Wolfgang Schmidt

Discovery of a novel class of inhaled dual pharmacology muscarinic antagonist and β2 agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD).

B. Riccardi, A. Rizzi, N. Cesari, 2021, Bioorganic & medicinal chemistry letters.

Discovery of Clinical Candidate CHF-6366: A Novel Super-soft Dual Pharmacology Muscarinic Antagonist and β2 Agonist (MABA) for the Inhaled Treatment of Respiratory Diseases.

S. Catinella, L. Venturi, P. Puccini, 2022, Journal of medicinal chemistry.

Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5.

H. Hemmerle, A. Brüggemann, B. Pirard, 2003, Journal of medicinal chemistry.

Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis.

V. Birault, Joelle Le, G. Dixon, 2012, Bioorganic & medicinal chemistry letters.