J. Wagner

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Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.

C. Langefeld, G. Hawkins, T. Howard, 2009, Comparative medicine.

A study of caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): a potential model for aging research.

W. Cefalu, Trefor Owen Morgan, R. Bechtold, 1997, The journals of gerontology. Series A, Biological sciences and medical sciences.

Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey

J. Cline, A. Frankel, P. Hall, 2005, Cancer Immunology, Immunotherapy.

Clinicopathologic Characterization of Naturally Occurring Diabetes Mellitus in Vervet Monkeys

G. Hawkins, T. Howard, L. Fairbanks, 2010 .

A comparison of tibolone and conjugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys.

M. Anthony, T. Clarkson, J. Wagner, 2001, The Journal of clinical endocrinology and metabolism.

The effects of hormone replacement therapy on carbohydrate metabolism and cardiovascular risk factors in surgically postmenopausal cynomolgus monkeys.

W. Cefalu, M. Anthony, T. Clarkson, 1996, Metabolism: clinical and experimental.

Effects of 17 alpha-dihydroequilenin sulfate on atherosclerotic male and female rhesus monkeys.

J. Cline, T. Clarkson, S. Washburn, 1996, American journal of obstetrics and gynecology.

Consumption of soy protein reduces cholesterol absorption compared to casein protein alone or supplemented with an isoflavone extract or conjugated equine estrogen in ovariectomized cynomolgus monkeys.

M. Wilson, L. Rudel, K. Greaves, 2000, The Journal of nutrition.

The applicability of hormonal effects on atherosclerosis in animals to heart disease in postmenopausal women.

T. Clarkson, J. Wagner, 2005, Seminars in reproductive medicine.

Addition of medroxyprogesterone acetate to conjugated equine estrogens results in insulin resistance in adipose tissue.

M. Anthony, K. Kavanagh, M. Shadoan, 2007, Metabolism: clinical and experimental.

Effects of soy vs. casein protein on body weight and glycemic control in female monkeys and their offspring

J. Cline, J. Kaplan, A. Franke, 2009, American journal of primatology.

Streptozotocin-induced diabetes mellitus in cynomolgus monkeys: changes in carbohydrate metabolism, skin glycation, and pancreatic islets.

W. Cefalu, K. Litwak, J. Wagner, 1998, Laboratory animal science.

Epigenetic Changes with Dietary Soy in Cynomolgus Monkeys

G. Hawkins, M. Medvedovic, S. Ho, 2011, PloS one.

Caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): metabolic, physiologic, and atherosclerotic measures from a 4-year intervention trial.

W. Cefalu, T. Morgan, Zhong Q. Wang, 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.

A Selective Peroxisome Proliferator-Activated Receptor α Agonist, CP-900691, Improves Plasma Lipids, Lipoproteins, and Glycemic Control in Diabetic Monkeys

O. Francone, L. Royer, B. Auerbach, 2010, Journal of Pharmacology and Experimental Therapeutics.

Phytoestrogen and intact soy protein consumption differ in their effects on plasma lipids and lipoproteins.

J. Parks, L. Zhang, K. Greaves, 1999, Journal of medicinal food.

In vitro lipid peroxidation of LDL from postmenopausal cynomolgus macaques treated with female hormones.

M. Adams, D. Schwenke, J. Wagner, 1999, Journal of lipid research.

A Selective Cannabinoid-1 Receptor Antagonist, PF-95453, Reduces Body Weight and Body Fat to a Greater Extent than Pair-Fed Controls in Obese Monkeys

B. Auerbach, K. Kavanagh, H. J. Harwood, 2010, Journal of Pharmacology and Experimental Therapeutics.

Effects of hormone therapy on insulin signaling proteins in skeletal muscle of cynomolgus monkeys

M. Shadoan, Li Zhang, J. Wagner, 2004, Steroids.

Diabetes mellitus and islet amyloidosis in cynomolgus monkeys.

W. Cefalu, M. Anthony, T. O’Brien, 1996, Laboratory animal science.

Glycation of plasma low density lipoproteins increases interaction with arterial proteoglycans.

W. Cefalu, K. Litwak, L. Rudel, 1999, Diabetes research and clinical practice.

Islet Amyloid and Islet Amyloid Polypeptide in Cynomolgus Macaques (Macaca fascicularis): An Animal Model of Human Non-insulin-dependent Diabetes Mellitus

W. Cefalu, K. Litwak, P. Butler, 1996, Veterinary pathology.

Increased glycation of plasma lipoproteins in diabetic cynomolgus monkeys.

W. Cefalu, K. Litwak, L. Zhang, 1996, Laboratory animal science.

Gestational diabetes mellitus in a cynomolgus monkey with group A streptococcal metritis and hemolytic uremic syndrome.

