Alexis Digman

发表

Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity

M. Aschner, K. Soliman, D. Son, 2021, The Journal of biological chemistry.

Deletion of RE1‐silencing transcription factor in striatal astrocytes exacerbates manganese‐induced neurotoxicity in mice

M. Aschner, D. Son, Eunsook Lee, 2022, Glia.

Astrocytic Yin Yang 1 is critical for murine brain development and protection against apoptosis, oxidative stress, and inflammation

M. Aschner, D. Son, Eunsook Lee, 2022, Glia.

Mechanisms of manganese-induced neurotoxicity and the pursuit of neurotherapeutic strategies

M. Aschner, Eunsook Y. Lee, E. Pajarillo, 2022, Frontiers in Pharmacology.

Manganese Accumulation in the Brain via Various Transporters and Its Neurotoxicity Mechanisms

M. Aschner, K. Soliman, Eunsook Y. Lee, 2020, Molecules.

The role of microglial LRRK2 in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction

M. Aschner, D. Son, Eunsook Y. Lee, 2023, bioRxiv.

The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction

M. Aschner, D. Son, Eunsook Y. Lee, 2023, The Journal of biological chemistry.

The role of microglial LRRK2 kinase in manganese-induced inflammatory neurotoxicity via NLRP3 inflammasome and RAB10-mediated autophagy dysfunction

M. Aschner, D. Son, Eunsook Y. Lee, 2023, The Journal of biological chemistry.

Microglial Sp1 induced LRRK2 upregulation in response to manganese exposure, and 17β-estradiol afforded protection against this manganese toxicity.

D. Son, Eunsook Y. Lee, E. Pajarillo, 2024, Neurotoxicology.