J. P. Schlebach

发表

Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutants

J. T. Ortega, B. Jastrzebska, Andrew G. McKee, 2022, bioRxiv.

Regulators of Viral Frameshifting: More Than RNA Influences Translation Events.

S. Mukhopadhyay, Wesley D. Penn, J. P. Schlebach, 2020, Annual review of virology.

Bicelle size modulates the rate of bacteriorhodopsin folding

Joshua J. Ziarek, J. P. Schlebach, Timothy C Gruenhagen, 2018, Protein science : a publication of the Protein Society.

Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal

J. Meiler, J. T. Ortega, B. Jastrzebska, 2022, bioRxiv.

Molecular basis for the evolved instability of a human G-protein coupled receptor

J. Meiler, Joshua J. Ziarek, B. Bender, 2019, bioRxiv.

Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis

C. Sanders, J. Capra, Wesley D. Penn, 2019, Chemical reviews.

Coordination of -1 programmed ribosomal frameshifting by transcript and nascent chain features revealed by deep mutational scanning

Thomas F. Miller, S. Mukhopadhyay, M. Zimmer, 2021, bioRxiv.

Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants

J. Meiler, Karen Noguera, E. McDonald, 2022, bioRxiv.

Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning

J. Meiler, D. Rusch, C. Hemmerich, 2020, Science Advances.

The safety dance: biophysics of membrane protein folding and misfolding in a cellular context

C. Sanders, J. P. Schlebach, 2014, Quarterly Reviews of Biophysics.

A pH-Mediated Topological Switch within the N-Terminal Domain of Human Caveolin-3.

C. Sanders, Dungeng Peng, Zhenwei Lu, 2016, Biophysical journal.

Peripheral myelin protein 22 alters membrane architecture

Kathleen F. Mittendorf, C. Sanders, E. Wright, 2017, Science Advances.

Glycosylation limits forward trafficking of the tetraspan membrane protein PMP22

C. Sanders, L. Plate, J. P. Schlebach, 2020, bioRxiv.

Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22

Kathleen F. Mittendorf, C. Sanders, B. Carter, 2015, Journal of the American Chemical Society.

Chromenone derivatives as novel pharmacological chaperones for retinitis pigmentosa-linked rod opsin mutants.

J. T. Ortega, B. Jastrzebska, Andrew G. McKee, 2022, Human molecular genetics.

Ribosomal Frameshifting Selectively Modulates the Biosynthesis, Assembly, and Function of a Misfolded CFTR Variant

E. McDonald, L. Plate, Andrew G. McKee, 2023, bioRxiv.

Cotranslational folding stimulates programmed ribosomal frameshifting in the alphavirus structural polyprotein

Thomas F. Miller, S. Mukhopadhyay, M. Zimmer, 2019, The Journal of Biological Chemistry.

Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.

J. Meiler, B. Jastrzebska, Bian Li, 2018, Journal of the American Chemical Society.

Probing membrane protein unfolding with pulse proteolysis.

J. Bowie, Chiwook Park, N. Joh, 2011, Journal of molecular biology.

Author ' s personal copy COMMUNICATION ProbingMembraneProteinUnfoldingwithPulseProteolysis

J. Bowie, Chiwook Park, N. Joh, 2011 .

The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State.

B. Jastrzebska, William D. Comar, Adam W. Smith, 2018, Biochemistry.

Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein.

Kathleen F. Mittendorf, C. Sanders, B. Kroncke, 2013, Biochemistry.

Revisiting the folding kinetics of bacteriorhodopsin

J. Bowie, Chiwook Park, Zheng Cao, 2012, Protein science : a publication of the Protein Society.

A protein folding intermediate pulls its weight

J. P. Schlebach, 2020, The Journal of Biological Chemistry.

Influence of Pathogenic Mutations on the Energetics of Translocon-Mediated Bilayer Integration of Transmembrane Helices

C. Sanders, J. P. Schlebach, 2015, The Journal of Membrane Biology.

Disease-linked supertrafficking of a potassium channel

C. Sanders, J. Meiler, A. George, 2021, The Journal of biological chemistry.

Disease-Linked Super-Trafficking of a Mutant Potassium Channel

C. Sanders, J. Meiler, A. George, 2020, bioRxiv.

Bacteriorhodopsin Folds through a Poorly Organized Transition State

J. Bowie, Chiwook Park, Nicholas B. Woodall, 2014, Journal of the American Chemical Society.

Ions at the Interface: Pushing the pK of pHLIP.

J. P. Schlebach, 2019, Biophysical journal.

Classification of the Molecular Defects Associated with Pathogenic Variants of the SLC6A8 Creatine Transporter.

Richard Bonneau, Julia Koehler Leman, Wesley D. Penn, 2020, Biochemistry.

Towards Generalizable Predictions for the Effects of Mutations on G-Protein Coupled Receptor Expression

Jeffrey L. Mendenhall, J. Meiler, Andrew G. McKee, 2021, bioRxiv.

Structure-Activity Relationship Study of Cannabidiol-Based Analogs as Negative Allosteric Modulators of the μ-Opioid Receptor.

M. VanNieuwenhze, A. Straiker, J. P. Schlebach, 2023, Journal of medicinal chemistry.

Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles

C. Sanders, A. Kenworthy, Charles A. Day, 2016, Biochemistry.

Modest Effects of Lipid Modifications on the Structure of Caveolin-3

C. Sanders, Arina Hadziselimovic, Dungeng Peng, 2014, Biochemistry.

Systematic profiling of temperature- and retinal-sensitive rhodopsin variants by deep mutational scanning

J. Meiler, J. T. Ortega, B. Jastrzebska, 2021, bioRxiv.

Simplified proteomics approach to discover protein–ligand interactions

Chiwook Park, Y. Chang, J. P. Schlebach, 2012, Protein science : a publication of the Protein Society.

Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein Variants

J. Meiler, D. Rusch, Andrew G. McKee, 2023, bioRxiv.

Divergent Pairwise Epistasis in the Context of Unstable Membrane Protein

Hope J. Woods, Andrew G. McKee, Wesley D. Penn, 2023 .

Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants

E. McDonald, J. P. Schlebach, Kathryn E. Oliver, 2024, PLoS ONE.

Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants

E. McDonald, J. P. Schlebach, Kathryn E. Oliver, 2023, bioRxiv.

Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state.

J. Bowie, Chiwook Park, Zheng Cao, 2012, Biochimica et biophysica acta.

General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants.

J. Meiler, Karen Noguera, E. McDonald, 2023, Cell chemical biology.