C. Koolmeister

发表

Variation in germ line mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission

T. Wai, P. Chinnery, D. Samuels, 2012, Nature Genetics.

A role for BCL2L13 and autophagy in germline purifying selection of mtDNA

Lyuba V. Bozhilova, P. Chinnery, N. Larsson, 2022, bioRxiv.

FBXL4 deficiency increases mitochondrial removal by autophagy

Robert W. Taylor, I. Atanassov, N. Larsson, 2020, EMBO molecular medicine.

POLRMT does not transcribe nuclear genes

M. Falkenberg, Dusanka Milenkovic, C. Kukat, 2014, Nature.

High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo

I. Atanassov, N. Larsson, Chan Bae Park, 2021, Life Science Alliance.

TEFM regulates both transcription elongation and RNA processing in mitochondria

Stefan J. Siira, C. Gustafsson, Dusanka Milenkovic, 2019, EMBO reports.

Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response

M. Ringnér, O. Shupliakov, T. Perlmann, 2021, PLoS genetics.

Antigen receptor stimulation drives selection against pathogenic mtDNA variants that dysregulate lymphocyte responses

M. Pekalski, R. Holmdahl, D. Sheward, 2021, medRxiv.

Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse

A. Pajak, N. Larsson, R. Wibom, 2019, Science Advances.

Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion

Stefan J. Siira, C. La Morgia, M. Falkenberg, 2022, Nucleic acids research.

Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos

Sushma Sharma, A. Chabes, N. Larsson, 2020, Nature Metabolism.

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

C. Gustafsson, L. M. Wilhelmsson, N. Larsson, 2014, Nucleic acids research.

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

Stefan J. Siira, C. Gustafsson, M. Falkenberg, 2019, Molecular cell.

Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations

Yong Liu, L. Bäckdahl, M. Pekalski, 2023, JCI insight.

Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity

J. Zierath, A. Krook, R. Wibom, 2024, Nature metabolism.

Antigen receptor stimulation drives selection against pathogenic mtDNA 1 variants that dysregulate lymphocyte responses 2 the 4 development of adaptive immune responses

Yong Liu, L. Bäckdahl, M. Pekalski, 2021 .