K. Köck

发表

Role of Multidrug Resistance–Associated Protein 4 in the Basolateral Efflux of Hepatically Derived Enalaprilat

K. Brouwer, Arlene S. Bridges, B. Ferslew, 2014, Drug Metabolism and Disposition.

Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation

K. Brouwer, W. Yue, J. Powell, 2014, Drug Metabolism and Disposition.

DMD048272 958..965

K. Brouwer, N. Oberlies, R. Hawke, 2013 .

Application Delivery System for the Prevention of In-Stent Restenosis in Coronary Biodegradable Sirolimus-loaded Poly ( lactide ) Nanoparticles as Drug

W., W. Weitschies, Henning, 2010 .

DMD057554 1567..1574

K. Brouwer, Arlene S. Bridges, B. Ferslew, 2014 .

Special Section on Transporters in Toxicity and Disease Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4

K. Brouwer, P. Swaan, T. Urban, 2014 .

DMD056945 1964..1970

K. Brouwer, W. Yue, J. Powell, 2014 .

Population pharmacokinetics of brodalumab in healthy adults and adults with psoriasis from single and multiple dose studies

D. Salinger, C. Endres, M. Gibbs, 2014, Journal of clinical pharmacology.

Prediction of clinical pharmacokinetics of AMG 181, a human anti-α4β7 monoclonal antibody for treating inflammatory bowel diseases

D. Salinger, H. Hsu, W. Rees, 2014, Pharmacology research & perspectives.

An updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters.

A. Tropsha, Alexander Sedykh, K. Brouwer, 2013, Journal of pharmaceutical sciences.

Expression of ABCC-Type Nucleotide Exporters in Blasts of Adult Acute Myeloid Leukemia: Relation to Long-term Survival

H. Kroemer, V. Gandhi, Zhe-Sheng Chen, 2009, Clinical Cancer Research.

Cellular Export of Drugs and Signaling Molecules by the ATP-binding Cassette Transporters MRP4 (ABCC4) and MRP5 (ABCC5)

H. Kroemer, H. E. Meyer zu Schwabedissen, M. Grube, 2005, Drug metabolism reviews.

Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4

K. Brouwer, P. Swaan, T. Urban, 2014, Drug Metabolism and Disposition.

Expression of Adenosine Triphosphate-Binding Cassette (ABC) Drug Transporters in Peripheral Blood Cells

H. Kroemer, L. Oevermann, W. Siegmund, 2007, Clinical pharmacokinetics.

Organic Anion Transporting Polypeptide 2B1 and Breast Cancer Resistance Protein Interact in the Transepithelial Transport of Steroid Sulfates in Human Placenta

H. Kroemer, C. Fusch, H. E. Meyer zu Schwabedissen, 2007, Drug Metabolism and Disposition.

Organic anion transporting polypeptide 2B1 is a high‐affinity transporter for atorvastatin and is expressed in the human heart

Michael Böhm, Markus Grube, Werner Siegmund, 2006, Clinical pharmacology and therapeutics.

A Perspective on Efflux Transport Proteins in the Liver

K. Brouwer, K. Köck, K. R. Brouwer, 2012, Clinical pharmacology and therapeutics.

Hematopoietic stem cell differentiation affects expression and function of MRP4 (ABCC4), a transport protein for signaling molecules and drugs

H. Kroemer, J. Niessen, A. Greinacher, 2009, International journal of cancer.

Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors

Peter W Swaan, Kim L R Brouwer, K. Brouwer, 2015, Drug Metabolism and Disposition.

Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides

K. Brouwer, Ying Xie, N. Oberlies, 2013, Drug Metabolism and Disposition.

Drug Transport in the Liver

K. Brouwer, K. Köck, B. Ferslew, 2014 .

Drug Efflux Transporter Multidrug Resistance-Associated Protein 5 Affects Sensitivity of Pancreatic Cancer Cell Lines to the Nucleoside Anticancer Drug 5-Fluorouracil

D. Rosskopf, J. Mayerle, M. Lerch, 2011, Drug Metabolism and Disposition.

Modeling the pharmacokinetic‐pharmacodynamic relationship of the monoclonal anti‐macaque‐IL‐15 antibody Hu714MuXHu in cynomolgus monkeys

L. Wienkers, H. Lebrec, M. Horner, 2015, Pharmacology research & perspectives.

Preclinical development of AMG 139, a human antibody specifically targeting IL‐23

J. Gow, Y. Sun, Y. Zhang, 2015, British journal of pharmacology.

Clinical pharmacology of AMG 181, a gut-specific human anti-α4β7 monoclonal antibody, for treating inflammatory bowel diseases.

J. Gow, J. Andrews, G. Radford-Smith, 2014, British journal of clinical pharmacology.

Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy.

U. Völker, W. Hoffmann, S. Felix, 2011, The American journal of pathology.

Modification of OATP2B1-Mediated Transport by Steroid Hormones

H. Kroemer, M. Grube, G. Jedlitschky, 2006, Molecular Pharmacology.

Analysis of Hepatic Transport Proteins

K. Brouwer, Kyunghee Yang, K. Köck, 2013 .

Steroid hormones specifically modify the activity of organic anion transporting polypeptides.

H. Kroemer, W. Siegmund, M. Keiser, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Rapid Modulation of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1, SLCO2B1) Function by Protein Kinase C-mediated Internalization*

M. Fraunholz, U. Völker, H. Kroemer, 2010, The Journal of Biological Chemistry.

Species Differences in Hepatobiliary Disposition of Taurocholic Acid in Human and Rat Sandwich-Cultured Hepatocytes: Implications for Drug-Induced Liver Injury

K. Brouwer, Kyunghee Yang, K. Köck, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Biodegradable Sirolimus-loaded Poly(lactide) Nanoparticles as Drug Delivery System for the Prevention of In-Stent Restenosis in Coronary Stent Application

Katrin Sternberg, Klaus-Peter Schmitz, Werner Weitschies, 2011, Journal of biomaterials applications.

Prioritizing Pharmacokinetic Drug Interaction Precipitants in Natural Products: Application to OATP Inhibitors in Grapefruit Juice

M. Paine, K. Köck, Emily J Johnson, 2017, Biopharmaceutics & drug disposition.

Novel Mechanism of Impaired Function of Organic Anion-Transporting Polypeptide 1B3 in Human Hepatocytes: Post-Translational Regulation of OATP1B3 by Protein Kinase C Activation

K. Brouwer, W. Yue, J. Powell, 2014, Drug Metabolism and Disposition.

Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4

K. Brouwer, P. Swaan, T. Urban, 2014, Drug Metabolism and Disposition.

Steroid hormones specifically modify the activity of organic anion transporting polypeptides.

H. Kroemer, W. Siegmund, M. Keiser, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.