H. Nottet

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Induction of HIV-1 IIIb neutralizing antibodies in BALB/c mice by a chimaeric peptide consisting of a T-helper cell epitope of Semliki Forest virus and a B-cell epitope of HIV.

R. Meloen, B. Golding, H. Golding, 1998, Vaccine.

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.

G. Nuovo, M. Bukrinsky, H. Gendelman, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Role for oxygen radicals in self‐sustained HIV‐1 replication in monocyte‐derived macrophages: enhanced HIV‐1 replication by N‐acetyl‐L‐cysteine

M. Visser, J. Verhoef, B. Asbeck, 1994, Journal of leukocyte biology.

Interactions between major histocompatibility complex class II surface expression and HIV: implications for pathogenesis

E. Breij, H. Nottet, W. Kamp, 2001, European journal of clinical investigation.

Animal Model Human Immunodeficiency Virus Encephalitis in SCID Mice

Ellen, H. Gendelman, L. Epstein, 2007 .

Intracellular pathways involved in TNF-α and superoxide anion release by Aβ(1–42)-stimulated primary human macrophages

J. Verhoef, H. A. Smits, H. Nottet, 2001, Journal of Neuroimmunology.

In-vitro selection of HIV-1 variants resistant to non-nucleoside reverse transcriptase inhibitors in monocyte-derived macrophages.

C. Boucher, J. Verhoef, R. Schuurman, 1997, The Journal of antimicrobial chemotherapy.

Monocyte infiltration is highly associated with loss of the tight junction protein zonula occludens in HIV‐1‐associated dementia

J. Verhoef, C. D. DE GROOT, L. Boven, 2000, Neuropathology and applied neurobiology.

Phagocytic function of monocyte-derived macrophages is not affected by human immunodeficiency virus type 1 infection.

M. Visser, J. Verhoef, J. V. van Strijp, 1993, The Journal of infectious diseases.

Induction of cyclooxygenase‐2 expression during HIV‐1‐infected monocyte‐derived macrophage and human brain microvascular endothelial cell interactions

J. Verhoef, C. Pereira, L. Boven, 2000, Journal of leukocyte biology.

Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS).

M. Huigen, R. D. de Groot, R. Stranska, 2005, International journal of antimicrobial agents.

Mechanism of inhibition of the human immunodeficiency virus type 1 by the oxygen radical generating agent bleomycin.

P. de Bie, C. Jansen, B. S. van Asbeck, 2004, Antiviral research.

Activation of Human Macrophages by Amyloid-β Is Attenuated by Astrocytes1

J. Verhoef, F. L. van Muiswinkel, A. V. van Beelen, 2001, The Journal of Immunology.

Activation of human macrophages by amyloid-beta is attenuated by astrocytes.

F. L. Muiswinkel, J. Verhoef, F. L. van Muiswinkel, 2001, Journal of immunology.

Macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions.

C. D. DE GROOT, L. Boven, H. Nottet, 2000, Clinical and experimental immunology.

The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes.

H. Gendelman, H. Gelbard, J. Reinhard, 1996, Journal of neurovirology.

Interactions between HIV-infected monocyte-derived endothelial cells result in increased expression of CC chemokines

J. Verhoef, D. Schotte, E. Breij, 2000 .

Infection of epithelial cell line HEp‐2 with human immunodeficiency virus type 1 is CD4 dependent

M. Visser, J. Verhoef, I. Janse, 1993, Journal of medical virology.

DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells

Douglas S Kwon, C. Figdor, Y. Kooyk, 2000, Cell.

Increased peroxynitrite activity in AIDS dementia complex: implications for the neuropathogenesis of HIV-1 infection.

P. Portegies, J. Verhoef, M. Tardieu, 1999, Journal of immunology.

Overexpression of nerve growth factor and basic fibroblast growth factor in AIDS dementia complex

G. Jansen, P. Portegies, J. Verhoef, 1999, Journal of Neuroimmunology.

Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.

H. Gendelman, V. Sasseville, S. Swindells, 1996, Journal of immunology.

Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex.

H. Gendelman, H. Gendelman, H. Nottet, 1995, Immunology today.

Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication.

B. Berkhout, L. Marnett, M. Huigen, 2003, Antiviral research.

Macrophage inflammatory protein‐1α (MIP‐1α), MIP‐1β, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions

C. D. DE GROOT, C. J. A. De Groot, L. A. Boven, 2000 .

Amyloid-β-induced chemokine production in primary human macrophages and astrocytes

J. Verhoef, L. Boven, H. A. Smits, 2002, Journal of Neuroimmunology.

Secretases as targets for drug design in Alzheimer’s disease

H. A. Smits, H. Nottet, J. Hendriksen, 2002, European journal of clinical investigation.

Interactions between macrophages and brain microvascular endothelial cells: role in pathogenesis of HIV-1 infection and blood - brain barrier function.

