P. Bell

发表

Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct

D. Eaton, M. Bunni, Takamitsu Saigusa, 2019 .

The Exocyst Protein Sec10 Interacts with Polycystin-2 and Knockdown Causes PKD-Phenotypes

K. Park, J. Lipschutz, R. Burdine, 2011, PLoS genetics.

Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors.

B. Siroky, R. Fenton, Takamitsu Saigusa, 2012, American journal of physiology. Renal physiology.

Cilia movement regulates expression of the Raf-1 kinase inhibitor protein.

M. Janech, J. Arthur, Kelli M. Sas, 2011, American journal of physiology. Renal physiology.

Renal cell-to-cell communication via extracellular ATP.

P. Komlósi, A. Fintha, P. Bell, 2005, Physiology.

Proteomic analysis of cerebrospinal fluid in California sea lions (Zalophus californianus) with domoic acid toxicosis identifies proteins associated with neurodegeneration

Benjamin A. Neely, M. Janech, J. Arthur, 2015, Proteomics.

Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes.

D. Benos, P. Komlósi, G. Kovacs, 2005, American journal of physiology. Cell physiology.

Cellular mechanisms of WNK4-mediated regulation of ion transport proteins in the distal tubule.

P. Bell, J.-B. Peng, 2006, Kidney international.

Improvement of blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension.

D. Warnock, P. Bell, 2005, Hypertension.

Autoregulatory responses of superficial nephrons and their association with sodium excretion during arterial pressure alterations in the dog.

L. Navar, T. Burke, P. Bell, 1977, Circulation research.

Bilateral Renal Function Responses to Converting Enzyme Inhibitor (SQ 20,881) in Two‐Kidney, One Clip Goldblatt Hypertensive Rats

Wann-Chu Huang, D. Ploth, J. Work, 1981, Hypertension.

Evidence for apical sodium proton exchange in macula densa cells.

J. Lapointe, M. Higdon, P. Bell, 1995, Kidney international.

Angiotensin II stimulates macula densa basolateral sodium/hydrogen exchange via type 1 angiotensin II receptors.

J. Peti-Peterdi, P. Bell, 1999, Journal of the American Society of Nephrology : JASN.

TRPP2 and TRPV4 Form an EGF-Activated Calcium Permeable Channel at the Apical Membrane of Renal Collecting Duct Cells

P. Komlósi, B. Nilius, Jia-ning Zhang, 2013, PloS one.

Regulation of mesangial cell Na+/Ca2+ exchanger isoforms

B. Siroky, I. Williams, G. Kovacs, 2004, Journal of cellular physiology.

Transport and regulatory properties of the apical Na-K-2Cl cotransporter of macula densa cells.

J. Lapointe, P. Bell, M. Laamarti, 1998, The American journal of physiology.

CHARACTERISTICS OF MEMBRANE TRANSPORT PROCESSES OF MACULA DENSA CELLS

J. Lapointe, P. Bell, 1997, Clinical and experimental pharmacology & physiology.

Activation of Na:2Cl:K cotransport by luminal chloride in macula densa cells.

J. Lapointe, P. Bell, B. Fowler, 1995, Kidney international.

Apical trypsin increases ion transport and resistance by a phospholipase C-dependent rise of Ca2+.

P. Factor, S. Matalon, B. Siroky, 2005, American journal of physiology. Lung cellular and molecular physiology.

Influence of Converting Enzyme Inhibition on Renal Hemodynamics and Glomerular Dynamics in Sodiumhyphenrestricted Dogs

L. Navar, Wann-Chu Huang, D. Jirakulsomchok, 1982, Hypertension.

Glomerular filtration dynamics in the dog during elevated plasma colloid osmotic pressure.

L. Navar, C. Thomas, P. Bell, 1979, Kidney international.

Evaluation of the single nephron glomerular filtration coefficient in the dog.

L. Navar, R. H. Williams, P. Bell, 1977, Kidney international.

Glomerular filtration dynamics during renal vasodilation with acetylcholine in the dog.

L. Navar, F. Knox, C. Ott, 1983, The American journal of physiology.

Impaired renal blood flow autoregulation in ischemic acute renal failure.

L. Navar, P. Adams, F. Adams, 1980, Kidney international.

Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.

M. Bilgen, L. Guay-Woodford, B. Siroky, 2011, Journal of the American Society of Nephrology : JASN.

A non-radioactive fluorescent method for measuring protein kinase C activity.

