Kensuke Sakuma

Fasiglifam (TAK‐875) has dual potentiating mechanisms via Gαq‐GPR40/FFAR1 signaling branches on glucose‐dependent insulin secretion

K. Takeuchi, H. Komatsu, M. Maruyama, 2016, Pharmacology research & perspectives.

A Novel Antidiabetic Drug, Fasiglifam/TAK-875, Acts as an Ago-Allosteric Modulator of FFAR1

K. Takeuchi, H. Komatsu, Y. Habata, 2013, PloS one.

CDK8/19 inhibition plays an important role in pancreatic β-cell induction from human iPSCs

H. Ueno, B. Saito, Taro Toyoda, 2023, Stem Cell Research & Therapy.

Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC

H. Matsumoto, Shuhei Konagaya, Taro Toyoda, 2022, Scientific reports.

C. elegans AMPKs promote survival and arrest germline development during nutrient stress

A. Rougvie, H. Kajiho, T. Katada, 2012, Biology Open.

FTBMT, a Novel and Selective GPR52 Agonist, Demonstrates Antipsychotic-Like and Procognitive Effects in Rodents, Revealing a Potential Therapeutic Agent for Schizophrenia

Y. Shimizu, K. Nishiyama, H. Komatsu, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Temporal and Spatial Transcriptional Fingerprints by Antipsychotic or Propsychotic Drugs in Mouse Brain

H. Komatsu, M. Maruyama, Y. Habata, 2015, PloS one.

Anatomical Transcriptome of G Protein-Coupled Receptors Leads to the Identification of a Novel Therapeutic Candidate GPR52 for Psychiatric Disorders

T. Shinohara, H. Komatsu, M. Maruyama, 2014, PloS one.

Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y2 agonist, on cardiomyocytes in neonatal rats

Hideyuki Nakagawa, S. Ikeda, Tatsuo Oikawa, 2017, Scientific Reports.

Identification and removal of unexpected proliferative off-target cells emerging after iPSC-derived pancreatic islet cell implantation

Shuhei Konagaya, Taro Toyoda, T. Mochida, 2024, Proceedings of the National Academy of Sciences of the United States of America.