J. Ling

发表

Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects

P. German, A. Mathias, D. Brainard, 2017, Antimicrobial Agents and Chemotherapy.

Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 1: Establishing Induction Relationships Using Ascending Dose Rifampin

A. Mathias, B. Kearney, B. Kirby, 2018, Clinical pharmacology and therapeutics.

Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder

C. Tannenbaum, G. Kay, D. Staskin, 2010, International journal of clinical practice.

Phase 1 First‐in‐Human, Single‐ and Multiple‐Ascending Dose, and Food Effect Studies to Assess the Safety, Tolerability, and Pharmacokinetics of Presatovir for the Treatment of Respiratory Syncytial Virus Infection

S. Lewis, R. Mackman, P. German, 2018, Journal of clinical pharmacology.

Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine

A. Mathias, B. Kearney, B. Kirby, 2018, Clinical pharmacology and therapeutics.

Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor

P. German, A. Mathias, R. Humeniuk, 2021, Clinical Pharmacokinetics.

An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer.

P. German, B. Kearney, T. Tarnowski, 2020, Analytical biochemistry.

Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID‐19, in Healthy Subjects

P. German, A. Mathias, R. Humeniuk, 2020, Clinical and translational science.

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite—Resolution for Clinical Development

M. Warr, R. Subramanian, Y. Xin, 2018, Drug Metabolism and Disposition.

Clinical targeting of HIV capsid protein with a long-acting small molecule

J. R. Somoza, W. Sundquist, Xiaohong Liu, 2020, Nature.

Lack of clinically important PK interaction between coformulated ledipasvir/sofosbuvir and rilpivirine/emtricitabine/tenofovir alafenamide

B. Kearney, H. Cao, J. Flaherty, 2017, Pharmacology research & perspectives.

TROSPIUM CHLORIDE IS UNDETECTABLE IN THE OLDER HUMAN CENTRAL NERVOUS SYSTEM

C. Tannenbaum, G. Kay, D. Staskin, 2010, Journal of the American Geriatrics Society.

P176 Clinical pharmacology of the HIV integrase strand transfer inhibitor bictegravir

B. Kearney, Xuelian Wei, E. Quirk, 2017 .

Pharmacokinetics, Safety, and Tolerability of Selonsertib, an Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitor, Following First-in-Human Single and Multiple Ascending Doses in Healthy Subjects

A. Mathias, Saili Yi, C. Nelson, 2020, Clinical Pharmacokinetics.

Safety, Pharmacokinetics and Pharmacodynamics of Selgantolimod, an Oral Toll-Like Receptor 8 Agonist: A Phase Ia Study in Healthy Subjects

R. Mackman, A. Gaggar, S. Fletcher, 2020, Antiviral therapy.

The Drug–Drug Interaction Profile of Presatovir

Y. Xin, J. Chien, J. Silverman, 2018, Journal of clinical pharmacology.

Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection

Y. Lai, Jianhong Wang, Heather Zhang, 2022, Xenobiotica; the fate of foreign compounds in biological systems.

A Thorough QT Study to Evaluate the Effects of Supratherapeutic Doses of Ledipasvir on the QTc Interval in Healthy Subjects

P. German, A. Mathias, D. Brainard, 2018, Clinical pharmacology in drug development.

Pharmacokinetics of Tenofovir Alafenamide When Coadministered With Other HIV Antiretrovirals

M. Das, R. Begley, B. Kearney, 2018, Journal of acquired immune deficiency syndromes.