I. Lunde

发表

Exercise training increases protein O‐GlcNAcylation in rat skeletal muscle

I. Sjaastad, O. Sejersted, J. M. Aronsen, 2016, Physiological reports.

Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction

I. Sjaastad, F. Zouein, J. M. Aronsen, 2021, Journal of the American College of Cardiology.

Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice.

I. Sjaastad, G. Christensen, P. Aukrust, 2015, American journal of physiology. Lung cellular and molecular physiology.

hypertrophy and heart failure Cardiac O-GlcNAc signaling is increased in

I. Sjaastad, J. M. Aronsen, H. Kvaløy, 2012 .

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan‐4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure‐overloaded heart

C. Carlson, I. Sjaastad, G. Christensen, 2013, The FEBS journal.

The cardiokine secreted Frizzled‐related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure

L. Tavazzi, R. Latini, G. Christensen, 2014, Journal of internal medicine.

isoforms in cardiomyocytes calcineurin-dependent NFAT transcription factor Angiotensin II and norepinephrine activate specific

W. Linke, I. Sjaastad, G. Christensen, 2015 .

Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes.

C. Carlson, G. Christensen, H. Kvaløy, 2011, Journal of applied physiology.

Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice.

C. Carlson, I. Sjaastad, G. Christensen, 2015, Cardiovascular research.

Exercise training during childhood and adolescence is associated with favorable diastolic function in hypertrophic cardiomyopathy.

T. Edvardsen, K. Haugaa, M. Stokke, 2022, International journal of cardiology.

Wnt5a is elevated in heart failure and affects cardiac fibroblast function

G. Christensen, S. Aakhus, T. Lekva, 2017, Journal of Molecular Medicine.

Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

G. Christensen, S. Aakhus, T. Ueland, 2017, Scientific Reports.

Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf.

J. Seidman, C. Seidman, H. Wakimoto, 2019, Circulation research.

The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload

I. Sjaastad, S. Nygård, G. Christensen, 2019, Scientific Reports.

MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

J. Seidman, H. Watkins, C. Seidman, 2018, bioRxiv.

Title : Hypertrophic Cardiomyopathy Mutations in MYBPC 3 Dysregulate Myosin : Implications for Therapy

J. Seidman, H. Watkins, H. Wakimoto, 2018 .

Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia

C. Carlson, I. Sjaastad, S. Lehnart, 2019, Circulation. Arrhythmia and electrophysiology.

Syndecan‐4 Protects the Heart From the Profibrotic Effects of Thrombin‐Cleaved Osteopontin

A. McCulloch, C. Carlson, I. Sjaastad, 2020, Journal of the American Heart Association.

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.

C. Carlson, I. Sjaastad, G. Christensen, 2013, Journal of molecular and cellular cardiology.

Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice.

I. Sjaastad, G. Christensen, J. M. Aronsen, 2015, Journal of molecular and cellular cardiology.

Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy

C. Carlson, I. Sjaastad, G. Christensen, 2022, Molecular Biology Reports.

Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis

P. Nilsson, S. Aakhus, T. Ueland, 2019, The Journal of Immunology.

Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement

C. Carlson, I. Sjaastad, G. Christensen, 2022, Frontiers in Molecular Medicine.

Integrin α11β1 and syndecan-4 dual receptor ablation attenuates cardiac hypertrophy in the pressure overloaded heart.

I. Sjaastad, G. Christensen, H. Stenmark, 2022, American journal of physiology. Heart and circulatory physiology.

Syndecans in heart fibrosis

G. Christensen, I. Lunde, K. Herum, 2016, Cell and Tissue Research.

Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids

I. Sjaastad, G. Nilsson, Ø. Øverli, 2017, Journal of Experimental Biology.

Cortisol response to stress is associated with myocardial remodeling in salmonid fishes

G. Christensen, H. Røsjø, G. Nilsson, 2011, Journal of Experimental Biology.

Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle.

I. Sjaastad, S. Nygård, G. Christensen, 2012, Journal of applied physiology.

Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology

M. Mayr, G. Filippatos, S. Heymans, 2019, European journal of heart failure.

The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart

A. McCulloch, G. Christensen, I. G. Lunde, 2017, Journal of clinical medicine.

Elevated temperature reduces the respiratory scope of coral reef fishes

G. Nilsson, P. Munday, I. Lunde, 2009 .

Genetic Variants Associated With Cancer Therapy–Induced Cardiomyopathy

Parth N. Patel, J. Seidman, D. O’Regan, 2019, Circulation.

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

Christine E Seidman, Sakthivel Sadayappan, J. Seidman, 2019, Science Translational Medicine.

Endothelin-1 in the Human Myocardium and Circulating Plasma: Evaluation before, during and after Correction of Aortic Stenosis with Aortic Valve Replacement

G. Christensen, T. Tønnessen, T. Husebye, 2012, Cardiology.

Increased hypertrophic response with increased mechanical load in skeletal muscles receiving identical activity patterns.

