D. Marquess

发表

Novel heterodimer antibiotics: a review of recent patent literature.

D. Long, D. Marquess, 2009, Future medicinal chemistry.

A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma.

J. Shaw, Lan Jiang, D. Long, 2013, Bioorganic & medicinal chemistry letters.

Recent Advances in Discovery and Development of Medicines for the Treatment of Secretory Diarrhea in the Developing World

D. Marquess, 2011 .

The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor

K. Tomooka, D. B. Rawlins, M. Natchus, 1997 .

A multivalent approach to the design and discovery of orally efficacious 5-HT4 receptor agonists.

S. D. Turner, J. Shaw, S. Choi, 2009, Journal of medicinal chemistry.

Exploring the Positional Attachment of Glycopeptide/β-lactam Heterodimers

S. Choi, J. Judice, K. Krause, 2008, The Journal of Antibiotics.

Discovery of TD-8954, a clinical stage 5-HT(4) receptor agonist with gastrointestinal prokinetic properties.

J. Shaw, R. Vickery, D. Long, 2013, Bioorganic & medicinal chemistry letters.

Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: clinical compound TD-2749.

J. Shaw, S. Choi, R. Vickery, 2012, Bioorganic & medicinal chemistry letters.

The in vitro pharmacological profile of TD-5108, a selective 5-HT4 receptor agonist with high intrinsic activity

J. Shaw, R. Vickery, J. A. Smith, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

An octameric carbopeptoid; secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates

R. Aplin, T. Claridge, D. Long, 1999 .

From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates

T. Claridge, D. Long, Martin D. Smith, 1999 .

Discovery, oral pharmacokinetics and in vivo efficacy of velusetrag, a highly selective 5-HT(4) receptor agonist that has achieved proof-of-concept in patients with chronic idiopathic constipation.

S. D. Turner, J. Shaw, S. Choi, 2012, Bioorganic & medicinal chemistry letters.

Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids

T. Claridge, D. Long, Martin D. Smith, 1998 .

A solid phase approach to oligomers of carbohydrate amino-acids: Secondary structure in a trimeric furanose carbopeptoid

T. Claridge, D. Long, Martin D. Smith, 1998 .

Open-chain acetonides of D-galactono-1,4-lactone as starting materials for pyrrolidines, azepanes and 5-azidomethyltetrahydrofuran-2-carboxylates: monomers for polyhydroxylated nylon and for tetrahydrofuran carbopeptoids

D. Long, G. Fleet, N. Asano, 1999 .

Potential intermediates for incorporation of polyhydroxylated prolines into combinatorial libraries

D. Winkler, D. Watkin, D. Long, 1998 .

Kinetic and thermodynamic azides from α-triflates of γ-lactones: intermediates for the incorporation of polyhydroxylated D- and L-α-aminoacids into combinatorial libraries

B. G. Davis, D. Watkin, D. Long, 1996 .

Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis .1. Synthesis of tripeptide probes

A. Pitt, J. Baldwin, R. Adlington, 1996 .

Absence of secondary structure in a carbopeptoid tetramer of a trans-5-aminomethyl-tetrahydrofuran-2-carboxylate

T. Claridge, D. Long, Martin D. Smith, 1999 .

The Pinene Path to Taxanes. 6. A Concise Stereocontrolled Synthesis of Taxol

M. Natchus, P. Wender, P. Floreancig, 1997 .

1,4-Benzodiazepin-2-one derived neurokinin-1 receptor antagonists

M. Congreve, P. Ward, A. B. Hawcock, 1997 .

Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 2. Incubation and interpretation

A. Pitt, J. Baldwin, R. Adlington, 1996 .

Senescent cells: an emerging target for diseases of ageing

D. Baker, Rémi-Martin Laberge, J. Deursen, 2017, Nature Reviews Drug Discovery.

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.

Frédérick A. Mallette, C. Yohn, C. Beauséjour, 2021, Cell metabolism.

Comparison of the pharmacological properties of rat Na(V)1.8 with rat Na(V)1.2a and human Na(V)1.5 voltage-gated sodium channel subtypes using a membrane potential sensitive dye and FLIPR.

R. Vickery, S. Amagasu, C. Gee, 2004, Receptors & channels.

The 5‐HT4 receptor agonist, tegaserod, is a potent 5‐HT2B receptor antagonist in vitro and in vivo

R. Vickery, T. Pulido-Rios, J. A. Smith, 2004, British journal of pharmacology.

Discovery of TD-0212, an Orally Active Dual Pharmacology AT1 Antagonist and Neprilysin Inhibitor (ARNI).

J. Budman, S. Choi, R. M. Mckinnell, 2018, ACS medicinal chemistry letters.

The in vivo gastrointestinal activity of TD-5108, a selective 5-HT4 receptor agonist with high intrinsic activity

J. Taylor, J. Shaw, J. A. Smith, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Comparison of the pharmacological properties of rat Na(V)1.8 with rat Na(V)1.2a and human Na(V)1.5 voltage-gated sodium channel subtypes using a membrane potential sensitive dye and FLIPR.

R. Vickery, S. Amagasu, C. Gee, 2004, Receptors & channels.