P. Tombe

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Sex differences in health and disease: brain and heart connections—a special issue

J. Wattanapermpool, T. Pak, P. Tombe, 2013, Pflügers Archiv - European Journal of Physiology.

Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro

P. D. de Tombe, S. Sadayappan, N. Sundaresan, 2012, Journal of Muscle Research and Cell Motility.

Molecular and Integrated Biology of Thin Filament Protein Phosphorylation in Heart Muscle

R. Solaro, M. Sumandea, Tomoyoshi Kobayashi, 2004, Annals of the New York Academy of Sciences.

Troponin Dependent Phosphorylation of Specific Sites on Cardiac − Functional Effects of Rho-Kinase

R. Solaro, C. Warren, Tomoyoshi Kobayashi, 2005 .

Myosin Binding Protein C in the Heart

P. Tombe, 2006 .

Interventricular differences in myofilament function in experimental congestive heart failure

R. Solaro, D. Geenen, L. Harvey, 2011, Pflügers Archiv - European Journal of Physiology.

Novel approaches to determine contractile function of the isolated adult zebrafish ventricular cardiac myocyte

F. B. Pickett, A. V. Dvornikov, O. Alekhina, 2014, The Journal of physiology.

Cardiac myosin binding protein-C: redefining its structure and function

P. D. de Tombe, S. Sadayappan, P. Tombe, 2012, Biophysical Reviews.

Protein kinase Cε induces systolic cardiac failure marked by exhausted inotropic reserve and intact Frank-Starling mechanism

P. Buttrick, D. Geenen, V. Rundell, 2005 .

Cardiac thin filament regulation

Lei Jin, Tomoyoshi Kobayashi, P. Tombe, 2008, Pflügers Archiv - European Journal of Physiology.

Functional Effects of Rho-Kinase (ROCK-II)–Dependent Phosphorylation of Specific Sites on Cardiac Troponin

R. Solaro, C. Warren, Tomoyoshi Kobayashi, 2005 .

Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation

R. Solaro, C. Warren, S. Rajan, 2011, Journal of Muscle Research and Cell Motility.

Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions

B. Wolska, J. Leiden, R. Solaro, 2001, The Journal of physiology.

Ca2+ activation and tension cost in myofilaments from mouse hearts ectopically expressing enteric γ-actin

P. D. de Tombe, J. Lessard, Ajit Kumar, 2002 .

Cardiac myosin binding protein-C: redefining its structure and function

S. Sadayappan, P. Tombe, 2012, Biophysical Reviews.

Determinants of Velocity of Sarcomere Shortening in Mammalian Myocardium

H. E. Keurs, P. Tombe, 1993 .

Troponin I in the murine myocardium: influence on length‐dependent activation and interfilament spacing

T. Irving, B. Wolska, R. Solaro, 2003 .

Sex differences in health and disease: brain and heart connections—a special issue

J. Wattanapermpool, T. Pak, P. Tombe, 2013, Pflügers Archiv: European Journal of Physiology.

Effects of Temperature

H. E. Keurs, P. Tombe, 2005 .

Force and velocity of sarcomere shortening in trabeculae from rat heart. Effects of temperature.

H. Keurs, P. P. Tombe, P. P. De Tombe, 1990 .

Lack of effect of isoproterenol on unloaded velocity of sarcomere shortening in rat cardiac trabeculae.

H. Keurs, P. Tombe, 1991 .

Coronary thrombolysis with and without nifedipine in pigs

P. Hugenholtz, P. Verdouw, P. P. Tombe, 1988, Basic Research in Cardiology.

Ischemia, High-Energy Phosphate Metabolism and Sarcomere Dynamics in Myocardium

H. E. Keurs, J. Bucx, W. Leijendekker, 1988 .

Altered contractile function in heart failure

P. Tombe, 1998 .

Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner

C. D. dos Remedios, S. Sadayappan, D. Warshaw, 2018, Scientific Reports.

Blebbistatin: use as inhibitor of muscle contraction

Alain Lacampagne, Kittipong Tachampa, A. Lacampagne, 2008, Pflügers Archiv - European Journal of Physiology.

Length‐dependent activation in three striated muscle types of the rat

T. Irving, John P. Konhilas, Thomas C. Irving, 2002, The Journal of physiology.

Heart failure: a special issue

J. Velden, P. Tombe, 2014, Pflügers Archiv - European Journal of Physiology.

The velocity of cardiac sarcomere shortening: mechanisms and implications

H. E. Keurs, P. Tombe, 2012, Journal of Muscle Research and Cell Motility.

Sarcomere dynamics in cat cardiac trabeculae.

H. Keurs, P. P. De Tombe, H. E. D. J. Ter Keurs, 1991 .

Cardiac myofilaments: mechanics and regulation.

Pieter P. de Tombe, P. Tombe, 2003 .

