hilkka Soininen, H. Soininen, M. Laakso, 2000, Biological Psychiatry.

Heterogeneous patterns of brain atrophy in Alzheimer's disease

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2018, Neurobiology of Aging.

MANAGEMENT OF VASCULAR AND LIFESTYLE-RELATED RISK FACTORS FOR ALZHEIMER'S DISEASE AND DEMENTIA IN OLDER ADULTS: A EUROPEAN PERSPECTIVE

Hilkka Soininen, Miia Kivipelto, Carol Brayne, 2014, Alzheimer's & Dementia.

The MRI pattern of frontal and temporal brain atrophy in fronto-temporal dementia

Marina Boccardi, Cristina Geroldi, Alberto Beltramello, 2003, Neurobiology of Aging.

Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2012, Journal of Translational Medicine.

Structural and functional MRI in mild cognitive impairment.

Maija Pihlajamäki, Hilkka Soininen, H. Soininen, 2009, Current Alzheimer research.

CSF Aβ42, Tau and phosphorylated Tau, APOE ɛ4 allele and MCI type in progressive MCI

Hilkka Soininen, Susanna Tervo, Merja Hallikainen, 2007, Neurobiology of Aging.

Whole brain atrophy rate predicts progression from MCI to Alzheimer’s disease

Eini Niskanen, Hilkka Soininen, Eric M. Reiman, 2010, Neurobiology of Aging.

Protective variant for hippocampal atrophy identified by whole exome sequencing

Li Shen, Magda Tsolaki, Clifford R Jack, 2015, Annals of neurology.

Software Tool for Improved Prediction of Alzheimer’s Disease

Juha Koikkalainen, Jyrki Lötjönen, Daniel Rueckert, 2011, Neurodegenerative Diseases.

The Alzheimer’s Association external quality control program for cerebrospinal fluid biomarkers

Giovanni B. Frisoni, José Luis Molinuevo, Aase Handberg, 2011, Alzheimer's & Dementia.

Definition of harmonized protocol for hippocampal segmentation

Charles DeCarli, Marina Boccardi, Martina Bocchetta, 2012, Alzheimer's & Dementia.

Circulating Proteomic Signatures of Chronological Age

Magda Tsolaki, Bruno Vellas, Hilkka Soininen, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Quantitative evaluation of disease progression in a longitudinal mild cognitive impairment cohort.

Juha Koikkalainen, Jyrki Lötjönen, Hilkka Soininen, 2014, Journal of Alzheimer's disease : JAD.

Apolipoprotein E 4 Allele, Elevated Midlife Total Cholesterol Level, and High Midlife Systolic Blood Pressure Are Independent Risk Factors for Late-Life Alzheimer Disease

Arto Mannermaa, Hilkka Soininen, Miia Kivipelto, 2002, Annals of Internal Medicine.

Structure and function of medial temporal and posteromedial cortices in early Alzheimer’s disease

Maija Pihlajamäki, Eini Niskanen, Tuomo Hänninen, 2011, The European journal of neuroscience.

Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B.

Sakari Savolainen, Kjell Någren, Ville Leinonen, 2008, Archives of neurology.

How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer’s disease? A review of neuroimaging studies

Hilkka Soininen, Giovanni B Frisoni, G. Frisoni, 2000, Neurobiology of Aging.

Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations

Hilkka Soininen, Sandro Sorbi, Philippe Amouyel, 2011, Neurobiology of Aging.

The Effect of Apolipoprotein Polymorphism on Brain in Mild Cognitive Impairment: A Voxel-Based Morphometric Study

Marina Boccardi, Tuomo Hänninen, Hilkka Soininen, 2006, Dementia and Geriatric Cognitive Disorders.

Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials

Michèle Allard, Olivier Rouaud, Carole Dufouil, 2019, Alzheimer's & Dementia.

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.

Susan M Resnick, Magda Tsolaki, Luigi Ferrucci, 2010, Archives of general psychiatry.

Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

Magda Tsolaki, Richard Dobson, Bruno Vellas, 2012, Human molecular genetics.

CSF Aβ42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment

Hilkka Soininen, Merja Hallikainen, H. Soininen, 2005, Neurology.

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

Juha Koikkalainen, Jyrki Lötjönen, Riitta Parkkola, 2019, Alzheimer's Research & Therapy.

Common brain disorders are associated with heritable patterns of apparent aging of the brain

Anders M. Dale, Lars T. Westlye, Mona K. Beyer, 2019, Nature Neuroscience.

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models

Juha E. Jääskeläinen, Ville Leinonen, Hilkka Soininen, 2015, Neurobiology of Aging.

ABNORMAL NETWORK ORGANIZATION IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE

Magda Tsolaki, Bruno Vellas, Giovanni Volpe, 2016, Alzheimer's & Dementia.

