J. Come

发表

2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2.

F. Salituro, S. Pazhanisamy, L. Swenson, 2009, Bioorganic & medicinal chemistry letters.

Convenient synthesis of N-(4-(2-aminopyridin-4-yl)thiazol-2-yl)-2-phenylacetamides

Jeremy Green, U. Bandarage, J. Come, 2006 .

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors.

G. Bemis, V. Savić, C. Moody, 2009, Bioorganic & medicinal chemistry letters.

Discovery of a Novel Series of Potent and Selective Alkynylthiazole-Derived PI3Kγ Inhibitors.

S. Mahajan, A. Aronov, M. Jacobs, 2020, ACS medicinal chemistry letters.

Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γ.

J. Griffith, Tiansheng Wang, V. Damagnez, 2015, Journal of medicinal chemistry.

Discovery and Optimization of Pyrazole Amides as Inhibitors of ELOVL1.

Kevin J. Gagnon, F. Maltais, P. Charifson, 2021, Journal of medicinal chemistry.

Synthesis of eight-membered carbocycles via intramolecular [6.pi. + 2.pi.] photocycloaddition of alkenyl tropones

K. S. Feldman, A. Freyer, J. Come, 1986 .

Small-molecule immunostimulants. Synthesis and activity of 7,8-disubstituted guanosines and structurally related compounds.

D. Klaubert, A. Reitz, S. Bell, 1994, Journal of medicinal chemistry.

Synthesis of the barbaralone nucleus via photocyclization of an alkynyl tropone

Bradley D. Smith, K. S. Feldman, G. Fegley, 1987 .

ROCK Inhibitors 4: Structure-Activity Relationship Studies of 7-Azaindole-Based Rho Kinase (ROCK) Inhibitors.

Jeremy Green, U. Bandarage, Huai Gao, 2020, Bioorganic & medicinal chemistry letters.

ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors.

M. Jacobs, Jeremy Green, U. Bandarage, 2018, Bioorganic & medicinal chemistry letters.

A convenient synthesis of 7-allyl-8-substituted guanosines

Robert H. Chen, J. Come, L. Burr, 1991 .

Mechanistic and preparative studies of the intramolecular photocyclization of methylated 2-(4-pentenyl)tropones

K. S. Feldman, D. Rotella, Ming‐Jung Wu, 1989 .

Synthesis of eight-membered carbocycles via intramolecular [6.pi. + 2.pi.] photocycloaddition of alkenyl tropones

K. S. Feldman, A. Freyer, J. Come, 1986 .

Guanosine Derivatives as Immunostimulants. Discovery of Loxoribine

Robert H. Chen, D. Klaubert, A. Reitz, 1994 .

Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).

J. Griffith, V. Damagnez, S. Mahajan, 2018, Journal of medicinal chemistry.

Cell-free formation of protease-resistant prion protein

P. Lansbury, G. J. Raymond, B. Chesebro, 1994, Nature.

Importance of seeding

P. Lansbury, J. Come, Paul E. FRASERt, 2005 .

A kinetic model for amyloid formation in the prion diseases: importance of seeding.

P E Fraser, P. Lansbury, P. Fraser, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis of Novel 7‐Allyl‐8‐Substituted Guanosines

Robert H. Chen, D. Klaubert, J. Come, 1991 .

Predisposition of prion protein homozygotes to Creutzfeldt-Jakob disease can be explained by a nucleation-dependent polymerization mechanism

P. Lansbury, J. Come, 1994 .

The Formation of Scrapie-Associated Prion Protein In Vitro

P. Lansbury, G. J. Raymond, B. Chesebro, 1996 .