Intracellular Localization and Functional Effects of P21-Activated Kinase-1 (Pak1) in Cardiac Myocytes

P. D. de Tombe, R. Solaro, W. Pyle, 2004, Circulation research.

Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T

L. Leinwand, P. D. de Tombe, J. Tardiff, 2001 .

An internal viscous element limits unloaded velocity of sarcomere shortening in rat myocardium.

P. D. de Tombe, P. P. De Tombe, K. E. D. J. Ter Keurs, 1992 .

Cardiac myosin binding protein-C as a central target of cardiac sarcomere signaling: a special mini review series

S. Sadayappan, P. Tombe, 2014, Pflügers Archiv - European Journal of Physiology.

Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro

S. Sadayappan, N. Sundaresan, J. Sarkey, 2012, Journal of Muscle Research and Cell Motility.

Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch

Y. Ait mou, P. P. Tombe, O. Cazorla, 2008, Pflügers Archiv - European Journal of Physiology.

The cytoskeleton and the cellular transduction of mechanical strain in the heart: a special issue

H. Granzier, P. Tombe, 2011, Pflügers Archiv - European Journal of Physiology.

Impact of stretch on sarcomere length variability in isolated fully relaxed rat cardiac myocytes

O. Lookin, O. Cazorla, P. Tombe, 2023, Research square.

Alterations in left ventricular mechanics, energetics, and contractile reserve in experimental heart failure.

D. Kass, D. Burkhoff, W. Hunter, 1992, Circulation research.

Protein kinase A does not alter economy of force maintenance in skinned rat cardiac trabeculae.

P. D. de Tombe, G. Stienen, P. Tombe, 1995, Circulation research.

Cardiac muscle mechanics: Sarcomere length matters

H. E. Keurs, Pieter P. de Tombe, Henk E.D.J. ter Keurs, 2016 .

Structural Changes in Both the Troponin Complex and the Thick Filament May Underlie Myofilament Length Dependent Activation

T. Irving, P. Tombe, Y. A. Mou, 2012 .

Ablation of Ventricular Myosin Regulatory Light Chain Phosphorylation in Mice Causes Cardiac Dysfunction in Situ and Affects Neighboring Myofilament Protein Phosphorylation*

Sarah B. Scruggs, P. D. de Tombe, L. Walker, 2009, Journal of Biological Chemistry.

Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca2+-dependent manner

C. D. dos Remedios, S. Sadayappan, D. Warshaw, 2018, Scientific Reports.

Comparison between the effects of 2–3 dutanedione monoxime (BDM) and calcium chloride on myocardial oxygen consumption

D. Burkhoff, W. Hunter, P. Tombe, 1992 .

Mechanisms of Ca2+ handling in zebrafish ventricular myocytes

A. Zima, E. Bovo, A. V. Dvornikov, 2013, Pflügers Archiv - European Journal of Physiology.

Nogo-A knockdown inhibits hypoxia/reoxygenation-induced activation of mitochondrial-dependent apoptosis in cardiomyocytes.

A. Zima, E. Bovo, Jody L. Martin, 2011, Journal of molecular and cellular cardiology.

Cardiac myosin binding protein-C as a central target of cardiac sarcomere signaling: a special mini review series

S. Sadayappan, P. Tombe, 2013, Pflügers Archiv - European Journal of Physiology.

Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin.

P. D. de Tombe, B. Wolska, R. Solaro, 1999, Circulation research.

Losartan prevents contractile dysfunction in rat myocardium after left ventricular myocardial infarction.

P. D. de Tombe, M. Daniëls, R. Keller, 2001, American journal of physiology. Heart and circulatory physiology.

Skeletal myosin binding protein-C isoforms regulate thin filament Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca(2+)-dependent manner activity in a Ca(2+)-dependent manner us know how access to this document benefits you.

S. Sadayappan, D. Warshaw, Amy Li, 2022 .

Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium.

T. Irving, R. Fischetti, P. D. de Tombe, 2000, American journal of physiology. Heart and circulatory physiology.

Effects of a myofilament calcium sensitizer on left ventricular systolic and diastolic function in rats with volume overload heart failure.

P. D. de Tombe, S. Sadayappan, M. Cismowski, 2014, American journal of physiology. Heart and circulatory physiology.

New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I.

Sarah B. Scruggs, P. Ping, P. D. de Tombe, 2013, Biochimica et biophysica acta.

Cross-bridge kinetics in rat myocardium: effect of sarcomere length and calcium activation.

P. D. de Tombe, P P De Tombe, P. Janssen, 2000, American journal of physiology. Heart and circulatory physiology.

Intracellular Localization and Functional Effects of P 21-Activated Kinase-1 ( Pak 1 ) in Cardiac Myocytes

R. Solaro, W. Pyle, Y. Ke, 2003 .

Left ventricular myofilament dysfunction in rat experimental hypertrophy and congestive heart failure.

P. D. de Tombe, L. Walker, R. Solaro, 2006, American journal of physiology. Heart and circulatory physiology.