D. Vardeman

发表

Correlation between the sensitivity of tumors to treatment with CZ48 and local concentrations of the active metabolite CPT within the tumors.

B. Giovanella, J. Mendoza, Z. Cao, 2013, Biomedical reports.

Enhanced lactone stability of CZ48 in blood correlates to its lack of toxicity in mice.

B. Giovanella, Max Zhan, Z. Cao, 2013, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Growth inhibition of human cancer metastases by camptothecins in newly developed xenograft models.

B. Giovanella, M. Potměšil, J. Stehlin, 1995, Cancer research.

Metabolic Difference of CZ48 in Human and Mouse Liver Microsomes

B. Giovanella, A. Dejesus, Z. Cao, 2012, International journal of molecular sciences.

Sulfuric Acid Catalyzed Preparation of Alkyl and Alkenyl Camptothecin Ester Derivatives and Antitumor Activity against Human Xenografts Grown in Nude Mice

B. Giovanella, A. Kozielski, Z. Cao, 2012 .

Development and validation of a reverse-phase HPLC with fluorescence detector method for simultaneous determination of CZ48 and its active metabolite camptothecin in mouse plasma.

B. Giovanella, Z. Cao, Xing Liu, 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Structure‐Activity Relationship of Alkyl Camptothecin Esters

B. Giovanella, J. Liehr, J. Stehlin, 2000, Annals of the New York Academy of Sciences.

Heterotransplantation of human breast carcinomas in nude mice. Correlation between successful heterotransplants, poor prognosis and amplification of the her‐2/neu oncogene

A. Ullrich, D. Taylor, H. Gary, 1991, International journal of cancer.

Desmoplastic small round cell tumor (DSRCT) xenografts and tissue culture lines: Establishment and initial characterization

B. Giovanella, J. Mendoza, D. Vardeman, 2013, Oncology letters.

Alkyl esters of camptothecin and 9-nitrocamptothecin: synthesis, in vitro pharmacokinetics, toxicity, and antitumor activity.

B. Giovanella, J. Stehlin, A. Kozielski, 1998, Journal of medicinal chemistry.

Sensitivity of camptothecin-resistant human leukemia cells and tumors to anticancer drugs with diverse mechanisms of action.

P. Pantazis, B. Giovanella, J. Mendoza, 1995, Leukemia research.

Efficacy of camptothecin congeners in the treatment of human breast carcinoma xenografts.

P. Pantazis, B. Giovanella, P Pantazis, 1993, Oncology research.

Anticancer activity of new haloalkyl camptothecin esters against human cancer cell lines and human tumor xenografts grown in nude mice.

C. Zhan, B. Giovanella, J. Mendoza, 2012, Anti-Cancer Agents in Medicinal Chemistry.

Crystalline camptothecin-20(S)-O-propionate hydrate: a novel anticancer agent with strong activity against 19 human tumor xenografts.

B. Giovanella, A. Kozielski, Z. Cao, 2009, Cancer research.

Synthesis and antitumor activity of aromatic camptothecin esters.

B. Giovanella, J. Mendoza, A. Dejesus, 2008, International journal of molecular medicine.

Protocols for the Treatment of Human Tumor Xenografts with Camptothecins

B. Giovanella, J. Stehlin, N. Harris, 1996, Annals of the New York Academy of Sciences.

Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan).

B. Giovanella, J. Stehlin, A. Kozielski, 2002, International journal of oncology.

Growth Inhibition of Human Cancer Metastases by Camptothecins in Newly Developed Xenograft Models 1

B. Giovanella, M. Potměšil, J. Stehlin, 2006 .

Correlation of cytotoxicity with elimination of iodine-125 from nude mice inoculated with prelabeled human melanoma cells.

B. Giovanella, J. Stehlin, J. Mendoza, 1984, Journal of the National Cancer Institute.

Studies of time/dose intensity in treatment of human cancer xenografts with camptothecin analogues

B. Giovanella, M. Potměšil, J. Stehlin, 1994 .