Rao V. Kalla

发表

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 and a variant of concern in ferrets

R. Plemper, Julien Sourimant, R. Mackman, 2021 .

Recent developments in A2B adenosine receptor ligands.

P. Baraldi, M. A. Tabrizi, J. Zablocki, 2009, Handbook of experimental pharmacology.

Progress in the discovery of selective, high affinity A2B adenosine receptor antagonists as clinical candidates

J. Zablocki, Rao V. Kalla, Rao V Kalla, 2008, Purinergic Signalling.

Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists.

David A. Lustig, Xiaofen Li, E. Elzein, 2006, Bioorganic & medicinal chemistry letters.

The discovery of a selective, high affinity A(2B) adenosine receptor antagonist for the potential treatment of asthma.

D. Zeng, N. Chu, K. Leung, 2005, Bioorganic & medicinal chemistry letters.

Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice

R. Baric, T. Sheahan, R. Mackman, 2022, Science Translational Medicine.

Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.

R. Baric, T. Sheahan, R. Mackman, 2021, bioRxiv.

Selective, high affinity A(2B) adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl)xanthines.

Xiaofen Li, E. Elzein, D. Zeng, 2008, Bioorganic & medicinal chemistry letters.

Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.

M. Desai, Xiaofen Li, Tetsuya Kobayashi, 2016, Journal of medicinal chemistry.

N6-Cycloalkyl-2-substituted adenosine derivatives as selective, high affinity adenosine A1 receptor agonists.

Xiaofen Li, E. Elzein, D. Zeng, 2007, Bioorganic & medicinal chemistry letters.

A2B adenosine receptor antagonists and their potential indications

E. Elzein, J. Zablocki, Rao V. Kalla, 2006 .

Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases.

David A. Lustig, Xiaofen Li, E. Elzein, 2008, Journal of medicinal chemistry.

Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets

R. Plemper, Julien Sourimant, R. Mackman, 2021, Nature Communications.

Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.

Xiaofen Li, E. Elzein, D. Zeng, 2006, Journal of medicinal chemistry.