Jill Nunez

发表

Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer.

F. Lombardo, Alice T. Loo, L. Hamann, 2017, Journal of medicinal chemistry.

Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.

F. Lombardo, L. Hamann, T. Abrams, 2018, Journal of medicinal chemistry.

Discovery of a Brain Penetrant ATP-competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS disorders.

D. Curtis, F. Lombardo, Christopher J. Wilson, 2020, Journal of medicinal chemistry.

Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC.

M. Glick, L. Hamann, Yipin Lu, 2017, Journal of medicinal chemistry.

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy.

J. D. Clark, J. McKew, W. Abraham, 2008, Bioorganic & medicinal chemistry.

One-pot reductive amination and Suzuki-Miyaura cross-coupling of formyl aryl and heteroaryl MIDA boronates in array format.

L. Hamann, Jonathan E. Grob, Jill Nunez, 2011, The Journal of organic chemistry.

Regioselective synthesis and slow-release Suzuki-Miyaura cross-coupling of MIDA boronate-functionalized isoxazoles and triazoles.

L. Hamann, Jonathan E. Grob, Jill Nunez, 2011, The Journal of organic chemistry.

A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

William Egan, W. Egan, B. Lagu, 2011 .

Regioselective Synthesis and Slow-Release Suzuki—Miyaura Cross-Coupling of MIDA Boronate-Functionalized Isoxazoles and Triazoles.

L. Hamann, Jonathan E. Grob, Jill Nunez, 2012 .

Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists.

A. Bose, S. Peukert, R. Jain, 2014, ACS medicinal chemistry letters.

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.

J. McKew, T. Mansour, J. Xiang, 2008, Journal of medicinal chemistry.

Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes.

D. Curtis, Christopher J. Wilson, P. Furet, 2023, Journal of Medicinal Chemistry.