Melody Wen

Neuropharmacokinetics of two investigational compounds in rats: divergent temporal profiles in the brain and cerebrospinal fluid.

Xing Chen, D. Flood, D. Welty, 2014, Biochemical pharmacology.

Design, Synthesis, and Evaluation of a Novel Series of Oxadiazine Gamma Secretase Modulators for Familial Alzheimer's Disease.

D. Burnett, Raksha A. Acharya, H. Patzke, 2017, Journal of medicinal chemistry.

Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator.

D. Burnett, Raksha A. Acharya, H. Patzke, 2021, Journal of medicinal chemistry.

Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice

B. de Strooper, H. Zetterberg, L. Leventhal, 2012, Molecular Neurodegeneration.

Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice

B. de Strooper, H. Zetterberg, L. Leventhal, 2012, Molecular Neurodegeneration.