S. T. Christian, J. Isbell, P. Bell, 1995, Life sciences.

Macula densa Na 1 / H 1 exchange activities mediated by apical NHE 2 and basolateral NHE 4 isoforms

Z. Bebők, D. Warnock, D. Abrahamson, 2000 .

Amyloid beta peptide 1-40 stimulates the Na+/Ca2+ exchange activity of SNCX.

P. Komlósi, B. Siroky, G. Kovacs, 2005, Current neurovascular research.

Glomerular and Renal Hemodynamics During Converting Enzyme Inhibition (SQ20,881) in the Dog

L. Navar, C. Thomas, D. Ploth, 1979, Hypertension.

Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells

Z. Bebők, Wei Wang, L. Guay-Woodford, 2022 .

Evaluation of prostaglandins as mediators of tubuloglomerular feedback.

L. Navar, P. Bell, M. Franco, 1988, The American journal of physiology.

Intrarenal feedback control of glomerular filtration rate

L. Navar, P. Bell, 1982 .

Renal sodium/calcium exchange; a vasodilator that is defective in salt-sensitive hypertension.

M. T. Unlap, P. Bell, N. Mashburn, 2000, Acta physiologica Scandinavica.

Renal arteriolar Na+/Ca2+ exchange in salt-sensitive hypertension.

J. Lewis, M. T. Unlap, L. Nelson, 1999, The American journal of physiology.

Renal arteriolar Na 1 /Ca 2 1 exchange in salt-sensitive hypertension

M. T. Unlap, L. Nelson, P. Bell, 1999 .

Altered sodium-calcium exchange in afferent arterioles of the spontaneously hypertensive rat.

L. Nelson, P. Bell, N. Mashburn, 1996, Kidney international.

Characterization of sodium-calcium exchange in rabbit renal arterioles.

P. Carmines, L. Nelson, P. Bell, 1996, Kidney international.

Fibrosis--a common pathway to organ injury and failure.

Don C Rockey, D. Rockey, Joseph A. Hill, 2015, The New England journal of medicine.

Macula densa basolateral ATP release is regulated by luminal [NaCl] and dietary salt intake.

P. D. Bell, P. Komlósi, L. Rosivall, 2004, American journal of physiology. Renal physiology.

Extracellular Zinc and ATP Restore Chloride Secretion across Cystic Fibrosis Airway Epithelia by Triggering Calcium Entry*

J. Clancy, Z. Bebők, E. Schwiebert, 2004, Journal of Biological Chemistry.

Na+/Ca2+ Exchanger: Target for Oxidative Stress in Salt-Sensitive Hypertension

P. Komlósi, B. Siroky, I. Williams, 2003, Hypertension.

Luminal NaCl delivery regulates basolateral PGE2 release from macula densa cells.

P. Komlósi, M. Breyer, A. Schneider, 2003, The Journal of clinical investigation.

Impaired ability of the Na+/Ca2+ exchanger from the Dahl/Rapp salt-sensitive rat to regulate cytosolic calcium.

P. D. Bell, E. Schwiebert, B. Siroky, 2003, American journal of physiology. Renal physiology.

Sustained Calcium Entry through P2X Nucleotide Receptor Channels in Human Airway Epithelial Cells*

E. Schwiebert, J. Peti-Peterdi, A. Zsembery, 2003, The Journal of Biological Chemistry.

Macula densa cell signaling.

P. D. Bell, J. Peti-Peterdi, J. Lapointe, 2003, Annual review of physiology.

Direct measurement of basolateral membrane potentials from cells of the macula densa.

J. Lapointe, J. Cardinal, P. Bell, 1989, The American journal of physiology.

ATP as a mediator of macula densa cell signalling

P. Komlósi, Zhi-ren Zhang, P. Bell, 2009, Purinergic Signalling.

Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals

B. Yoder, P. Komlósi, E. Schwiebert, 2007, Purinergic Signalling.

Romancing the macula densa at UAB.

L. G. Navar, P. Bell, L. Navar, 2004, Kidney international. Supplement.

Macula densa cell signaling involves ATP release through a maxi anion channel

P. D. Bell, G. Kovacs, J. Peti-Peterdi, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys.

L. Guay-Woodford, D. Wallace, J. Grantham, 2002, American journal of physiology. Renal physiology.

Effect of adenosine A1 analogue on tubuloglomerular feedback mechanism.

L. Navar, P. Bell, M. Franco, 1989, The American journal of physiology.

Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia.

L. Guay-Woodford, B. Yoder, M. O. Bevensee, 2006, American journal of physiology. Cell physiology.

The Renal Microcirculation

E. Inscho, T. Pallone, L. G. Navar, 2011 .

Purinergic receptor signaling at the basolateral membrane of macula densa cells.

