Mathieu Vinken

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Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action.

Thomas Hartung, Imran Shah, Jennifer Seed, 2014, ALTEX.

The adverse outcome pathway concept: a pragmatic tool in toxicology.

Mathieu Vinken, M. Vinken, 2013, Toxicology.

A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.

Bertrand Desprez, Martina Klaric, Gladys Ouédraogo, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2012, Critical reviews in toxicology.

What is understood by "animal-free research"?

Sandra Coecke, Mathieu Vinken, Jan van der Valk, 2019, Toxicology in vitro : an international journal published in association with BIBRA.

New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment.

Bas J Blaauboer, Alicia Paini, Paul Jennings, 2020, ALTEX.

New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop.

Catherine Mahony, Sebastian Maurer-Stroh, Thomas B Knudsen, 2020, Regulatory toxicology and pharmacology : RTP.

3Rs toxicity testing and disease modeling projects in the European Horizon 2020 research and innovation program

Mathieu Vinken, M. Vinken, 2020, EXCLI journal.

Omics-based input and output in the development and use of adverse outcome pathways

Mathieu Vinken, M. Vinken, 2019, Current Opinion in Toxicology.

Adverse outcome pathways: a concise introduction for toxicologists

Jan G. Hengstler, Dries Knapen, Maurice Whelan, 2017, Archives of Toxicology.

Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction

Jan Vanfleteren, Mathieu Vinken, Magnus Jaeger, 2016, Proceedings of the National Academy of Sciences.

Adverse Outcome Pathways as Tools to Assess Drug-Induced Toxicity.

Mathieu Vinken, M. Vinken, 2016, Methods in molecular biology.

Connexins and their channels in cell growth and cell death.

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2006, Cellular signalling.

Taking adverse outcome pathways to the next level.

Mathieu Vinken, M. Vinken, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Adverse Outcome Pathways and Drug-Induced Liver Injury Testing.

Mathieu Vinken, M. Vinken, 2015, Chemical research in toxicology.

Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2006, Current drug metabolism.

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

Valérie Zuang, George Loizou, Andrew Worth, 2011, Archives of Toxicology.

In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death.

Bas J Blaauboer, Mathieu Vinken, M. Vinken, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

Adverse outcome pathway development from protein alkylation to liver fibrosis

Sharon Munn, Brigitte Landesmann, Tomislav Horvat, 2016, Archives of Toxicology.

Adverse outcome pathways: hype or hope?

Vera Rogiers, Maurice Whelan, Mathieu Vinken, 2013, Archives of Toxicology.

Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells.

Vera Rogiers, Maxime Culot, Mathieu Vinken, 2009, Cell calcium.

Introduction: connexins, pannexins and their channels as gatekeepers of organ physiology

Mathieu Vinken, M. Vinken, 2015, Cellular and Molecular Life Sciences.

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays.

Raffaella Corvi, Susanna-Assunta Sansone, Philippe Rocca-Serra, 2008, Mutation research.

Strategies for immortalization of primary hepatocytes.

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2014, Journal of hepatology.

Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.

Imran Shah, Brigitte Landesmann, Vera Rogiers, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Modelling Long-Term Repeat-Dose Toxicity – Challenges Faced

Vera Rogiers, Mathieu Vinken, V. Rogiers, 2006 .

Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation and stem cell reprogrammation.

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2009, Journal of hepatology.

Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance?

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

The dual face of connexin-based astroglial Ca(2+) communication: a key player in brain physiology and a prime target in pathology.

Nan Wang, Mathieu Vinken, Luc Leybaert, 2014, Biochimica et biophysica acta.

Involvement of Cell Junctions in Hepatocyte Culture Functionality

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2006, Critical reviews in toxicology.

MicroRNAs as key regulators of xenobiotic biotransformation and drug response

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2014, Archives of Toxicology.

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

Paul Jennings, Alice Limonciel, Bob van de Water, 2018, Archives of Toxicology.

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report.

Marianna Gaça, Miyoung Yoon, Marco Corvaro, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Towards an integrated in vitro strategy for repeated dose toxicity testing

Vera Rogiers, Mathieu Vinken, Tamara Vanhaecke, 2011, Archives of Toxicology.