Douglas B Kell

发表

Fast automatic registration of images using the phase of a complex wavelet transform: application to proteome gels.

Andrew M Woodward, Jem J Rowland, Douglas B Kell, 2004, The Analyst.

Enzyme kinetics informatics: from instrument to browser

Neil Swainston, Kieran Smallbone, Renate Kania, 2010, The FEBS journal.

Deep learning and generative methods in cheminformatics and chemical biology: navigating small molecule space intelligently

Soumitra Samanta, Neil Swainston, Douglas B Kell, 2020, The Biochemical journal.

Information-theoretic sensitivity analysis: a general method for credit assignment in complex networks

Martin Brown, Stefano Panzeri, Niklas Lüdtke, 2007, Journal of The Royal Society Interface.

Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.

Douglas B Kell, D. Kell, 2006, The FEBS journal.

SpeedyGenes: Exploiting an Improved Gene Synthesis Method for the Efficient Production of Synthetic Protein Libraries for Directed Evolution.

Neil Swainston, Andrew Currin, Douglas B Kell, 2017, Methods in molecular biology.

Insights into the behaviour of systems biology models from dynamic sensitivity and identifiability analysis: a case study of an NF-kappaB signalling pathway.

Hong Wang, Martin Brown, Joshua D. Knowles, 2006, Molecular bioSystems.

Metabolomic biomarkers: search, discovery and validation '… we will have good systems biology models of metabolism and metabolomics long before the same can be said of gene or protein networks.'

Douglas B Kell, D. Kell, 2007 .

The virtual human: Towards a global systems biology of multiscale, distributed biochemical network models

Douglas B Kell, D. Kell, 2007, IUBMB life.

Controlled vocabularies and semantics in systems biology

Michel Dumontier, Dagmar Waltemath, Michael Hucka, 2011, Molecular systems biology.

Estimation of Microbial Viability Using Flow Cytometry

Douglas B Kell, Hazel M Davey, Dieter H Weichart, 2004, Current protocols in cytometry.

An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals

Carole Goble, Neil Swainston, Rainer Breitling, 2018, Communications Biology.

Erratum: The Systems Biology Graphical Notation

Samik Ghosh, Yukiko Matsuoka, Hiroaki Kitano, 2009, Nature Biotechnology.

Metabolomic biomarkers: search, discovery and validation

Douglas B Kell, D. Kell, 2007, Expert review of molecular diagnostics.

biochem4j: Integrated and extensible biochemical knowledge through graph databases

Sophia Ananiadou, Pablo Carbonell, Alan R. Williams, 2017, PloS one.

Fast and Flexible Synthesis of Combinatorial Libraries for Directed Evolution.

Neil Swainston, Andrew Currin, Lucy Green, 2018, Methods in enzymology.

VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder

Soumitra Samanta, Neil Swainston, Douglas B Kell, 2020, Molecules.

Text mining and its potential applications in systems biology.

Sophia Ananiadou, Jun-ichi Tsujii, Douglas B Kell, 2006, Trends in biotechnology.

The markup is the model: reasoning about systems biology models in the Semantic Web era.

Pedro Mendes, Douglas B Kell, D. Kell, 2008, Journal of theoretical biology.

Implications of the dominant role of transporters in drug uptake by cells.

Douglas B Kell, Stephen G Oliver, Karin Lanthaler, 2009, Current topics in medicinal chemistry.

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols.

Irena Spasic, David Broadhurst, David I. Ellis, 2008, International journal of epidemiology.

Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast

Douglas B Kell, Stephen G Oliver, Elizabeth Bilsland, 2011, BMC Biology.

Aptamer evolution for array-based diagnostics.

Douglas B Kell, David C Wedge, Philip J R Day, 2009, Analytical biochemistry.

The Cytochrome P450 Complement (CYPome) of Streptomyces coelicolor A3(2)*

Colin J Jackson, Douglas B Kell, D. Kell, 2002, The Journal of Biological Chemistry.

Single-nucleotide polymorphism detection using nanomolar nucleotides and single-molecule fluorescence.

Jem J Rowland, Douglas B Kell, D. Kell, 2004, Analytical biochemistry.

Optimal construction of a fast and accurate polarisable water potential based on multipole moments trained by machine learning.

Douglas B Kell, Paul L A Popelier, D. Kell, 2009, Physical chemistry chemical physics : PCCP.

What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible?

Douglas B Kell, D. Kell, 2015, Trends in pharmacological sciences.

Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability.

Douglas B Kell, Stephen G Oliver, David C Hoyle, 2012, Environmental microbiology.

Proximate parameter tuning for biochemical networks with uncertain kinetic parameters.

Douglas B Kell, Neil Benson, S. J. Wilkinson, 2008, Molecular bioSystems.

Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?

Douglas B Kell, D. Kell, 2012, BioEssays : news and reviews in molecular, cellular and developmental biology.

Breeding crop plants with deep roots: their role in sustainable carbon, nutrient and water sequestration.

Douglas B Kell, D. Kell, 2011, Annals of botany.

Metabolic footprinting as a tool for discriminating between brewing yeasts

Royston Goodacre, Douglas B Kell, Warwick B Dunn, 2007, Yeast.

A proposed framework for the description of plant metabolomics experiments and their results

Nigel W. Hardy, Kazuki Saito, Oliver Fiehn, 2004, Nature Biotechnology.

Genotype-phenotype mapping: genes as computer programs.

Douglas B Kell, D. Kell, 2002, Trends in genetics : TIG.

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells.

Douglas B Kell, D. Kell, E. Pretorius, 2014, Metallomics : integrated biometal science.

Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only.

Douglas B Kell, Stephen G Oliver, Paul D Dobson, 2011, Drug discovery today.

Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics.

Joshua D. Knowles, David Broadhurst, Douglas B Kell, 2007, Analytical chemistry.

Development and performance of a gas chromatography-time-of-flight mass spectrometry analysis for large-scale nontargeted metabolomic studies of human serum.

Joshua D. Knowles, Royston Goodacre, Douglas B Kell, 2009, Analytical chemistry.

Microbes and Alzheimer's Disease.

Hugo Lövheim, Douglas B Kell, George Perry, 2016, Journal of Alzheimer's disease : JAD.

Analysing and Navigating Natural Products Space for Generating Small, Diverse, But Representative Chemical Libraries

Douglas B Kell, Steve O'Hagan, D. Kell, 2018, Biotechnology journal.

Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops.

Nigel W. Hardy, Oliver Fiehn, Janet Taylor, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles.

David Broadhurst, David I. Ellis, Douglas B Kell, 2006, Brain : a journal of neurology.