J. Peti-Peterdi, A. Persson, Ruisheng Liu, 2002, Journal of the American Society of Nephrology : JASN.

The Regulation of Glomerular Filtration Rate in Mammalian Kidneys

A. Evan, L. Navar, P. Bell, 1978 .

Calcium as a mediator of tubuloglomerular feedback.

L. Navar, P. Bell, M. Franco, 1987, Annual review of physiology.

‘Oxidation Inhibits Substrate Proteolysis by Calpain I but Not Autolysis*

P. D. Bell, G. Johnson, J. Elce, 1997, The Journal of Biological Chemistry.

Altered protein kinase C activation of Na+/Ca2+exchange in mesangial cells from salt-sensitive rats.

G. Johnson, M. T. Unlap, P. Bell, 1999, American journal of physiology. Renal physiology.

Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes

R. Frizzell, T. Tedder, L. Zhou, 1993, The Journal of cell biology.

Evidence for pericyte origin of TSC-associated renal angiomyolipomas and implications for angiotensin receptor inhibition therapy.

Z. Tsuchihashi, B. Siroky, Hong Yin, 2014, American journal of physiology. Renal physiology.

An inducible CiliaGFP mouse model for in vivo visualization and analysis of cilia in live tissue

R. Kesterson, B. Yoder, Erik B. Malarkey, 2013, Cilia.

Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.

P. D. Bell, G. Hardiman, E. Hazard, 2020, Kidney360.

Telomerase immortalization of principal cells from mouse collecting duct.

K. Keyser, L. Guay-Woodford, C. Haycraft, 2010, American journal of physiology. Renal physiology.

Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus

B. Yoder, Boglárka Banizs, P. Komlósi, 2005, Development.

Tubuloglomerular feedback mechanisms in nephron segments beyond the macula densa

P. D. Bell, P. Komlósi, Zhi-ren Zhang, 2009, Current opinion in nephrology and hypertension.

Altered pHi regulation and Na+/HCO3− transporter activity in choroid plexus of cilia-defective Tg737orpk mutant mouse

P. D. Bell, B. Yoder, Boglárka Banizs, 2007 .

Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse.

P. D. Bell, B. Yoder, Boglárka Banizs, 2007, American journal of physiology. Cell physiology.

Altered intracellular pH regulation and Na + / HCO 3-transporter activity in choroid plexus of the cilia defective Tg 737 orpk mutant mouse

P. D. Bell, B. Yoder, Boglárka Banizs, 2006 .

Influence of perfusate osmolality on stop-flow pressure feedback responses in the dog.

P. D. Bell, L. Navar, C. Thomas, 1978, The American journal of physiology.

Permeability of the macula densa basement membrane area to high molecular weight molecules.

P. S. St. John, D. Abrahamson, P. Bell, 1992, Renal physiology and biochemistry.

Cytoplasmic calcium in the mediation of macula densa tubulo-glomerular feedback responses.

L. Navar, P. Bell, 1982, Science.

Fibrosis--A Common Pathway to Organ Injury and Failure.

D. Rockey, Joseph A. Hill, P. Bell, 2015, The New England journal of medicine.

Intracellular Ca2+ and PKC activation do not inhibit Na+ and water transport in rat CCD.

J. Schafer, P. Bell, L. Chen, 1993, The American journal of physiology.

Centrobin-mediated Regulation of the Centrosomal Protein 4.1-associated Protein (CPAP) Level Limits Centriole Length during Elongation Stage*

Zihai Li, R. Gudi, C. Vasu, 2015, The Journal of Biological Chemistry.

Role of cytosolic Ca in renal tubule damage induced by anoxia.

L. Mandel, P. Vilaro, M. Sgambati, 1991, The American journal of physiology.

Angiotensin I Conversion to Angiotensin II Stimulates Cortical Collecting Duct Sodium Transport

D. Warnock, P. Komlósi, L. Rosivall, 2003, Hypertension.

Characterization of basolateral chloride/bicarbonate exchange in macula densa cells.

P. Komlósi, J. Peti-Peterdi, S. Frische, 2005, American journal of physiology. Renal physiology.

Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors.

D. Warnock, J. Peti-Peterdi, P. Bell, 2002, Journal of the American Society of Nephrology : JASN.

Regulation of macula densa Na:H exchange by angiotensin II.

J. Peti-Peterdi, P. Bell, 1998, Kidney international.

Novel regulation of cell [Na(+)] in macula densa cells: apical Na(+) recycling by H-K-ATPase.