K. Gundersen, J. Bruusgaard, S. Ellefsen, 2016, American journal of physiology. Cell physiology.

Trophic Structure and Community Stability in an Overfished Ecosystem

V. Braithwaite, G. Nilsson, A. Sweetman, 2010, Science.

Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease.

G. Christensen, Geir Christensen, Ida G Lunde, 2019, Matrix biology : journal of the International Society for Matrix Biology.

The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts

G. Christensen, T. Tønnessen, S. Apte, 2021, Scientific Reports.

Hypoxia inducible factor 1α links fast‐patterned muscle activity and fast muscle phenotype in rats

K. Gundersen, J. Bruusgaard, S. Ellefsen, 2011, The Journal of physiology.

Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload

I. Sjaastad, G. Christensen, I. G. Lunde, 2020, Cardiology.

Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli

Biljana Skrbic, Ivar Sjaastad, I. Sjaastad, 2013, The FEBS journal.

Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy

G. Christensen, S. Aakhus, T. Ueland, 2017, Scientific Reports.

The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling

I. Sjaastad, G. Christensen, I. G. Lunde, 2016, PloS one.

The continuous heart failure spectrum: moving beyond an ejection fraction classification.

Thomas Thum, Robert J Mentz, Richard T. Lee, 2019, European heart journal.

The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

Michael Böhm, Piotr Ponikowski, Stephane Heymans, 2017, European journal of heart failure.

Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart.

W. Linke, I. Sjaastad, G. Christensen, 2015, Cardiovascular research.

Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding

C. Carlson, I. Sjaastad, G. Christensen, 2014, PloS one.

Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure.

C. Carlson, I. Sjaastad, G. Christensen, 2012, Physiological genomics.

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology

G. Filippatos, W. Paulus, S. Heymans, 2018, European heart journal.

A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice

I. Sjaastad, G. Christensen, J. M. Aronsen, 2018, Cardiovascular research.

Molecular Basis of Calpain Cleavage and Inactivation of the Sodium-Calcium Exchanger 1 in Heart Failure*

C. Carlson, I. Sjaastad, K. Hodne, 2014, The Journal of Biological Chemistry.

The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy

G. Christensen, S. Aakhus, T. Lekva, 2017, Journal of Cardiovascular Translational Research.

The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling

Jan Magnus Aronsen, Ivar Sjaastad, I. Sjaastad, 2018, PloS one.

PPARδ expression is influenced by muscle activity and induces slow muscle properties in adult rat muscles after somatic gene transfer

A. Buonanno, K. Gundersen, I. Lunde, 2007, The Journal of physiology.

Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

I. Sjaastad, G. Christensen, T. Ueland, 2022, ESC heart failure.

Syndecans in heart fibrosis

G. Christensen, I. Lunde, K. Herum, 2016, Cell and Tissue Research.

Trifecta has lower gradient and less prosthesis-patient mismatch than Mosaic Ultra in the aortic position: A prospective randomized study.

T. Tønnessen, T. Husebye, B. Braathen, 2019, The Journal of thoracic and cardiovascular surgery.

ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload

Daniel R. Martin, S. Heymans, I. Sjaastad, 2022, Communications biology.

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway

S. Djurovic, C. Carlson, I. Sjaastad, 2011, PloS one.

Molecular mechanisms of heart failure : Nuclear Factor of Activated T-cell (NFAT) signaling in myocardial hypertrophy and dysfunction

I. Lunde, 2012 .

Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease

S. Heymans, G. Christensen, T. Tønnessen, 2023, Biomedicines.

Regulation of adult muscle phenotype by PPARδ

M. Thesis, I. Lunde, 2006 .

Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte

W. Linke, O. Sejersted, P. D. de Tombe, 2023, Circulation research.

myocardial infarction without congestion in the mouse from myocardial infarction with pulmonary congestion Echocardiographic parameters discriminating

W. Linke, I. Sjaastad, G. Christensen, 2015 .

Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy

S. Heymans, H. Brunner, H. Wakimoto, 2023, Circulation. Genomic and precision medicine.

Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction

C. Carlson, I. Sjaastad, G. Christensen, 2023, Cardiovascular research.

Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology.

I. V. Van Gelder, G. Hindricks, P. Ponikowski, 2021, European heart journal.

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan‐4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure‐overloaded heart

C. Carlson, I. Sjaastad, G. Christensen, 2013, The FEBS journal.

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.

C. Carlson, I. Sjaastad, G. Christensen, 2013, Journal of molecular and cellular cardiology.

Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia

C. Carlson, I. Sjaastad, S. Lehnart, 2019, Circulation. Arrhythmia and electrophysiology.

The cardiokine secreted Frizzled‐related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure

L. Tavazzi, R. Latini, G. Christensen, 2014, Journal of internal medicine.

Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development

I. Sjaastad, G. Christensen, M. Vistnes, 2023, Matrix biology plus.

Regulation of cardiomyocyte t-tubule structure by preload and afterload: Roles in cardiac compensation and decompensation.

I. Sjaastad, S. Nygård, G. Christensen, 2024, The Journal of physiology.