H. Nottet, 1999, Journal of neurovirology.

The development of animal model systems for HIV-1 encephalitis and its associated dementia.

V. Sasseville, L. Epstein, Y. Persidsky, 1995, Journal of neurovirology.

Multiple effects of HIV‐1 trans‐activator protein on the pathogenesis of HIV‐1 infection

M. Huigen, H. Nottet, W. Kamp, 2004, European journal of clinical investigation.

Human immunodeficiency virus encephalitis in SCID mice.

H. Gendelman, L. Epstein, H. Gelbard, 1996, The American journal of pathology.

The neuropathogenesis of HIV‐1 infection

S. Lipton, M. Bukrinsky, H. Gendelman, 1994, Handbook of clinical neurology.

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV- associated neurological disease

S. Lipton, M. Bukrinsky, H. Gendelman, 1995, The Journal of experimental medicine.

Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin

S. Swindells, M. Jett, K. Dzenko, 1994, Journal of virology.

Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection.

C. Boucher, M. Visser, J. Verhoef, 1998, The Journal of infectious diseases.

Interactions of human immunodeficiency virus‐1 proteins with neurons: possible role in the development of human immunodeficiency virus‐1‐associated dementia

C. Pereira, H. Nottet, M. van de Bovenkamp, 2002, European Journal of Clinical Investigation.

Cytokine-Stimulated, But Not HIV-Infected, Human Monocyte-Derived Macrophages Produce Neurotoxic Levels of l-Cysteine1

M. Kaul, S. Lipton, H. Gendelman, 2000, The Journal of Immunology.

Brain-derived human immunodeficiency virus-1 Tat exerts differential effects on LTR transactivation and neuroimmune activation

J. McArthur, C. Power, C. Pardo, 2007, Journal of NeuroVirology.

Role of the pro‐inflammatory cytokines TNF‐α and IL‐1β in HIV‐associated dementia

N. Brabers, H. Nottet, 2006, European journal of clinical investigation.

Interactions between HIV-infected monocyte-derived macrophages and human brain microvascular endothelial cells result in increased expression of CC chemokines.

J. Verhoef, D. Schotte, J. Verhoef, 2000, Journal of neurovirology.

The amino-terminus of the amyloid-β protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages

P. Eikelenboom, F. L. Muiswinkel, J. Verhoef, 1999, Journal of Neuroimmunology.

The neuropathogenesis of HIV-1 infection.

S. Lipton, M. Bukrinsky, H. Gendelman, 1999, Journal of leukocyte biology.

Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants

Pascal Clayette, M. Turco, D. Salvemini, 2001, Trends in Neurosciences.

A regulatory role for astrocytes in HIV-1 encephalitis. An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-1-infected monocytes is attenuated by primary human astrocytes.

A. Rizzino, M. Jett, E. Bernton, 1995, Journal of immunology.

An experimental model system for HIV-1-induced brain injury.

H. Gendelman, M. Jett, H. Nottet, 1994, Advances in neuroimmunology.

APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro.

J. Paridaen, J. Verhoef, C. Pereira, 2003, The Journal of antimicrobial chemotherapy.

N‐acetyl‐L‐cysteine‐induced up‐regulation of HIV‐1 gene expression in monocyte‐derived macrophages correlates with increased NF‐κB DNA binding activity

M. Visser, J. Verhoef, H. Nottet, 1997, Journal of leukocyte biology.

Cellular aspects of HIV‐1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV‐1 encephalitis

J. Verhoef, L. Boven, H. Nottet, 1997, Journal of leukocyte biology.

HIV-1 Can Persist in Aged Memory CD4+ T Lymphocytes With Minimal Signs of Evolution After 8.3 Years of Effective Highly Active Antiretroviral Therapy

D. Baarle, C. Boucher, N. Vrisekoop, 2009, Journal of acquired immune deficiency syndromes.

Antibody mediated enhancement of HIV‐1 infection of an EBV transformed B cell line is CD4 dependent

M. Visser, J. Verhoef, I. Janse, 1992, European journal of clinical investigation.

Experimental Model Systems for Studies of HIV Encephalitis

H. Gendelman, M. Jett, H. Nottet, 1995 .

Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages.

J. Verhoef, T. van der Bruggen, H. A. Smits, 2001, Journal of neuroimmunology.

The HIV protein Tat-induced induction of in ammatory responses in the brain tissue

M. Toborek, A. Nath, B. Hennig, 2005 .

Enhanced expression of fractalkine in HIV-1 associated dementia

G. Jansen, J. Verhoef, C. Pereira, 2001, Journal of Neuroimmunology.