B. Bullock, S. Washburn, M. Jayo, 1992, Journal of medical primatology.

Role of glycated proteins in detecting and monitoring diabetes in cynomolgus monkeys.

W. Cefalu, A. Bell-Farrow, J. Wagner, 1993, Laboratory animal science.

Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum

R. Subramanian, Zhili Song, C. Pachuk, 2011, Journal of Lipid Research.

Restoring HSP70 deficiencies improves glucose tolerance in diabetic monkeys.

D. Flynn, K. Kavanagh, Li Zhang, 2011, American journal of physiology. Endocrinology and metabolism.

Effects of estrogens, progestins, and androgens on atherosclerosis and other metabolic parameters

J. Wagner, 1999 .

Effects of tibolone and conjugated equine estrogens with or without medroxyprogesterone acetate on body composition and fasting carbohydrate measures in surgically postmenopausal monkeys.

S. E. Rankin, M. Anthony, T. Clarkson, 2003, Metabolism: clinical and experimental.

Sex steroids increase cholesterol 7α-hydroxylase mRNA in nonhuman primates

M. Adams, M. Sorci-Thomas, P. Colvin, 1998 .

Oral contraceptives decrease hepatic cholesterol independent of the LDL receptor in nonhuman primates.

M. Sorci-Thomas, P. Colvin, M. Heuser, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

Toxicology and Pharmacokinetics of DT388IL3, a Fusion Toxin Consisting of a Truncated Diphtheria Toxin (DT388) Linked to Human Interleukin 3 (IL3), in Cynomolgus Monkeys

J. Cline, A. Frankel, P. Hall, 2004, Leukemia & lymphoma.

Ongoing b -Cell Turnover in Adult Nonhuman Primates Is Not Adaptively Increased in Streptozotocin-Induced Diabetes

C. Cobelli, G. Toffolo, P. Butler, 2011 .

Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys

C. Cobelli, G. Toffolo, P. Butler, 2009, Diabetologia.

Title Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys Permalink

C. Cobelli, G. Toffolo, P. Butler, 2009 .

Neonatal and fetal exposure to trans-fatty acids retards early growth and adiposity while adversely affecting glucose in mice.

J. Carr, L. Rudel, K. Kavanagh, 2010, Nutrition research.

Effects of soy protein and isoflavones on insulin resistance and adiponectin in male monkeys.

M. Adams, J. Kaplan, Haiying Chen, 2008, Metabolism: clinical and experimental.

Soy protein reduces the arterial low-density lipoprotein (LDL) concentration and delivery of LDL cholesterol to the arteries of diabetic and nondiabetic male cynomolgus monkeys.

L. Zhang, K. Greaves, D. Schwenke, 2000, Metabolism: clinical and experimental.

Dual radiotracer analysis of cholinergic neuronal changes in prediabetic mouse pancreas.

H. Gage, J. Callés-Escandon, P. Garg, 2009, Diabetes technology & therapeutics.

Ongoing β-Cell Turnover in Adult Nonhuman Primates Is Not Adaptively Increased in Streptozotocin-Induced Diabetes

C. Cobelli, G. Toffolo, P. Butler, 2011, Diabetes.

Methyltestosterone Does Not Diminish the Beneficial Effects of Estrogen Replacement Therapy on Coronary Artery Reactivity in Cynomolgus Monkeys

M. Adams, E. Honoré, K. Williams, 1996 .

Intact dietary soy protein, but not adding an isoflavone-rich soy extract to casein, improves plasma lipids in ovariectomized cynomolgus monkeys.

J. Parks, J. D. Wagner, K. Greaves, 1999, The Journal of nutrition.

Dietary soy protein and estrogen replacement therapy improve cardiovascular risk factors and decrease aortic cholesteryl ester content in ovariectomized cynomolgus monkeys.

W. Cefalu, J. D. Wagner, M. Anthony, 1997, Metabolism: clinical and experimental.

Genomic Diversity and Interspecies Host Infection of Α12 Macaca Fascicularis Papillomaviruses (mfpvs)

R. DeSalle, R. Burk, Zigui Chen, 2022 .

Condylomatous Genital Lesions in Cynomolgus Macaques from Mauritius

R. Burk, Ariana Harari, Zigui Chen, 2013, Toxicologic pathology.

Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance.

J. Cline, J. Ibdah, P. Rinaldo, 2005, Gastroenterology.

Estrogen and progesterone replacement therapy reduces low density lipoprotein accumulation in the coronary arteries of surgically postmenopausal cynomolgus monkeys.

C. Shively, J. D. Wagner, T. Clarkson, 1991, The Journal of clinical investigation.

Characterization and validation of a streptozotocin-induced diabetes model in the vervet monkey.

