Wenjie Wang

发表

Evidence for Inhibition of Topoisomerase 1A by Gold(III) Macrocycles and Chelates Targeting Mycobacterium tuberculosis and Mycobacterium abscessus

L. Shaw, Y. Tse‐Dinh, Rashmi Gupta, 2018, Antimicrobial Agents and Chemotherapy.

Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents

W. Reinhold, Y. Pommier, Y. Tse‐Dinh, 2019, bioRxiv.

Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.

Brice A P Wilson, Y. Pommier, K. Gustafson, 2020, Journal of the American Chemical Society.

Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1

Y. Pommier, J. Tropea, T. Burke, 2022, Frontiers in Chemistry.

Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC).

Y. Pommier, Yilun Sun, Shar-yin N. Huang, 2020, DNA repair.

The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors.

Y. Pommier, K. Agama, Lin-Kun An, 2021, Bioorganic chemistry.

Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity.

Y. Pommier, Fang Wang, K. Agama, 2022, Bioorganic chemistry.

Discovery of 4-alkoxy-2-aryl-6,7-dimethoxyquinolines as a new class of topoisomerase I inhibitors endowed with potent in vitro anticancer activity.

Y. Pommier, K. Agama, Wagdy M. Eldehna, 2021, European journal of medicinal chemistry.

Recent Advances in Use of Topoisomerase Inhibitors in Combination Cancer Therapy.

Y. Tse‐Dinh, Wenjie Wang, 2019, Current topics in medicinal chemistry.

PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation

Y. Pommier, L. Jenkins, J. Pascal, 2021, Nature Communications.

Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer.

Y. Pommier, K. Agama, Lin-Kun An, 2021, Journal of medicinal chemistry.

Synthesis and Biological Activities of 11‐ and 12‐Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl‐DNA Phosphodiesterase 1 Inhibitors

Y. Pommier, Fang Wang, K. Agama, 2023, ChemMedChem.

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites†

Y. Pommier, J. Tropea, D. Waugh, 2021, Chemical science.

Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification

Y. Pommier, J. Tropea, T. Burke, 2023, RSC chemical biology.

Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis

Haifeng Zhang, Qihua Zhu, Ming-Fu Cheng, 2023, Bioorganic & Medicinal Chemistry.

Mechanism and resistance for antimycobacterial activity of a fluoroquinophenoxazine compound

P. Tiwari, A. Uhlemann, F. Leng, 2018, bioRxiv.