A. Markov

发表

Increasing bioavailability of very poorly water-soluble compounds. A case study of an anti-tumor drug, soloxolon methyl

A. A. Nefedov, A. Ogienko, M. Zenkova, 2019, Journal of Drug Delivery Science and Technology.

Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis

A. Kel, M. Zenkova, N. Salakhutdinov, 2019, Oncotarget.

Asthma and Post-Asthmatic Fibrosis: A Search for New Promising Molecular Markers of Transition from Acute Inflammation to Pulmonary Fibrosis

A. Markov, I. Savin, Marina A Zenkova, 2022, Biomedicines.

Synthesis of novel 2-cyano substituted glycyrrhetinic acid derivatives as inhibitors of cancer cells growth and NO production in LPS-activated J-774 cells.

V. Vlassov, M. Zenkova, N. Salakhutdinov, 2014, Bioorganic & medicinal chemistry.

Novel Epoxides of Soloxolone Methyl: An Effect of the Formation of Oxirane Ring and Stereoisomerism on Cytotoxic Profile, Anti-Metastatic and Anti-Inflammatory Activities In Vitro and In Vivo

M. Zenkova, N. Salakhutdinov, O. Salomatina, 2022, International journal of molecular sciences.

Novel Soloxolone Amides as Potent Anti-Glioblastoma Candidates: Design, Synthesis, In Silico Analysis and Biological Activities In Vitro and In Vivo

M. Zenkova, N. Salakhutdinov, A. Ilyina, 2022, Pharmaceuticals.

Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy

V. Vlassov, D. Stetsenko, M. Zenkova, 2022, Cancers.

Bovine Pancreatic RNase A: An Insight into the Mechanism of Antitumor Activity In Vitro and In Vivo

M. Zenkova, N. Mironova, O. V. Markov, 2022, Pharmaceutics.

Synthesis and biological activity of novel deoxycholic acid derivatives.

I. I. Popadyuk, A. Shernyukov, M. Zenkova, 2015, Bioorganic & medicinal chemistry.

siRNA-Mediated Timp1 Silencing Inhibited the Inflammatory Phenotype during Acute Lung Injury

I. V. Chernikov, V. Vlassov, E. Chernolovskaya, 2023, International journal of molecular sciences.

Synthesis and Pro-Apoptotic Activity of Novel Glycyrrhetinic Acid Derivatives

V. Vlassov, M. Zenkova, N. Salakhutdinov, 2011, Chembiochem : a European journal of chemical biology.

Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position

I. I. Popadyuk, M. Zenkova, N. Salakhutdinov, 2017, Steroids.

Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activity.

I. I. Popadyuk, M. Zenkova, N. Salakhutdinov, 2017, Bioorganic & medicinal chemistry letters.

Modulation of Tumour-Related Signaling Pathways by Natural Pentacyclic Triterpenoids and their Semisynthetic Derivatives.

M. Zenkova, E. Logashenko, A. Markov, 2017, Current medicinal chemistry.

Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice

M. Zenkova, N. Salakhutdinov, O. Salomatina, 2020, Molecules.

Protective effect of soloxolone derivatives in carrageenan- and LPS-driven acute inflammation: Pharmacological profiling and their effects on key inflammation-related processes.

N. Salakhutdinov, O. Salomatina, A. Markov, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Uncovering the anti-angiogenic effect of semisynthetic triterpenoid CDDO-Im on HUVECs by an integrated network pharmacology approach

M. Zenkova, A. Ilyina, A. Markov, 2021, Comput. Biol. Medicine.

Cyano Enone-Bearing Triterpenoid Soloxolone Methyl Inhibits Epithelial-Mesenchymal Transition of Human Lung Adenocarcinoma Cells In Vitro and Metastasis of Murine Melanoma In Vivo

M. Zenkova, N. Salakhutdinov, O. Salomatina, 2020, Molecules.

Novel 3′-Substituted-1′,2′,4′-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo

