Sudarshan Kapadnis

Neuropharmacokinetics of two investigational compounds in rats: divergent temporal profiles in the brain and cerebrospinal fluid.

Xing Chen, D. Flood, D. Welty, 2014, Biochemical pharmacology.

Design, Synthesis, and Evaluation of a Novel Series of Oxadiazine Gamma Secretase Modulators for Familial Alzheimer's Disease.

D. Burnett, Raksha A. Acharya, H. Patzke, 2017, Journal of medicinal chemistry.

Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis.

M. Mingueneau, J. Lyssikatos, T. Bohnert, 2021, Journal of medicinal chemistry.

Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator.

D. Burnett, Raksha A. Acharya, H. Patzke, 2021, Journal of medicinal chemistry.

Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease

D. Burnett, H. Patzke, Cuyue Tang, 2016, Alzheimer's Research & Therapy.

Optimization of dose and route of administration of the P‐glycoprotein inhibitor, valspodar (PSC‐833) and the P‐glycoprotein and breast cancer resistance protein dual‐inhibitor, elacridar (GF120918) as dual infusion in rats

Patrick E. Trapa, Alicia Pietrasiewicz, Sudarshan Kapadnis, 2021, Pharmacology research & perspectives.

Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease

D. Burnett, H. Patzke, Cuyue Tang, 2016, Alzheimer's Research & Therapy.

Prospective Validation of Machine Learning Algorithms for Absorption, Distribution, Metabolism, and Excretion Prediction: An Industrial Perspective

Patrick E. Trapa, Cheng Fang, Simone Sciabola, 2023, J. Chem. Inf. Model..