David J. Farr

发表

The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist.

J. Fozard, B. Faller, D. Wyss, 2010, Journal of medicinal chemistry.

In Vitro and in Vivo Pharmacological Characterization of 5-[ ( R )-2-( 5 , 6-Diethyl-indan-2-ylamino )-1-hydroxyethyl ]-8-hydroxy-1 H-quinolin-2one ( Indacaterol ) , a Novel Inhaled 2 Adrenoceptor Agonist with a 24h Duration of Action

J. Fozard, C. Battram, B. Cuenoud, 2006 .

Synthesis and biological properties of novel glucocorticoid androstene C-17 furoate esters.

J. Fozard, Deborah Hynx, Keith Butler, 2004, Bioorganic & medicinal chemistry.

The discovery of orally available thrombin inhibitors: studies towards the optimisation of CGH1668.

D. Janus, K. Menear, David J. Farr, 1998, Bioorganic & medicinal chemistry letters.

Studies towards the identification of potent, selective and bioavailable thrombin inhibitors.

D. Janus, K. Menear, D. Bentley, 1999, Bioorganic & medicinal chemistry letters.

Potent and selective xanthine-based inhibitors of phosphodiesterase 5.

M. Zurini, R. Naef, S. Watson, 2007, Bioorganic & medicinal chemistry letters.

The discovery of orally available thrombin inhibitors: optimisation of the P1 pharmacophore.

B. Wathey, D. Janus, K. Menear, 1999, Bioorganic & medicinal chemistry letters.

An investigation into the structure-activity relationships associated with the systematic modification of the β(2)-adrenoceptor agonist indacaterol.

J. Fozard, B. Cuenoud, S. Charlton, 2012, Bioorganic & medicinal chemistry letters.

In Vitro and in Vivo Pharmacological Characterization of 5-[(R)-2-(5,6-Diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-one (Indacaterol), a Novel Inhaled β2 Adrenoceptor Agonist with a 24-h Duration of Action

J. Fozard, C. Battram, B. Cuenoud, 2006, Journal of Pharmacology and Experimental Therapeutics.

The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist.

J. Fozard, S. Charlton, M. Gosling, 2014, Bioorganic & medicinal chemistry letters.