Z. Bebők, J. Peti-Peterdi, J. Lapointe, 2002, American journal of physiology. Renal physiology.

Calcium-activated nonselective cationic channel in macula densa cells.

R. Sabirov, Y. Okada, J. Lapointe, 2003, American journal of physiology. Renal physiology.

Basic properties and potential regulators of the apical K+ channel in macula densa cells

J. Lapointe, P. Bell, A. Laamarti, 1994, The Journal of general physiology.

Basolateral ionic permeabilities of macula densa cells.

J. Lapointe, J. Cardinal, P. Bell, 1991, The American journal of physiology.

Direct evidence for apical Na+:2Cl-:K+ cotransport in macula densa cells.

J. Lapointe, J. Cardinal, P. Bell, 1990, The American journal of physiology.

Direct visualization of the isolated and perfused macula densa.

K. Kirk, M. Ribadeneira, D. Barfuss, 1985, The American journal of physiology.

Real-time imaging of the living kidney juxtaglomerular apparatus with multiphoton microscopy

Shigeru Morishima, Janos Peti-Peterdi, P. D. Bell, 2002, SPIE BiOS.

Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells.

L. Guay-Woodford, B. Yoder, P. Komlósi, 2006, American journal of physiology. Renal physiology.

Ionic transport in macula densa cells.

J. Lapointe, P. Bell, A. Laamarti, 1998, Kidney international. Supplement.

Unraveling the relationship between macula densa cell volume and luminal solute concentration/osmolality.

P. Komlósi, A. Fintha, P. Bell, 2006, Kidney international.

Neuronal nitric oxide synthase: its role and regulation in macula densa cells.

P. Komlósi, L. Rosivall, G. Kovacs, 2003, Journal of the American Society of Nephrology : JASN.

Two-photon excitation fluorescence imaging of the living juxtaglomerular apparatus.

P. D. Bell, J. Peti-Peterdi, Y. Okada, 2002, American journal of physiology. Renal physiology.

Macula densa Na(+)/H(+) exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms.

P. D. Bell, Z. Bebők, D. Warnock, 2000, American journal of physiology. Renal physiology.

Calcium and the Mediation of Tubuloglomerular Feedbacks Signals

M. Higdon, P. Bell, M. Franco, 1988 .

Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors.

L. Rosivall, G. Kovacs, J. Peti-Peterdi, 2002, American journal of physiology. Renal physiology.

Cytosolic [Ca2+] signaling pathway in macula densa cells.

P. D. Bell, J. Peti-Peterdi, P. Bell, 1999, American journal of physiology. Renal physiology.

Current mechanisms of macula densa cell signalling.

P. Komlósi, A. Fintha, P. Bell, 2004, Acta physiologica Scandinavica.

Membrane crosstalk in the mammalian proximal tubule during alterations in transepithelial sodium transport.

L. Garneau, J. Lapointe, J. Cardinal, 1990, The American journal of physiology.

Tubuloglomerular feedback responses during perfusion with nonelectrolyte solutions in the rat.

L. Navar, D. Ploth, C. McLean, 1980, Kidney international.

Intracellular calcium in the transmission of tubuloglomerular feedback signals.

M. Reddington, P. Bell, 1983, The American journal of physiology.

Segmentally distinct effects of depolarization on intracellular [Ca2+] in renal arterioles.

P. Carmines, P. Bell, B. Fowler, 1993, The American journal of physiology.

Relationship between tubulo-glomerular feedback responses and perfusate hypotonicity.

L. Navar, P. Bell, 1982, Kidney international.

Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid.

M. Janech, B. Siroky, J. Bissler, 2014, Journal of the American Society of Nephrology : JASN.

Truncating PKHD1 and PKD2 mutations alter energy metabolism.

J. Parant, S. Barnes, R. Kesterson, 2019, American journal of physiology. Renal physiology.

A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma

F. Radwan, A. Haque, B. Doonan, 2012, Apoptosis.

Role of Intracellular Calcium in the Regulation of Renal Hemodynamics

L. Navar, K. Mitchell, P. Carmines, 1991 .

Angiotensin influences on tubuloglomerular feedback mechanism in hypertensive rats.

P. D. Bell, L. Navar, W. Huang, 1988, Kidney international.

Tubuloglomerular feedback responses in the rat during calmodulin inhibition.

P. Bell, 1986, The American journal of physiology.

Cyclic AMP-calcium interaction in the transmission of tubuloglomerular feedback signals.

P. Bell, 1985, Kidney international.

Renal hemodynamic and autoregulatory responses to acute hypercalcemia.

