N. Kishi

CYP 3 A 4 IS A MAJOR ISOFORM RESPONSIBLE FOR OXIDATION OF 7-HYDROXY-D 8-TETRAHYDROCANNABINOL TO 7-OXO-D 8-TETRAHYDROCANNABINOL IN HUMAN LIVER MICROSOMES

I. Yamamoto, Kazuhito Watanabe, T. Matsunaga, 2000 .

Major cytochrome P450 enzyme responsible for oxidation of secondary alcohols to the corresponding ketones in mouse hepatic microsomes. Oxidation of 7-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1998, Drug metabolism and disposition: the biological fate of chemicals.

CYP3A4 Is a Major Isoform Responsible for Oxidation of 7-Hydroxy-Δ8-tetrahydrocannabinol to 7-Oxo-Δ8-tetrahydrocannabinol in Human Liver Microsomes

I. Yamamoto, Kazuhito Watanabe, T. Matsunaga, 2000 .

Oxidation Mechanism of 7-Hydroxy-Δ8-tetrahydrocannabinol and 8-Hydroxy-Δ9-tetrahydrocannabinol to the Corresponding Ketones by CYP3A11

I. Yamamoto, Kazuhito Watanabe, T. Matsunaga, 2001 .

OXIDATION MECHANISM OF 7-HYDROXY-

I. Yamamoto, Kazuhito Watanabe, T. Matsunaga, 2001 .