I. Bruzual

发表

Construction of a cassette for cloning and analysis of replicons.

G. Alonso, J. Campos, I. Bruzual, 2000, Acta cientifica venezolana.

Cloning and characterization of a replicon region of the IncHII plasmid pHH1457.

G. Alonso, V. Rodríguez-Lemoine, J. Campos, 1999, FEMS microbiology letters.

Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.

Dustin J Maly, W. Hol, M. Parsons, 2016, Journal of medicinal chemistry.

SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1

Dustin J Maly, W. Hol, M. Parsons, 2015, ACS medicinal chemistry letters.

Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis.

Dustin J Maly, M. Parsons, A. DeRocher, 2018, The Journal of infectious diseases.

An MDR1 promoter allele with higher promoter activity is common in clinically isolated strains of Candida albicans

C. Kumamoto, I. Bruzual, 2011, Molecular Genetics and Genomics.

Identification and properties of plasma membrane azole efflux pumps from the pathogenic fungi Cryptococcus gattii and Cryptococcus neoformans.

B. Wong, Charles E. Gast, I. Bruzual, 2015, The Journal of antimicrobial chemotherapy.

Azole Resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the Role of ERG11

B. Wong, Charles E. Gast, I. Bruzual, 2013, Antimicrobial Agents and Chemotherapy.

Characterization of plasmid MIP233 (IncHI3) of the H complex.

G. Alonso, V. Rodríguez-Lemoine, I. Bruzual, 2002, Research in microbiology.

Biofilm formation by fluconazole-resistant Candida albicans strains is inhibited by fluconazole.

C. Kumamoto, P. Riggle, S. Hadley, 2007, The Journal of antimicrobial chemotherapy.

Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

Alyssa J Miller, L. Zakharov, M. Riscoe, 2020, Antimicrobial Agents and Chemotherapy.

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

M. Foley, P. Rosenthal, P. Bhanot, 2018, Proceedings of the National Academy of Sciences.

Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Choukri Ben Mamoun, S. Africa., L. Bockenstedt, 2016, The Journal of experimental medicine.

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis.

L. Zakharov, M. Riscoe, Aaron Nilsen, 2018, ACS infectious diseases.

Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii

Choukri Ben Mamoun, M. Riscoe, Aaron Nilsen, 2016, Antimicrobial Agents and Chemotherapy.

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

S. Kappe, D. Koop, L. Bleyle, 2019, Malaria Journal.

Azole Resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the Role of ERG11

B. Wong, Charles E. Gast, I. Bruzual, 2013, Antimicrobial Agents and Chemotherapy.