L. Navar, P. Bell, B. Chomdej, 1977, The American journal of physiology.

Absence of estimated glomerular pressure autoregulation during interrupted distal delivery.

L. Navar, P. Bell, B. Chomdej, 1975, The American journal of physiology.

The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.

R. Weiss, L. Guay-Woodford, B. Hammock, 2015, American journal of physiology. Renal physiology.

Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways.

P. D. Bell, B. Yoder, A. Stenbit, 2014, American journal of physiology. Lung cellular and molecular physiology.

N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct.

J. Sands, J. Klein, S. Steele, 2011, American journal of physiology. Renal physiology.

Molecular pathways and therapies in autosomal-dominant polycystic kidney disease.

Takamitsu Saigusa, P. Bell, P. D. Bell, 2015, Physiology.

ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.

P. D. Bell, H. Abboud, S. Higashiyama, 2014, American journal of physiology. Renal physiology.

An American Physiological Society cross-journal Call for Papers on "Deconstructing organs: Single-cell analyses, decellularized organs, organoids, and organ-on-a-chip models".

Josephine C. Adams, J. Ramirez, A. Marette, 2020, American journal of physiology. Lung cellular and molecular physiology.

MACULA DENSA FEEDBACK REGULATION OF RENAL HEMODYNAMICS AND RENAL AUTOREGULATION

L. Navar, P. Adams, P. Bell, 1981 .

Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKD

Z. Bebők, Wei Wang, L. Guay-Woodford, 2023, bioRxiv.

Influence of bradykinin and papaverine on renal and glomerular hemodynamics in dogs.

L. Navar, C. Thomas, P. Bell, 1982, Renal physiology.

Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model

M. Zile, C. Baicu, A. Mullick, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease

M. Bunni, W. Fitzgibbon, Takamitsu Saigusa, 2015, Physiological reports.

Myocardial cell growth and blood pressure development in neonatal spontaneously hypertensive rats.

P. D. Bell, F. Clubb, S. Bishop, 1987, Laboratory investigation; a journal of technical methods and pathology.

Distal tubular feedback control of renal hemodynamics and autoregulation.

P. D. Bell, L. Navar, D. Ploth, 1980, Annual review of physiology.

Immunolocalization of a microsomal prostaglandin E synthase in rabbit kidney.

P. D. Bell, P. Komlósi, J. Peti-Peterdi, 2003, American journal of physiology. Renal physiology.

DELETION OF AIRWAY CILIA RESULTS IN NON-INFLAMMATORY

P. D. Bell, B. Yoder, A. Stenbit, 2013 .

Cloning of mesangial cell Na(+)/Ca(2+) exchangers from Dahl/Rapp salt-sensitive/resistant rats.

J. Peti-Peterdi, M. T. Unlap, P. Bell, 2000, American journal of physiology. Renal physiology.

Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger.

P. D. Bell, L. Luttrell, Mi-Hye Lee, 2014, American journal of physiology. Cell physiology.

Oscillating cortical thick ascending limb cells at the juxtaglomerular apparatus.

P. D. Bell, Boglárka Banizs, P. Komlósi, 2008, Journal of the American Society of Nephrology : JASN.

Intrarenal Control of Glomerular Filtration: Cellular Mechanisms of Tubuloglomerular Feedback

L. Navar, P. Bell, 1984 .

Transport pathways in macula densa cells.

J. Lapointe, J. Cardinal, P. Bell, 1991, Kidney international. Supplement.

Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage.

P. D. Bell, M. Zile, C. Baicu, 2015, American journal of physiology. Renal physiology.

Confocal and two-photon microscopy.

P. D. Bell, J. Peti-Peterdi, János Peti-Peterdi, 2003, Methods in molecular medicine.

ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.

P. D. Bell, H. Abboud, S. Higashiyama, 2014, American journal of physiology. Renal physiology.

Role of feedback mechanism in renal autoregulation and sensing step in feedback pathway.

L. Navar, D. Ploth, P. Bell, 1981, Federation proceedings.

Prostaglandins in the sodium excretory response to altered renal arterial pressure in dogs.

L. Navar, R. Roman, P. Carmines, 1985, The American journal of physiology.

Tubuloglomerular feedback-mediated decreases in glomerular pressure in Munich-Wistar rats.

M. Reddington, L. Navar, D. Ploth, 1984, The American journal of physiology.

Stop-flow pressure feedback responses during reduced renal vascular resistance in the dog.

L. Navar, P. Bell, 1979, The American journal of physiology.