Xin‐hua Zhang

发表

HDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs

Mei Han, Bin Zheng, J. Wen, 2011, Cell Research.

miR-155 down-regulation protects the heart from hypoxic damage by activating fructose metabolism in cardiac fibroblasts

Hong Zhang, J. Wen, Tian-ying Zhai, 2021, Journal of advanced research.

Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission

Toru Suzuki, Bin Zheng, J. Wen, 2020, PLoS biology.

eIF5a reduction via decreased Klf5 leads to cell senescence by mitochondrial fission in VSMCs

Toru Suzuki, Bin Zheng, J. Wen, 2019, bioRxiv.

Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline‐induced pulmonary inflammation and vascular remodelling

Yun Wang, Huai-liang Wang, Ming Liu, 2011, Clinical and experimental pharmacology & physiology.

Synthetic retinoid Am80 inhibits interaction of KLF5 with RARα through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells

Mei Han, Bin Zheng, J. Wen, 2009, FEBS letters.

Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose.

Bin Zheng, J. Wen, Lihui Zhang, 2020, Journal of ethnopharmacology.

Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages.

Bin Zheng, J. Wen, Wen-Yan Jiang, 2016, American journal of translational research.

SUMOylation of KLF4 acts as a switch in transcriptional programs that control VSMC proliferation.

Guo-liang Zhang, Bin Zheng, J. Wen, 2016, Experimental cell research.

Exosome-Mediated miR-155 Transfer from Smooth Muscle Cells to Endothelial Cells Induces Endothelial Injury and Promotes Atherosclerosis.

Toru Suzuki, Hong Zhang, Bin Zheng, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration.

Man-Li Zhang, Bin Zheng, J. Wen, 2017, Biochimica et biophysica acta. Molecular basis of disease.

TMEM16A and Myocardin Form a Positive Feedback Loop That Is Disrupted by KLF5 During Ang II–Induced Vascular Remodeling

Xuan Zhang, Ruonan Zhang, M. He, 2015, Hypertension.

Synthetic retinoid Am 80 upregulates apelin expression by promoting interaction of RAR α with KLF 5 and Sp 1 in vascular smooth muscle cells

Bin Zheng, J. Wen, Yan Liu, 2013 .

Synthetic retinoid Am80 up-regulates apelin expression by promoting interaction of RARα with KLF5 and Sp1 in vascular smooth muscle cells.

Bin Zheng, J. Wen, Yan Liu, 2013, The Biochemical journal.

Krüppel-like Factor 4 Inhibits Proliferation by Platelet-derived Growth Factor Receptor β-mediated, Not by Retinoic Acid Receptor α-mediated, Phosphatidylinositol 3-Kinase and ERK Signaling in Vascular Smooth Muscle Cells*

Mei Han, M. Bernier, M. He, 2009, The Journal of Biological Chemistry.

Effects of dl-praeruptorin A on interleukin-6 level and Fas, bax, bcl-2 protein expression in ischemia-reperfusion myocardium.

Huai-liang Wang, Xiao-yang Liu, Xin‐hua Zhang, 2002, Acta pharmacologica Sinica.

Salvianolic acid B inhibits Ang II-induced VSMC proliferation in vitro and intimal hyperplasia in vivo by downregulating miR-146a expression.

Bin Zheng, J. Wen, Xin‐hua Zhang, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Novel insight into Y‐box binding protein 1 in the regulation of vascular smooth muscle cell proliferation through targeting GC box‐dependent genes

Bin Zheng, J. Wen, Yong-hui Li, 2013, FEBS letters.

All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells.

Mei Han, Bin Zheng, J. Wen, 2009, Biochemical and biophysical research communications.

Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.

Yun Wang, Huai-liang Wang, Xin‐hua Zhang, 2011, Canadian journal of physiology and pharmacology.

Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA-Rho kinase and Akt signalling pathways in rats.

Yang Bai, Yun Wang, Huai-liang Wang, 2012, Canadian journal of physiology and pharmacology.

Fluoxetine Attenuates Chronic Methamphetamine‐induced Pulmonary Arterial Remodelling: Possible Involvement of Serotonin Transporter and Serotonin 1B Receptor

Yang Bai, Yun Wang, Huai-liang Wang, 2013, Basic & clinical pharmacology & toxicology.

Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.

Ruonan Zhang, Bin Zheng, J. Wen, 2014, American journal of physiology. Heart and circulatory physiology.

Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension.

Huai-liang Wang, Xin‐hua Zhang, Tian-hui Chang, 2002, Acta pharmacologica Sinica.

Tetrandrine prevents monocrotaline‐induced pulmonary hypertension in rats

Huai-liang Wang, Huixia Jin, Yang Hong, 1996 .

Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats

Huai-liang Wang, Dan-dan Han, Xin‐hua Zhang, 2011, Acta Pharmacologica Sinica.

FLUOXETINE PROTECTS AGAINST MONOCROTALINE‐INDUCED PULMONARY ARTERIAL HYPERTENSION: POTENTIAL ROLES OF INDUCTION OF APOPTOSIS AND UPREGULATION OF Kv1.5 CHANNELS IN RATS

Huai-liang Wang, F. Zhai, Xin‐hua Zhang, 2009, Clinical and experimental pharmacology & physiology.

TGF-&bgr;1 Downregulates AT1 Receptor Expression via PKC-&dgr;-Mediated Sp1 Dissociation From KLF4 and Smad-Mediated PPAR-&ggr; Association With KLF4

Bin Zheng, J. Wen, Xin‐hua Zhang, 2012, Arteriosclerosis, thrombosis, and vascular biology.

KLF4 mediates the link between TGF‐β1‐induced gene transcription and H3 acetylation in vascular smooth muscle cells

M. He, Bin Zheng, J. Wen, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PPAR-γ agonist stabilizes KLF4 protein via activating Akt signaling and reducing KLF4 ubiquitination.

M. He, Bin Zheng, J. Wen, 2014, Biochemical and biophysical research communications.

Atorvastatin but not elocalcitol increases sildenafil responsiveness in Spontaneously Hypertensive 1 Rats by regulating the RhoA / ROCK pathway 2 Running title : Atorvastatin and sildenafil in SHR 3 1

G. Vannelli, L. Adorini, M. Marini, 2007 .

Tanshinone ⅡA inhibits VSMC inflammation and proliferation in vivo and in vitro by downregulating miR-712-5p expression.

Bin Zheng, J. Wen, Tian-Rui Wang, 2020, European journal of pharmacology.