New Insights into Alzheimer's Disease Progression: A Combined TMS and Structural MRI Study

Marcello Massimini, Esa Mervaala, Eini Niskanen, 2011, PloS one.

THA disrupts mismatch negativity in Alzheimer disease

Juhani Partanen, Hilkka Soininen, Jari Karhu, 1997, Psychopharmacology.

A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease.

Aki Vehtari, Kimmo Kaski, Olli Gröhn, 2008, Biochemical and biophysical research communications.

A Longitudinal Quantitative EEG Study of Alzheimer’s Disease: Relation to Apolipoprotein E Polymorphism

Juhani Partanen, Hilkka Soininen, Mervi Könönen, 2000, Dementia and Geriatric Cognitive Disorders.

Evolution of global and local grey matter atrophy on serial MRI scans during the progression from MCI to AD.

Eini Niskanen, Hilkka Soininen, Miia Kivipelto, 2012, Current Alzheimer research.

The Use of MRI and PET for Clinical Diagnosis of Dementia and Investigation of Cognitive Impairment : A Consensus Report

William J. Jagust, Ronald C. Petersen, Norman L. Foster, 2004 .

Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study

Magda Tsolaki, Harald Hampel, Philip Scheltens, 2009, The Lancet Neurology.

Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2014, Front. Aging Neurosci..

Radial width of the temporal horn: a sensitive measure in Alzheimer disease.

Charles DeCarli, Cristina Geroldi, Alberto Beltramello, 2002, AJNR. American journal of neuroradiology.

Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer’s disease

Arto Mannermaa, Tuomo Hänninen, Hilkka Soininen, 2005, Journal of Neurology.

Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.

John Seibyl, Vladimir Coric, Hilkka Soininen, 2015, JAMA neurology.

APOE ε2 Allele Is Associated with Larger Regional Cortical Thicknesses and Volumes

Alan C. Evans, Magda Tsolaki, Bruno Vellas, 2010, Dementia and Geriatric Cognitive Disorders.

Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

Daniel Rueckert, Robin Wolz, Martina Bocchetta, 2013, Neurobiology of Aging.

Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

Minna Rusanen, Hilkka Soininen, Miia Kivipelto, 2015, Alzheimer's & Dementia.

Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus

Jyrki Lötjönen, Anna Sutela, Ville Leinonen, 2016, Acta Neurochirurgica.

Candidate blood proteome markers of Alzheimer's disease onset and progression: A systematic review and replication study

Magda Tsolaki, Bruno Vellas, Eric Westman, 2013, Alzheimer's & Dementia.

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Michael W. Weiner, Anders M. Dale, Robert C. Green, 2017, bioRxiv.

Alzheimer's Disease‐Associated Ubiquilin‐1 Regulates Presenilin‐1 Accumulation and Aggresome Formation

Hilkka Soininen, Alice Lu, Lars Bertram, 2011, Traffic.

Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers

Magda Tsolaki, Harald Hampel, Philip Scheltens, 2017, Alzheimer's & Dementia.

A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer’s Disease Diagnosis

Magda Tsolaki, Bruno Vellas, Hilkka Soininen, 2015, Journal of Alzheimer's disease : JAD.

Spectral analysis of EEG in Alzheimer's disease: Relation to apolipoprotein E polymorphism

Juhani Partanen, Arto Mannermaa, Hilkka Soininen, 1996, Neurobiology of Aging.

A blood gene expression marker of early Alzheimer's disease.

Magda Tsolaki, Richard Dobson, Bruno Vellas, 2013, Journal of Alzheimer's disease : JAD.

The interactive effect of demographic and clinical factors on hippocampal volume: A multicohort study on 1958 cognitively normal individuals

Magda Tsolaki, Bruno Vellas, Andrew Simmons, 2017, Hippocampus.

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Tariq Ahmad, Patrick F. Sullivan, Andres Metspalu, 2019, bioRxiv.

Psychopathy and the posterior hippocampus

Hannu J. Aronen, Hilkka Soininen, Jari Tiihonen, 2001, Behavioural Brain Research.

Combining Transcranial Magnetic Stimulation and Electroencephalography May Contribute to Assess the Severity of Alzheimer's Disease

Petro Julkunen, Hilkka Soininen, Ari Pääkkönen, 2011, International journal of Alzheimer's disease.

Prevalence of mild cognitive impairment: a population‐based study in elderly subjects

Tuomo Hänninen, Hilkka Soininen, Matti Vanhanen, 2002, Acta neurologica Scandinavica.

Predicting progression from cognitive impairment to Alzheimer's disease with the Disease State Index.

Juha Koikkalainen, Robin Wolz, Harald Hampel, 2015, Current Alzheimer research.