Akihiro Kikuchi

发表

Metformin Suppresses Expression of the Selenoprotein P gene via an AMPK-FoxO3a Pathway in H4IIEC3 Hepatocytes

H. Iwama, Hiroaki Takayama, H. Misu, 2013 .

Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples

S. Kaneko, Yoshiyuki Suzuki, H. Misu, 2018, PloS one.

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

M. Honda, S. Kaneko, Hiroaki Takayama, 2017, Nature Medicine.

LECT2 Functions as a Hepatokine That Links Obesity to Skeletal Muscle Insulin Resistance

S. Kaneko, Hong Tang, Hiroaki Takayama, 2014, Diabetes.

Rapid response of the steatosis-sensing hepatokine LECT2 during diet-induced weight cycling in mice.

S. Kaneko, Hiroaki Takayama, H. Misu, 2016, Biochemical and biophysical research communications.

The clinical course and potential underlying mechanisms of everolimus-induced hyperglycemia.

T. Takamura, K. Tokuyama, Takeo Tanaka, 2019, Endocrine journal.

LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH

S. Kaneko, Yasuhiko Yamamoto, Hiroaki Takayama, 2021, Scientific reports.

p62‐mediated autophagy affects nutrition‐dependent insulin receptor substrate 1 dynamics in 3T3‐L1 preadipocytes

S. Kaneko, H. Misu, T. Takamura, 2018, Journal of diabetes investigation.

Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

S. Kaneko, Miyuki Yamamoto, Keiji Tanaka, 2013, Diabetes.

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

M. Honda, Hiroaki Takayama, H. Misu, 2017, Nature Medicine.

Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes*

S. Kaneko, H. Iwama, K. Murao, 2013, The Journal of Biological Chemistry.

Metformin Suppresses Expression of the Selenoprotein P gene via an AMPK-FoxO3a Pathway in H4IIEC3 Hepatocytes

S. Kaneko, H. Iwama, K. Murao, 2013 .

Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in mice

Hiroaki Takayama, H. Misu, K. Chikamoto, 2020, Scientific Reports.

Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans.

S. Kaneko, Hiroaki Takayama, H. Misu, 2019, Biological & pharmaceutical bulletin.

Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes

S. Kaneko, H. Iwama, K. Murao, 2017, The Journal of Biological Chemistry.

LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH

Hiroaki Takayama, T. Takamura, S. Yamagoe, 2021, Scientific Reports.

Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes

Hiroaki Takayama, T. Takamura, Kiyo-aki Ishii, 2022, The Journal of Pharmacology and Experimental Therapeutics.

Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme USP14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes.

Hiroaki Takayama, Kiyo-aki Ishii, Akihiro Kikuchi, 2022 .

Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes*

S. Kaneko, H. Iwama, K. Murao, 2013, The Journal of Biological Chemistry.