H. Akbar

发表

A Novel Small Molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose Mimics the Antiplatelet Actions of Insulin

Xiaozhuo Chen, J. Akkerman, R. Perveen, 2011, PloS one.

Investigation of the Role of Arachidonic Acid in Platelet Function and Mechanisms for Suppression of Prostaglandin Biosynthesis

N. Ardlie, H. Akbar, 1978, British journal of haematology.

Small molecule targeting the Rac1‐NOX2 interaction prevents collagen‐related peptide and thrombin‐induced reactive oxygen species generation and platelet activation

W. Bergmeier, N. Tandon, X. Duan, 2018, Journal of thrombosis and haemostasis : JTH.

A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo

Shiyong Wu, Xiaozhuo Chen, Lingying Tong, 2012, Molecular Cancer Therapeutics.

Therapeutic Discovery A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis , Induces Cell-Cycle Arrest , and Inhibits Cancer Cell Growth In Vitro and In Vivo

Shiyong Wu, Xiaozhuo Chen, Lingying Tong, 2012 .

Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation

J. Cancelas, X. Shang, K. Funk, 2007, Journal of thrombosis and haemostasis : JTH.

Rho GTPase Signaling in Platelet Regulation and Implication for Antiplatelet Therapies

J. Cancelas, Y. Zheng, H. Akbar, 2023, International journal of molecular sciences.

Towards increasing shelf life and haemostatic potency of stored platelet concentrates

Shailaja N Hegde, Yi Zheng, J. Cancelas, 2018, Current opinion in hematology.

Evidence that Collagen Releases Human Platelet Constituents by Two Different Mechanisms

N. Ardlie, H. Akbar, 1976, British journal of haematology.

Structure–Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents

J. Cancelas, Y. Zheng, W. Seibel, 2023, International journal of molecular sciences.

Antiplatelet actions of trimetoquinol isomers: evidence for inhibition of a prostaglandin-independent pathway of platelet aggregation.

D. Miller, D. Feller, H. Akbar, 1982, Biochemical pharmacology.

Investigation of the effects of phospholipase C on human platelets: evidence that aggregation induced by phospholipase C is independent of prostaglandin generation, released ADP and is modulated by cyclic AMP.

D. Miller, D. Feller, H. Akbar, 1982, Thrombosis research.

RhoA and Rac1 GTPases Differentially Regulate Agonist-Receptor Mediated Reactive Oxygen Species Generation in Platelets

Yi Zheng, X. Duan, A. Davis, 2016, PloS one.

HUMAN PLATELET ACTIVATION BY BACTERIAL PHOSPHOLIPASE C: MECHANISM OF INHIBITION BY FLURAZEPAM

K. Anwer, K. Romstedt, Huzoor-Akbar, 1988, Thrombosis and Haemostasis.

Rational design and applications of a Rac GTPase-specific small molecule inhibitor.

David A. Williams, Yi Zheng, J. Cancelas, 2006, Methods in enzymology.

Gene Targeting Implicates Cdc42 GTPase in GPVI and Non-GPVI Mediated Platelet Filopodia Formation, Secretion and Aggregation

Yi Zheng, M. Berryman, N. Tandon, 2011, PloS one.

Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis

Yi Zheng, M. Holinstat, M. Berryman, 2021, Scientific Reports.