M. Howard

发表

A novel DMD IRES results in a functional N-truncated dystrophin, providing a potential route to therapy for patients with 5’ mutations

M. Uhlén, R. Weiss, D. Dunn, 2014, Nature medicine.

Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice

M. Uhlén, C. Szigyarto, R. Weiss, 2014, Nature Medicine.

A tRNA modifying enzyme as a tunable regulatory nexus for bacterial stress responses and virulence

Adam J. Lewis, L. Baird, M. Hadjifrangiskou, 2022, Nucleic acids research.

Acute Effects of Cheddar Cheese Consumption on Circulating Amino Acids and Human Skeletal Muscle

M. Drummond, P. Reidy, L. Baird, 2021, Nutrients.

Nonsense mutation‐associated Becker muscular dystrophy: interplay between exon definition and splicing regulatory elements within the DMD gene

R. Finkel, B. Wong, A. Pestronk, 2011, Human mutation.

Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.

M. Drummond, P. Reidy, Ziad S. Mahmassani, 2019, Journal of applied physiology.

DMD Trp3X nonsense mutation associated with a founder effect in North American families with mild Becker muscular dystrophy

Carol J. Saunders, G. Comi, R. Finkel, 2009, Neuromuscular Disorders.

Becker muscular dystrophy with widespread muscle hypertrophy and a non-sense mutation of exon 2

R. Weiss, K. Flanigan, O. Gurvich, 2013, Neuromuscular Disorders.

Cryptic MHC class I-binding peptides are revealed by aminoglycoside-induced stop codon read-through into the 3′ UTR

K. Flanigan, J. F. Atkins, L. Eisenlohr, 2014, Proceedings of the National Academy of Sciences.

The Blue Obelisk—Interoperability in Chemical Informatics

Egon L. Willighagen, Rajarshi Guha, Christoph Steinbeck, 2006, J. Chem. Inf. Model..

Drosophila topoisomerase II-DNA interactions are affected by DNA structure.

J. Griffith, T. Hsieh, M. Howard, 1991, Journal of molecular biology.

Selenoprotein Gene Nomenclature*

R. Guigó, S. Castellano, G. Kryukov, 2016, The Journal of Biological Chemistry.

Antisense-induced ribosomal frameshifting

C. Anderson, C. Henderson, M. Howard, 2006, Nucleic acids research.

Programmed ribosomal frameshifting in decoding the SARS-CoV genome

Pavel V Baranov, C. Anderson, J. F. Atkins, 2005, Virology.

Readthrough of dystrophin stop codon mutations induced by aminoglycosides

Uwe Fass, Kevin M Flanigan, C. Anderson, 2004, Annals of neurology.

Sequence specificity of aminoglycoside‐induced stop codon readthrough: Potential implications for treatment of Duchenne muscular dystrophy

K. Flanigan, R. Gesteland, B. Shirts, 2000, Annals of neurology.

Polyamine analogs with xylene rings induce antizyme frameshifting, reduce ODC activity, and deplete cellular polyamines.

J. F. Atkins, R. Gesteland, D. Kramer, 2006, Journal of biochemistry.

Independent evolution of bitter-taste sensitivity in humans and chimpanzees

M. Bamshad, D. Dunn, S. Wooding, 2006, Nature.

Clinical and genetic characterization of manifesting carriers of DMD mutations

R. Finkel, B. Wong, A. Pestronk, 2010, Neuromuscular Disorders.

Divergent regulation of the key enzymes of polyamine metabolism by chiral -methylated polyamine analogs

C. Anderson, L. Alhonen, J. Vepsäläinen, 2020 .

Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues.

C. Anderson, L. Alhonen, J. Vepsäläinen, 2009, The Biochemical journal.

Polyamine sensing during antizyme mRNA programmed frameshifting.

J. F. Atkins, R. Gesteland, M. Howard, 2005, Biochemical and biophysical research communications.

Cell culture analysis of the regulatory frameshift event required for the expression of mammalian antizymes

S. Matsufuji, R. Gesteland, B. Shirts, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Overriding standard decoding: implications of recoding for ribosome function and enrichment of gene expression.

J. F. Atkins, S. Matsufuji, R. Gesteland, 2001, Cold Spring Harbor symposia on quantitative biology.

Molecular mechanism of eukaryotic selenocysteine incorporation

P. Copeland, M. Howard, Jonathan N. Gonzales-Flores, 2011 .

Epitopes Derived by Incidental Translational Frameshifting Give Rise to a Protective CTL Response1

J. F. Atkins, L. Eisenlohr, G. Sinnathamby, 2006, The Journal of Immunology.

This information is current as Response Frameshifting Give Rise to a Protective CTL Epitopes Derived by Incidental Translational

J. F. Atkins, L. Eisenlohr, G. Sinnathamby, 2006 .

Recoding elements located adjacent to a subset of eukaryal selenocysteine‐specifying UGA codons

M. T. Howard, G. Aggarwal, C. Anderson, 2005, The EMBO journal.

Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides.

J. F. Atkins, R. Gesteland, M. Howard, 2004, RNA.

Erratum: Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice: (Nature Medicine (2014) 20 (992-1000) DOI:10.1038/nm.3628)

M. Uhlén, C. Szigyarto, R. Weiss, 2015 .

The ZZ Domain of Dystrophin in DMD: Making Sense of Missense Mutations

K. Flanigan, J. Ervasti, A. Vulin, 2014, Human mutation.

DMD exon 1 truncating point mutations: Amelioration of phenotype by alternative translation initiation in exon 6

R. Weiss, G. Aggarwal, K. Flanigan, 2009, Human mutation.

Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort

Livija Medne, Amy Meyer, R. Finkel, 2009, Human mutation.