D. Flynn, K. Kavanagh, Li Zhang, 2011, Journal of pharmacological and toxicological methods.

Aging and atherosclerosis in human and nonhuman primates

W. Cefalu, J. Wagner, 1997, AGE.

Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Insulin Sensitivity and Cardiovascular Risk Factors in Ovariectomized Monkeys with Estradiol Alone or Combined with Nomegestrol Acetate*

W. Cefalu, J. D. Wagner, L. Zhang, 2022 .

Diverse Non-genetic, Allele-Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain

C. Gregg, J. D. Wagner, Wei-Chao Huang, 2017, Neuron.

Fluid compartmental shifts with efficacious pioglitazone therapy in overweight monkeys: implications for peroxisome proliferator-activated receptor-gamma agonist use in prediabetes.

Mandy L Berquist, K. Brown, K. Kavanagh, 2010, Metabolism: clinical and experimental.

Diabetes and Obesity Research using Nonhuman Primates

H. J. Harwood, J. Cann, Li Zhang, 2012 .

Life stage differences in mammary gland gene expression profile in non-human primates

J. Cline, P. Stute, C. E. Wood, 2012, Breast Cancer Research and Treatment.

Effects of Estrogens and Progestins on Atherosclerosis in Primates

J. D. Wagner, T. Clarkson, M. Adams, 1992 .

Characterization and Heritability of Obesity and Associated Risk Factors in Vervet Monkeys

L. Fairbanks, L. Rudel, J. Bailey, 2007, Obesity.

Effects of 17α-dihydroequilenin sulfate on atherosclerotic male and female rhesus monkeys

J. Cline, T. Clarkson, S. Washburn, 1996 .

Trans Fat Diet Induces Abdominal Obesity and Changes in Insulin Sensitivity in Monkeys

J. Sawyer, L. Rudel, K. Kavanagh, 2007, Obesity.

Medroxyprogesterone acetate antagonizes inhibitory effects of conjugated equine estrogens on coronary artery atherosclerosis.

M. Adams, T. Register, J. Williams, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Effects of hormone replacement modalities on low density lipoprotein composition and distribution in ovariectomized cynomolgus monkeys.

J. Parks, J. D. Wagner, M. Adams, 1996, Atherosclerosis.

Soy Protein With Isoflavones, but not an Isoflavone-Rich Supplement, Improves Arterial Low-Density Lipoprotein Metabolism and Atherogenesis

R. Blair, J. D. Wagner, M. Anthony, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Reproductive hormones and cardiovascular disease mechanism of action and clinical implications.

J. Kaplan, R. Burkman, J. Wagner, 2002, Obstetrics and gynecology clinics of North America.

Effects of Mammalian and Plant Estrogens on Lipoprotein Metabolism and Coronary Heart Disease

J. D. Wagner, K. Greaves, D. Schwenke, 2000 .

Nutrient Metabolism Consumption of Soy Protein Reduces Cholesterol Absorption Compared to Casein Protein Alone or Supplemented with an Isoflavone Extract or Conjugated Equine Estrogen in Ovariectomized Cynomolgus Monkeys 1

J. D. Wagner, L. Rudel, K. Greaves, 2000 .

Soy protein versus soy phytoestrogens in the prevention of diet-induced coronary artery atherosclerosis of male cynomolgus monkeys.

J. D. Wagner, M. Anthony, T. Clarkson, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Effects of Short-term Hormone Replacement Therapies on Low-Density Lipoprotein Metabolism in Cynomolgus Monkeys

J. D. Wagner, M. Adams, J. Bagdade, 1997 .

Esterified estrogens with and without methyltestosterone decrease arterial LDL metabolism in cynomolgus monkeys.

J. D. Wagner, L. Zhang, T. Clarkson, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys.

J. Parks, J. D. Wagner, M. Adams, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes

Sang Han Lee, E. Petkova, P. Mathews, 2016, The Journal of Neuroscience.

Single‐Nucleotide Polymorphisms in the TNF Gene Are Associated With Obesity‐Related Phenotypes in Vervet Monkeys

C. Langefeld, G. Hawkins, T. Howard, 2011, Obesity.

Effects of soy isoflavones and conjugated equine estrogens on inflammatory markers in atherosclerotic, ovariectomized monkeys.

R. Blair, J. D. Wagner, M. Anthony, 2005, The Journal of clinical endocrinology and metabolism.

The effects of hormonal replacement therapy on insulin sensitivity in surgically postmenopausal cynomolgus monkeys (Macaca fascicularis).

C. Cobelli, G. Toffolo, W. Cefalu, 1994, American journal of obstetrics and gynecology.

Estrogen Decreases Atherosclerosis in Part by Reducing Hepatic Acyl-CoA:Cholesterol Acyltransferase 2 (ACAT2) in Monkeys

J. D. Wagner, M. Adams, L. Rudel, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Oral contraceptive treatment decreases arterial low density lipoprotein degradation in female cynomolgus monkeys.

