Nicholas F Brown

Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates

N. Moss, S. Weldon, J. Parmentier, 2016, The Journal of Pharmacology and Experimental Therapeutics.

The Aldosterone Synthase Inhibitor FAD286 is Suitable for Lowering Aldosterone Levels in ZDF Rats but not in db/db Mice

S. Bornstein, G. Eisenhofer, S. Weldon, 2017, Hormone and Metabolic Research.

Aldosterone Synthase Inhibition Improves Glucose Tolerance in Zucker Diabetic Fatty (ZDF) Rats.

S. Bornstein, G. Eisenhofer, A. Deussen, 2016, Endocrinology.

Elevated Steroid Hormone Production in the db/db Mouse Model of Obesity and Type 2 Diabetes

S. Bornstein, G. Eisenhofer, S. Weldon, 2016, Hormone and Metabolic Research.

Inhibitors of Aldosterone Synthase.

S. Weldon, Nicholas F Brown, 2019, Vitamins and hormones.

Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science

T. Fox, C. Tautermann, C. Hoenke, 2023, Journal of medicinal chemistry.

Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells

S. Bornstein, G. Eisenhofer, C. Ziegler, 2017, Hormone and Metabolic Research.

Impact of Dietary Sodium Reduction on the Development of Obesity and Type 2 Diabetes in db/db Mice

S. Bornstein, C. Reeps, G. Eisenhofer, 2021, Hormone and Metabolic Research.

Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity.

N. Moss, D. Goldberg, S. Weldon, 2017, Bioorganic & medicinal chemistry letters.