Yang Hong

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Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition

Y. Lai, J. Gan, Lifei Wang, 2020, Drug Metabolism and Disposition.

Transporter Studies with the 3-O-Sulfate Conjugate of 17α-Ethinylestradiol: Assessment of Human Kidney Drug Transporters

A. D. Rodrigues, Yong-Hae Han, Cliff Chen, 2010, Drug Metabolism and Disposition.

Transporter Studies with the 3-O-Sulfate Conjugate of 17α-Ethinylestradiol: Assessment of Human Liver Drug Transporters

A. D. Rodrigues, Yong-Hae Han, Cliff Chen, 2010, Drug Metabolism and Disposition.

Tissue distribution and tumor uptake of folate receptor–targeted epothilone folate conjugate, BMS-753493, in CD2F1 mice after systemic administration

W. Humphreys, F. Lee, J. Gan, 2016, Acta pharmaceutica Sinica. B.

Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode.

David S. Nirschl, Kimberly A. Foster, David S Nirschl, 2017, Journal of medicinal chemistry.

Characterization of a novel and selective CB1 antagonist as a radioligand for receptor occupancy studies.

K. Behnia, N. Murugesan, Z. Gu, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and characterization of tritium labeled N-((R)-1-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methyl-1-oxobutan-2-yl)-3-sulfamoylbenzamide.

J. Hynes, S. Bonacorsi, Balu N Balasubramanian, 2015, Journal of labelled compounds & radiopharmaceuticals.

Inhibition of in vivo [(3)H]MK-801 binding by NMDA receptor open channel blockers and GluN2B antagonists in rats and mice.

R. Pieschl, L. Bristow, A. Fernandes, 2015, European journal of pharmacology.

Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism.

A. D. Rodrigues, Jinping Gan, Yuan Tian, 2010, British journal of clinical pharmacology.

Changes to the HIV Long Terminal Repeat and to HIV Integrase Differentially Impact HIV Integrase Assembly, Activity, and the Binding of Strand Transfer Inhibitors*

D. Langley, M. Krystal, M. A. Walker, 2007, Journal of Biological Chemistry.

Biochemical and behavioral effects of PDE10A inhibitors: Relationship to target site occupancy

M. Seager, J. Macor, S. Gerritz, 2016, Neuropharmacology.

Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.

G. Shankar, J. Macor, C. Albright, 2022, Journal of medicinal chemistry.

Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.

Alan G. E. Wilson, G. Shankar, J. Macor, 2022, Journal of medicinal chemistry.

Preclinical metabolism and disposition of an orally bioavailable macrocyclic FXIa inhibitor

Y. Shu, W. R. Ewing, J. Luettgen, 2021, Xenobiotica; the fate of foreign compounds in biological systems.

Synthesis of [1,2‐3H]ethylamine hydrochloride and [3H]‐labeled apadenoson for a human ADME study

W. Humphreys, P. Crane, Donglu Zhang, 2008 .

Synthesis of Tritium Labeled 30 KDa PEG and Conjugation to form [3 H]Pegbelfermin.

S. Bonacorsi, J. Easter, R. Burrell, 2021, Journal of labelled compounds & radiopharmaceuticals.

[3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement

J. Macor, C. Albright, R. Pieschl, 2017, Neuropharmacology.

Synthesis of [3α-(3) H] 17α-hydroxy pregnenolone and [3α-(3) H] pregnenolone.

A. Balog, S. Bonacorsi, Sharon X Gong, 2014, Journal of labelled compounds & radiopharmaceuticals.