J. D. Wagner, T. Clarkson, M. Adams, 1993, Circulation research.

Nonhuman Primates and other Animal Models in Diabetes Research

H. J. Harwood, J. Wagner, Paul Listrani, 2012, Journal of diabetes science and technology.

High isoflavone soy diet increases insulin secretion without decreasing insulin sensitivity in premenopausal nonhuman primates.

J. D. Wagner, K. L. Jones, D. Flynn, 2008, Nutrition research.

Type 2 diabetes-an introduction to the development and use of animal models.

J. D. Wagner, J. Kaplan, J. Wagner, 2006, ILAR journal.

Effects of tibolone and conventional hormone replacement therapies on arterial and hepatic cholesterol accumulation and on circulating endothelin-1, vascular cell adhesion molecule-1, and E-selectin in surgically menopausal monkeys

J. D. Wagner, T. Clarkson, T. Register, 2002, Menopause.

Short-term hyperglycemia increases arterial superoxide production and iron dysregulation in atherosclerotic monkeys.

J. D. Wagner, P. Rowe, K. Kavanagh, 2011, Metabolism: clinical and experimental.

Modulation of Skeletal Muscle Insulin Signaling With Chronic Caloric Restriction in Cynomolgus Monkeys

W. Cefalu, Jianhua Qin, Yongmei Yu, 2009, Diabetes.

Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy.

J. D. Wagner, G. Hammond, T. Rabe, 2001, American journal of obstetrics and gynecology.

Effects of 17a-dihydroequilenin sulfate on and female rhesus monkeys atherosclerotic

J. Cline, T. Clarkson, S. Washburn, 1996 .

Tamoxifen inhibits arterial accumulation of LDL degradation products and progression of coronary artery atherosclerosis in monkeys.

J. D. Wagner, M. Adams, J. Williams, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Regional differences in arterial low density lipoprotein metabolism in surgically postmenopausal cynomolgus monkeys. Effects of estrogen and progesterone replacement therapy.

C. Shively, J. D. Wagner, T. Clarkson, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Accelerated cholesteryl ester transfer and altered lipoprotein composition in diabetic cynomolgus monkeys.

J. D. Wagner, T. B. Clarkson, J. Bagdade, 1995, Journal of lipid research.

Rationale for hormone replacement therapy in atherosclerosis prevention.

J. Wagner, 2000, The Journal of reproductive medicine.

Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date.

R. Weindruch, W. Cefalu, J. Terry, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Chronic hyperglycemia increases arterial low-density lipoprotein metabolism and atherosclerosis in cynomolgus monkeys.

W. Cefalu, J. D. Wagner, K. Litwak, 1998, Metabolism: clinical and experimental.

Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys

K. Kavanagh, Li Zhang, J. Wagner, 2009, Cell Stress and Chaperones.

Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys

W. Cefalu, J. D. Wagner, K. Litwak, 2004, Cardiovascular diabetology.

Soy Phytoestrogens: Research on Benefits and Risks

J. Cline, J. D. Wagner, M. Anthony, 2001, Clinical obstetrics and gynecology.

Naturally occurring menopause in cynomolgus monkeys: changes in hormone, lipid, and carbohydrate measures with hormonal status

J. D. Wagner, K. Kavanagh, J. Koudy Williams, 2005, Journal of medical primatology.

Hydrogen and Oxygen Isotope Ratios in Body Water and Hair: Modeling Isotope Dynamics in Nonhuman Primates

J. Ehleringer, C. Remien, J. Kaplan, 2012, American journal of primatology.

Rosiglitazone treatment improves insulin regulation and dyslipidemia in type 2 diabetic cynomolgus monkeys.

S. E. Rankin, R. Kauffman, Li Zhang, 2004, Metabolism: clinical and experimental.

Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys.

J. Cline, N. Kock, H. Ding, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Gluten-sensitive enteropathy in a cynomolgus monkey.

M. Adams, C. Jerome, J. Wagner, 1988, Laboratory animal science.

Naturally Occurring and Experimental Diabetes in Cynomolgus Monkeys: A Comparison of Carbohydrate and Lipid Metabolism and Islet Pathology

S. E. Rankin, W. Cefalu, J. Cline, 2001, Toxicologic pathology.

Caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): metabolic, physiologic, and atherosclerotic measures from a 4-year intervention trial.

W. Cefalu, T. Morgan, Zhong Q. Wang, 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.

Enhanced cholinergic response in pancreata of nonhuman primates with impaired glucose tolerance shown on [18F]fluorobenzyltrozamicol positron emission tomography.

H. Gage, J. Callés-Escandon, P. Garg, 2009, Diabetes technology & therapeutics.