A. Nezami

发表

Crystal Structure of a Complex between Amino and Carboxy Terminal Fragments of mDia1: Insights into Autoinhibition of Diaphanous-Related Formins

M. Eck, F. Poy, A. Toms, 2010, PloS one.

Structure of the autoinhibitory switch in formin mDia1.

M. Eck, F. Poy, A. Nezami, 2006, Structure.

High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor.

Jun Liu, D. Goldberg, E. Freire, 2003, Biochemistry.

Isothermal titration calorimetry

A. Velázquez‐Campoy, M. Straume, E. Freire, 1990 .

Isothermal Titration Calorimetry

A. Velázquez‐Campoy, E. Freire, E. Freire, 2004, Current protocols in cell biology.

Tubulin binding, protein-bound conformation in solution, and antimitotic cellular profiling of noscapine and its derivatives.

Tiansheng Wang, B. Eustace, Á. Canales, 2012, Journal of medicinal chemistry.

Identification of novel HSP90α/β isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease.

Beth A. Fleck, L. Goulet, J. Ernst, 2014, Journal of medicinal chemistry.

Search for substrate‐based inhibitors fitting the S2′ space of malarial aspartic protease plasmepsin II

E. Freire, Y. Kiso, Tooru Kimura, 2004, Journal of peptide science : an official publication of the European Peptide Society.

Design of inhibitors against HIV, HTLV-I, and Plasmodium falciparum aspartic proteases

E. Freire, Y. Kiso, Tooru Kimura, 2004, Biological chemistry.

Preclinical Activity of VX-787, a First-in-Class, Orally Bioavailable Inhibitor of the Influenza Virus Polymerase PB2 Subunit

M. Murcko, P. Charifson, A. Kwong, 2014, Antimicrobial Agents and Chemotherapy.

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2.

M. Murcko, F. Maltais, P. Charifson, 2014, Journal of medicinal chemistry.

The integration of genomic and structural information in the development of high affinity plasmepsin inhibitors.

E. Freire, A. Nezami, 2002, International journal for parasitology.

Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.

E. Freire, I. Luque, Y. Kiso, 2002, Biochemistry.

QSAR study of some 5-methyl/trifluoromethoxy- 1H-indole-2,3-dione-3-thiosemicarbazone derivatives as anti-tubercular agents

M. Shahlaei, A. Fassihi, A. Nezami, 2009, Research in pharmaceutical sciences.

Transient State Kinetics of Enzyme IICBGlc, a Glucose Transporter of the Phosphoenolpyruvate Phosphotransferase System of Escherichia coli

S. Roseman, N. Meadow, Regina S. Savtchenko, 2005, Journal of Biological Chemistry.

Isothermal Titration Calorimetry

A. Velázquez‐Campoy, E. Freire, S. Muzammil, 2004 .

Isothermal titration calorimetry.

A. Velázquez‐Campoy, E. Freire, S. Muzammil, 2004, Current Protocols in Cell Biology.

Evaluation of Malarial Protease Plasmepsin Inhibitors Containing Hydroxymethylcarbonyl Isostere

E. Freire, Y. Kiso, Tooru Kimura, 2006 .

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2.

M. Murcko, F. Maltais, P. Charifson, 2014, Journal of medicinal chemistry.