Disuse-induced insulin resistance susceptibility coincides with a dysregulated skeletal muscle metabolic transcriptome.

M. Drummond, P. Reidy, Ziad S. Mahmassani, 2019, Journal of applied physiology.

Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle

T. Crawford, M. T. Howard, K. Flanigan, 2008, Proceedings of the National Academy of Sciences.

LTBP4 genotype predicts age of ambulatory loss in duchenne muscular dystrophy

Craig McDonald, Kevin M Flanigan, Jerry R Mendell, 2013, Annals of neurology.

Conserved regions of the DMD 3′ UTR regulate translation and mRNA abundance in cultured myotubes

C. A. Larsen, M. Howard, 2014, Neuromuscular Disorders.

A mutation in the SEPN1 selenocysteine redefinition element (SRE) reduces selenocysteine incorporation and leads to SEPN1‐related myopathy

Mark W. Moyle, C. Anderson, K. Flanigan, 2009, Human mutation.

New Directions for Understanding the Codon Redefinition Required for Selenocysteine Incorporation

P. Copeland, M. Howard, 2019, Biological Trace Element Research.

Reduced Physical Activity Alters the Leucine-Stimulated Translatome in Aged Skeletal Muscle.

M. Drummond, L. Baird, Ziad S. Mahmassani, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

DMD pseudoexon mutations: splicing efficiency, phenotype, and potential therapy

R. Finkel, R. Weiss, C. Anderson, 2008, Annals of neurology.

Leucine Differentially Regulates Gene-Specific Translation in Mouse Skeletal Muscle.

M. T. Howard, B. Dalley, M. Drummond, 2017, The Journal of nutrition.

Human selenoprotein P and S variant mRNAs with different numbers of SECIS elements and inferences from mutant mice of the roles of multiple SECIS elements

R. Guigó, M. Capecchi, M. Mariotti, 2016, Open Biology.

Probing Selenoprotein Translation by Ribosome Profiling

M. Howard, 2016 .

The traY Gene Product and Integration Host Factor Stimulate Escherichia coli DNA Helicase I-catalyzed Nicking at the F Plasmid oriT(*)

W. Nelson, S. W. Matson, M. Howard, 1995, The Journal of Biological Chemistry.

Dietary Selenium Levels Affect Selenoprotein Expression and Support the Interferon-γ and IL-6 Immune Response Pathways in Mice

C. Anderson, B. Carlson, D. Hatfield, 2015, Nutrients.

Selenoprotein N: Its Role in Disease

D. Grunwald, A. Lescure, P. Castets, 2011 .

Translational Redefinition of UGA Codons Is Regulated by Selenium Availability*

M. T. Howard, C. Anderson, B. Carlson, 2013, The Journal of Biological Chemistry.

HMf, a histone-related protein from the hyperthermophilic archaeon Methanothermus fervidus, binds preferentially to DNA containing phased tracts of adenines

J. Griffith, J. Reeve, K. Sandman, 1992, Journal of bacteriology.

Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase.

S. W. Matson, K. Kreuzer, M. Howard, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Attenuation of an amino-terminal premature stop codon mutation in the ATRX gene by an alternative mode of translational initiation

C. Anderson, J. F. Atkins, R. Gibbons, 2004, Journal of Medical Genetics.

Reprogramming the Ribosome for Selenoprotein Expression: RNA Elements and Protein Factors

M. T. Howard, M. Berry, M. Howard, 2010 .

A cluster of strong topoisomerase II cleavage sites is located near an integrated human immunodeficiency virus.

J. Griffith, M. Howard, 1993, Journal of molecular biology.

Studying Selenoprotein mRNA Translation Using RNA-Seq and Ribosome Profiling.

B. Dalley, L. Baird, M. Howard, 2018, Methods in molecular biology.

Ribosome Fate during Decoding of UGA-Sec Codons

P. Copeland, M. Howard, 2021, International journal of molecular sciences.

Processive selenocysteine incorporation during synthesis of eukaryotic selenoproteins.

S. M. Fixsen, M. Howard, 2010, Journal of molecular biology.

Stepwise Assembly of a Relaxosome at the F Plasmid Origin of Transfer (*)

W. Nelson, S. W. Matson, M. Howard, 1995, The Journal of Biological Chemistry.

Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations

C. Birchmeier, U. Schweizer, Wenchao Zhao, 2019, The Journal of Biological Chemistry.

Title Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein

M. Mariotti, J. F. Atkins, G. Loughran, 2019 .

Multiple RNA structures affect translation initiation and UGA redefinition efficiency during synthesis of selenoprotein P

M. Mariotti, J. F. Atkins, G. Loughran, 2017, Nucleic acids research.

The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay

C. Anderson, B. Carlson, D. Hatfield, 2016, Nucleic acids research.

Clinical phenotypes as predictors of the outcome of skipping around DMD exon 45

R. Finkel, A. Pestronk, J. Mendell, 2015, Annals of neurology.

A recoding element that stimulates decoding of UGA codons by Sec tRNA[Ser]Sec.

Mark W. Moyle, G. Aggarwal, C. Anderson, 2007, RNA.

Balanced Input from the tRNA Prenyltransferase MiaA Controls the Stress Resistance and Virulence Potential of Extraintestinal Pathogenic Escherichia coli

Adam J. Lewis, L. Baird, V. Bandarian, 2021, bioRxiv.

Avoidance of reporter assay distortions from fused dual reporters

M. T. Howard, J. F. Atkins, A. Firth, 2017, RNA.

A mutation in the SEPN1 SRE reduces selenocysteine incorporation and leads to SEPN1 -related myopathy

Christine, Anderson, Mark W. Moyle, 2011 .