K. Romano

发表

Integrated genomics and chemical biology herald an era of sophisticated antibacterial discovery, from defining essential genes to target elucidation.

A. Clatworthy, D. Hung, Thulasi Warrier, 2022, Cell chemical biology.

The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors

Hong Cao, Christos J. Petropoulos, Celia A. Schiffer, 2012, PLoS pathogens.

Resistance from Afar: Distal Mutation V36M Allosterically Modulates the Active Site to Accentuate Drug Resistance in HCV NS3/4A Protease

C. Schiffer, C. Petropoulos, Ayşegül Özen, 2018, bioRxiv.

Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance.

C. Schiffer, C. Petropoulos, Cihan Aydın, 2013, ACS chemical biology.

Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding

C. Schiffer, W. Royer, Akbar Ali, 2010, Proceedings of the National Academy of Sciences.

Targeting LPS biosynthesis and transport in gram-negative bacteria in the era of multi-drug resistance

D. Hung, K. Romano, 2022, Biochimica et biophysica acta. Molecular cell research.

Mechanisms of Substrate Recognition by HCV NS3/4A Protease Provide Insights Into Drug Resistance: A Dissertation

K. Romano, 2011 .

Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa

Bradley E. Poulsen, D. Hung, B. Pentelute, 2019, Antimicrobial Agents and Chemotherapy.

Mutations in pmrB confer cross-resistance to the LptD inhibitor POL7080 and colistin in Pseudomonas aeruginosa

Bradley E. Poulsen, D. Hung, B. Pentelute, 2019, bioRxiv.

Whole-organism phenotypic screening for anti-infectives promoting host health

A. Clatworthy, D. Hung, K. Romano, 2018, Nature Chemical Biology.

Molecular Mechanisms of Viral and Host Cell Substrate Recognition by Hepatitis C Virus NS3/4A Protease

C. Schiffer, F. Massi, Laura M Deveau, 2011, Journal of Virology.

Molecular mechanisms of viral and host-cell substrate recognition by HCV NS3/4A protease

C. Schiffer, F. Massi, Laura M Deveau, 2011 .

Mechanism of Substrate Recognition by Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variants Revealed by a Novel Structural Intermediate

Celia A. Schiffer, C. Schiffer, E. Nalivaika, 2006, Journal of Virology.

DNA interstrand cross-linking by epichlorohydrin.

K. Romano, J. Millard, A. Newman, 2007, Chemical research in toxicology.

Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance.

C. Schiffer, C. Petropoulos, Wei Huang, 2013, ACS chemical biology.