S. Takeda

发表

Augmentation of the chemotherapeutic effectiveness of UFT, a combination of tegafur [1-(2-tetrahydrofuryl)-5-fluorouracil] with uracil, by oral l-leucovorin.

A. Fujioka, H. Okabe, K. Nakano, 1997, Anticancer research.

Antitumor activity and low intestinal toxicity of S-1, a new formulation of oral tegafur, in experimental tumor models in rats

J. Uchida, K. Nakano, A. Mita, 1996, Cancer Chemotherapy and Pharmacology.

Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats.

A. Fujioka, M. Fukushima, J. Uchida, 1996, Cancer research.

Pretreatment with S-1, an oral derivative of 5-fluorouracil, enhances gemcitabine effects in pancreatic cancer xenografts.

Y. Takeda, M. Monden, K. Dono, 2008, Anticancer research.

[Significance of measuring 5-fluorouracil incorporated into RNA of tumor tissue as a parameter for the antitumor activity of 5-fluorouracil and its analogs].

J. Uchida, Y. Umeno, S. Takeda, 1992, Gan to kagaku ryoho. Cancer & chemotherapy.

Prolongation of survival period and improvement of cancer cachexia by long-term administration of UFT.

A. Fujioka, J. Uchida, K. Nakano, 1996, Cancer letters.

Postsurgical oral administration of uracil and tegafur inhibits progression of micrometastasis of human breast cancer cells in nude mice.

A. Fujioka, M. Kurosumi, R. Dickson, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Interaction of DP-TAT-59, an active metabolite of new triphenylethylene-derivative (TAT-59), with estrogen receptors

T. Hirose, K. Wierzba, Yuji Yamada, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Schedule-dependent Therapeutic Effects of Gemcitabine Combined with Uracil-Tegafur in a Human Pancreatic Cancer Xenograft Model

M. Monden, K. Dono, H. Nagano, 2006, Pancreas.

TAT-59, a new triphenylethylene derivative with antitumor activity against hormone-dependent tumors.

Y. Sugimoto, R. Yamasaki, K. Wierzba, 1990, European journal of cancer.

Antitumor activity of diterpenoids, trichorabdals A, B, and C, and the related compounds: synergism of two active sites.

M. Node, M. Sai, E. Fujita, 1983, Chemical & pharmaceutical bulletin.

Terpenoids. LIII. Antitumor activity of trichorabdals and related compounds.

M. Node, M. Sai, E. Fujita, 1989, Chemical & pharmaceutical bulletin.

New antifungal 1,2,4-triazoles with difluoro(substituted sulfonyl)methyl moiety.

K. Maebashi, K. Ishida, M. Matsumoto, 2001, Chemical & pharmaceutical bulletin.

Antitumor agents. II: Regio- and stereospecific syntheses of 1-beta-alkyl-1-desoxypodophyllotoxin derivatives and biological activity.

K. Wierzba, T. Terada, T. Kobunai, 1993, Chemical & pharmaceutical bulletin.

Antitumor activities of harringtonine and homoharringtonine, cephalotaxus alkaloids which are active principles from plant by intraperitoneal and oral administration.

N. Unemi, K. Kitazato, S. Takeda, 1982, Journal of pharmacobio-dynamics.

STUDIES ON COMBINATION THERAPY WITH 1-(TETRAHYDRO-2-FURANYL)-5-FLUOROURACIL PLUS URACIL. I

Y. Kawaguchi, N. Unemi, S. Takeda, 1981 .

Studies on Combination Therapy with 1-(Tetrahydro-2-Furanyl)-5-Fluorouracil Plus Uracil-2-Effects of Uracil on In Vitro Metabolisms of 1-(Tetrahydro-2-furanyl)-5-fluorouracil and 5-Fluorouracil

N. Unemi, S. Takeda, 1981 .

Antitumor activity of FTC-092, a masked 5-trifluoromethyl-2′-deoxyuridine derivative

Y. Wataya, J. Uchida, Yuji Yamada, 2004, Cancer Chemotherapy and Pharmacology.

Studies on antitumor agents. 8. Antitumor activities of O-alkyl derivatives of 2'-deoxy-5-(trifluoromethyl)uridine and 2'-deoxy-5-fluorouridine.

H. Matsumoto, N. Unemi, S. Takeda, 1989, Journal of medicinal chemistry.

Studies on antitumor agents. VII. Antitumor activities of O-alkoxyalkyl derivatives of 2'-deoxy-5-trifluoromethyluridine.

H. Matsumoto, N. Unemi, S. Takeda, 1987, Chemical and pharmaceutical bulletin.

Studies on antitumor agents. VI. Syntheses and antitumor activities of acyl derivatives of 2'-deoxy-5-trifluoromethyluridine.

T. Terada, H. Matsumoto, N. Unemi, 1987, Chemical and pharmaceutical bulletin.

Studies on antitumor agents. IV. Syntheses and antitumor activities of compounds related to 1-(tetrahydro-2-furanyl)-5-fluorouracil metabolites.

S. Takeda, M. Yasumoto, S. Hashimoto, 1982, Chemical & pharmaceutical bulletin.

Potentiation of the antitumor activity of 5-trifluoromethyl-2′-deoxyuridine by the use of depot forms of the parent compound

Y. Wataya, K. Wierzba, Yuji Yamada, 2004, Cancer Chemotherapy and Pharmacology.

Studies on Antitumor Agents. Part 6. Syntheses and Antitumor Activities of Acyl Derivatives of 2′-Deoxy-5-trifluoromethyluridine.

T. Terada, H. Matsumoto, N. Unemi, 1987 .

Antitumor agents. I. DNA topoisomerase II inhibitory activity and the structural relationship of podophyllotoxin derivatives as antitumor agents.

K. Wierzba, T. Terada, T. Kobunai, 1992, Chemical & pharmaceutical bulletin.

Terpenoids. L: Antitumor activity of diterpenoids from Rabdosia shikokiana var. occidentalis

K. Fuji, M. Node, E. Fujita, 1985 .

Preclinical antitumor efficacy of S-1: a new oral formulation of 5-fluorouracil on human tumor xenografts.

A. Fujioka, M. Fukushima, J. Uchida, 1998, International journal of oncology.

Effect of 1,3,3,5,5-pentaziridino-1-thia-2,4,6-triaza-3,5-diphosphorine-1-oxide, a new antitumor agent with inorganic ring, on various experimental tumors.

N. Unemi, K. Kitazato, S. Takeda, 1982, Journal of pharmacobio-dynamics.

Menogaril, an Anthracycline Compound with a Novel Mechanism of Action: Cellular Pharmacology

Y. Sugimoto, K. Wierzba, Yuji Yamada, 1990, Japanese journal of cancer research : Gann.

[Experimental study of the effect of combined treatment of UFT with CDDP on human solid tumor-xenografts in nude mice].

K. Nakano, Y. Yamada, S. Oie, 1990, Gan to kagaku ryoho. Cancer & chemotherapy.

Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.

Y. Sugimoto, K. Wierzba, T. Terada, 1993, Journal of medicinal chemistry.

Experimental postoperative adjuvant chemotherapy by UFT using primary tumor amputation model.

A. Fujioka, J. Uchida, H. Okabe, 2000, International journal of molecular medicine.