I. I. Popadyuk, M. Zenkova, N. Salakhutdinov, 2020, International journal of molecular sciences.

Novel Glycyrrhetinic Acid Derivative Soloxolone Methyl Inhibits the Inflammatory Response and Tumor Growth in vivo

M. Zenkova, E. Logashenko, A. Markov, 2018, Molecular Biology.

Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation

M. Zenkova, D. Warszycki, N. Salakhutdinov, 2017, Scientific Reports.

Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus

D. Pyshnyi, M. Kupryushkin, M. Zenkova, 2019, Russian Journal of Bioorganic Chemistry.

Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning

V. Mitkevich, M. Zenkova, O. Ilinskaya, 2020, Biomolecules.

Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential

I. I. Popadyuk, M. Zenkova, N. Salakhutdinov, 2019, Molecules.

Dual Effect of Soloxolone Methyl on LPS-Induced Inflammation In Vitro and In Vivo

M. Zenkova, N. Salakhutdinov, O. Salomatina, 2020, International journal of molecular sciences.

NORMALIZATION OF THE METABOLISM OF ESSENTIAL FATTY ACIDS OF PHOSOLIPIDS OF THE LIVER OF RATS RECEIVED WITH PALM OIL ON THE BACKGROUND OF DISBIOSIS BY THE PHYTOPREPARATION “KVERTULIN”

A. Markov, A. Levitsky, T. Pupin, 2021, Fitoterapia.

The Indirect Methods of Conversion Monitoring Throughout Polymerization Processes in Bulk

R. Y. Kulishenko, A. Markov, Yuri P. Yulenets, 2021 .

Core genes involved in the regulation of acute lung injury and their association with COVID-19 and tumor progression: A bioinformatics and experimental study

M. Zenkova, A. Markov, I. Savin, 2021, PloS one.

Identification of Novel Core Genes Involved in Malignant Transformation of Inflamed Colon Tissue Using a Computational Biology Approach and Verification in Murine Models

A. Markov, I. Savin, A. Sen’kova, 2023, International journal of molecular sciences.

Symmetric lipophilic polyamines exhibiting antitumor activity.

I. V. Chernikov, M. Zenkova, M. Maslov, 2022, Bioorganic & medicinal chemistry.

Evaluation of the Antitumor Potential of Soloxolone Tryptamide against Glioblastoma Multiforme Using in silico, in vitro, and in vivo Approaches

M. Zenkova, A. Ilyina, A. Markov, 2023, Biochemistry (Moscow).

Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation

M. Zenkova, D. Warszycki, N. Salakhutdinov, 2017, Scientific Reports.

Soloxolone Methyl Reduces the Stimulatory Effect of Leptin on the Aggressive Phenotype of Murine Neuro2a Neuroblastoma Cells via the MAPK/ERK1/2 Pathway

I. V. Chernikov, N. Salakhutdinov, O. Salomatina, 2023, Pharmaceuticals.

The Nexus of Inflammation-Induced Epithelial-Mesenchymal Transition and Lung Cancer Progression: A Roadmap to Pentacyclic Triterpenoid-Based Therapies

A. Markov, M. Zenkova, Kirill V. Odarenko, 2023, International journal of molecular sciences.

Novel Glycyrrhetinic Acid Derivative Soloxolone Methyl Inhibits the Inflammatory Response and Tumor Growth in vivo

E. Logashenko, A. Markov, M. Zenkova, 2018, Molecular Biology.

A Novel 3-meta-Pyridine-1,2,4-oxadiazole Derivative of Glycyrrhetinic Acid as a Safe and Promising Candidate for Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells

I. V. Chernikov, O. Salomatina, A. Markov, 2023, ACS omega.

Soloxolone N-3-(Dimethylamino)propylamide Restores Drug Sensitivity of Tumor Cells with Multidrug-Resistant Phenotype via Inhibition of P-Glycoprotein Efflux Function

O. Salomatina, A. Markov, M. Zenkova, 2024, Molecules.