Xicheng Sun

发表

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

T. Jarvis, M. Gonzalez-Juarrero, M. Jackson, 2018, Front. Microbiol..

Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation

S. Mutka, M. Suniga, G. Rosenthal, 2014, BMC Pulmonary Medicine.

New agents for Clostridium difficile-associated disease

I. Critchley, J. Guiles, Xicheng Sun, 2008, Expert opinion on investigational drugs.

A convenient synthesis of cyclic peptides as regioselectively addressable functionalized templates (RAFT)

M. Mutter, P. Dumy, I. Eggleston, 1995 .

Structure-activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: carboxamide modification.

S. Mutka, D. Colagiovanni, G. Rosenthal, 2012, Bioorganic & medicinal chemistry letters.

Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase.

G. Rosenthal, L. Green, J. P. Richards, 2012, Biochemistry.

Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities.

S. Mutka, D. Colagiovanni, G. Rosenthal, 2011, Bioorganic & medicinal chemistry letters.

Structure-activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: pyrrole regioisomers and propionic acid replacement.

S. Mutka, D. Colagiovanni, G. Rosenthal, 2011, Bioorganic & medicinal chemistry letters.

Discovery of s-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases.

S. Mutka, D. Colagiovanni, G. Rosenthal, 2011, ACS medicinal chemistry letters.

Recent Development in the Treatment of Clostridium difficile Associated Disease (CDAD)

N. Janjić, J. Guiles, Xicheng Sun, 2008 .

Discovery of benzothiazole amides as potent antimycobacterial agents.

T. Jarvis, U. Ochsner, Joshua A Day, 2018, Bioorganic & medicinal chemistry letters.

Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3.

G. Lamichhane, T. Jarvis, H. Zgurskaya, 2022, Tuberculosis.

Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III.

F. Dean, N. Janjić, U. Ochsner, 2009, Bioorganic & medicinal chemistry letters.

Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents

Ian Critchley, Nebojsa Janjic, T. Jarvis, 2007, Expert opinion on investigational drugs.

Potency of the novel PolC DNA polymerase inhibitor CRS0540 in a disseminated Listeria monocytogenes intracellular hollow-fibre model

T. Jarvis, U. Ochsner, Joshua A Day, 2022, The Journal of antimicrobial chemotherapy.

On the Stacking of β -Rings: The solution self-association behavior of two partially N-methylated cyclo(hexaleucines)

Xicheng Sun, Gian Paolo Lorenzi, G. P. Lorenzi, 1994 .

A structural two-ring version of a tubular stack ofβ-rings in crystals of a cyclic D,L-hexapeptide

Angela Lombardi, Michele Saviano, A. Lombardi, 1994 .

Oral S-Nitrosoglutathione Reductase Inhibitors Attenuate Pulmonary Inflammation And Decrease Airspace Enlargement In Experimental Models Of Chronic Obstructive Pulmonary Disease

S. Mutka, G. Rosenthal, D. Drolet, 2011, ATS 2011.

Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III.

F. Dean, N. Janjić, U. Ochsner, 2009, Bioorganic & medicinal chemistry letters.