Gaelen T. Hess

发表

The impact of rare variation on gene expression across tissues

Gao Wang, Mary Goldman, Brian Craft, 2016, Nature.

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

Gaelen T. Hess, A. Kundaje, M. Snyder, 2017, Nature Communications.

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

Gaelen T. Hess, D. Morgens, Kyuho Han, 2017, Nature Biotechnology.

High-Throughput Discovery and Characterization of Human Transcriptional Effectors

Gaelen T. Hess, Nicole V. DelRosso, A. Kundaje, 2020, Cell.

Static and dynamic DNA loops form AP-1 bound activation hubs during macrophage development

Gaelen T. Hess, M. Snyder, D. Spacek, 2017, bioRxiv.

Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements

Michael Wainberg, Anshul Kundaje, Oana Ursu, 2019, bioRxiv.

Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins

Gaelen T. Hess, Michael M. Dubreuil, R. Altman, 2019, eLife.

Orthogonal labeling of M13 minor capsid proteins with DNA to self-assemble end-to-end multiphage structures.

Gaelen T. Hess, Carla P. Guimarães, A. Belcher, 2013, ACS synthetic biology.

Roadmap for the use of base editors to decipher drug mechanism of action

Gaelen T. Hess, M. Mariotti, H. Xi, 2020, PloS one.

Phage Particles of Controlled Length and Genome for In Vivo Targeted Glioblastoma Imaging and Therapeutic Delivery.

Gaelen T. Hess, J. Sarkaria, A. Belcher, 2022, ACS nano.

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

Gaelen T. Hess, K. Garcia, M. Bassik, 2022, bioRxiv.

High-Throughput Discovery and Characterization of Human Transcriptional Effectors

Gaelen T. Hess, A. Kundaje, G. Marinov, 2020, Cell.

SLC19A1 is an importer of the immunotransmitter cGAMP

Gaelen T. Hess, M. Bassik, Lingyin Li, 2019, bioRxiv.

Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7

Gaelen T. Hess, C. Bertozzi, W. Moerner, 2021, Proceedings of the National Academy of Sciences.

Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation

Gaelen T. Hess, C. Bertozzi, W. Moerner, 2020, Proceedings of the National Academy of Sciences.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

Gaelen T. Hess, D. Breslow, D. Morgens, 2017, Nature Genetics.

Static and dynamic DNA loops form AP-1 bound activation hubs during macrophage development

Michael P Snyder, Ido Machol, Erez Lieberman Aiden, 2017, bioRxiv.

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

Gaelen T. Hess, S. Montgomery, Laurent Frésard, 2016, Nature Methods.

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.

Gaelen T. Hess, M. Bassik, M. Maduke, 2020, Molecular cell.

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements

Michael P Snyder, Michael Wainberg, Anshul Kundaje, 2019, Nature Communications.

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.

Gaelen T. Hess, David Yao, Josh Tycko, 2017, Molecular cell.

Translation readthrough mitigation

Gaelen T. Hess, Joshua A. Arribere, A. Fire, 2016, Nature.

A comprehensive portrait of cilia and ciliopathies from a CRISPR-based screen for Hedgehog signaling

Gaelen T. Hess, D. Breslow, D. Morgens, 2017, bioRxiv.

Population and individual-specific regulatory variation in Sardinia

Alexis Battle, John Novembre, Xin Li, 2017, Nature Genetics.

Supplementary Note Tables9-10 track changes

Gaelen T. Hess, D. Breslow, D. Morgens, 2017 .

The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells

Gaelen T. Hess, M. Bassik, M. Maduke, 2020, bioRxiv.

Sortase-Mediated Labeling of M13 Bacteriophage and the Formation of Multi-Phage Structures

Gaelen T. Hess, 2012 .

Cellular binding, motion, and internalization of synthetic gene delivery polymers.

Gaelen T. Hess, Nicole C. Fay, C. Payne, 2007, Biochimica et biophysica acta.

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

Gaelen T. Hess, Lei S. Qi, Lacramioara Bintu, 2023, bioRxiv.

M13 bacteriophage display framework that allows sortase-mediated modification of surface-accessible phage proteins.

Gaelen T. Hess, Carla P. Guimarães, A. Belcher, 2012, Bioconjugate chemistry.

CRISPR-based screen for Hedgehog signaling provides insights into function

Gaelen T. Hess, D. Breslow, D. Morgens, 2018 .

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

Gaelen T. Hess, A. Kundaje, W. Greenleaf, 2017, Nature Communications.

Pathogenic or benign?

Gaelen T. Hess, M. Bassik, Kathy Liu, 2022, Nature Biotechnology.

Static and dynamic DNA loops form AP-1 bound activation hubs during macrophage development

Erez Lieberman Aiden, Gaelen T. Hess, M. Snyder, 2017, bioRxiv.

SLC19A1 is an importer of the immunotransmitter cGAMP

Gaelen T. Hess, M. Bassik, Lingyin Li, 2019, bioRxiv.