Tur‐Fu Huang

Tur-Fu Huang, M. Polokoff, R. Gould, 1990, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

A tetrameric glycoprotein Ib-binding protein, agglucetin, from Formosan pit viper: structure and interaction with human platelets

Wen-Jeng Wang, M. Liau, Q. Ling, 2003, Thrombosis and Haemostasis.

Aggretin, a snake venom–derived endothelial integrin α2β1 agonist, induces angiogenesis via expression of vascular endothelial growth factor

C. Chung, Wen-Bin Wu, Tur‐Fu Huang, 2004 .

Butein Inhibits Angiogenesis of Human Endothelial Progenitor Cells via the Translation Dependent Signaling Pathway

Yen-Ling Chen, C. Chung, Chien-Hsin Chang, 2013, Evidence-based complementary and alternative medicine : eCAM.

Ultrasound Stimulates Cyclooxygenase-2 Expression and Increases Bone Formation through Integrin, Focal Adhesion Kinase, Phosphatidylinositol 3-Kinase, and Akt Pathway in Osteoblasts

W. Fu, Tsang-Hai Huang, W. Chuang, 2006, Molecular Pharmacology.

4-Acetylantroquinonol B Suppresses Prostate Cancer Growth and Angiogenesis via a VEGF/PI3K/ERK/mTOR-Dependent Signaling Pathway in Subcutaneous Xenograft and In Vivo Angiogenesis Models

Thomas Y. Hsueh, C. Chung, Yu-Jen Chen, 2022, International journal of molecular sciences.

Characterization of platelet aggregation induced by human breast carcinoma and its inhibition by snake venom peptides, trigramin and rhodostomin

M. Swaim, Tur‐Fu Huang, H. Chiang, 1995, Breast Cancer Research and Treatment.

Triflavin, an Arg‐Gly‐Asp‐containing Peptide, Inhibits Tumor Cell‐induced Platelet Aggregation

C. Teng, J. Sheu, Chao H. Lin, 1993, Japanese journal of cancer research : Gann.

Purification and Characterization of a Novel Metalloproteinase, Acurhagin, from Agkistrodon acutus Venom

Tur-Fu Huang, Wen-Jeng Wang, Tur‐Fu Huang, 2002, Thrombosis and Haemostasis.

Inhibitory effects of human alpha2-macroglobulin and mouse serum on the PSGL-1 and glycoprotein Ib proteolysis by a snake venom metalloproteinase, triflamp.

Wen-Bin Wu, Chun-Chieh Hsu, Y. Tseng, 2004, Toxicon : official journal of the International Society on Toxinology.

Triflamp (Trimeresurus flavoviridis)

Y. Tseng, Tur‐Fu Huang, 2013 .

Biological Activities of Snake Venom Metalloproteinases on Platelets, Neutrophils, Endothelial Cells, and Extracellular Matrices

Chun-Chieh Hsu, Tur‐Fu Huang, 2010 .

Effects of a snake venom metalloproteinase, triflamp, on platelet aggregation, platelet-neutrophil and neutrophilneutrophil interactions: involvement of platelet GPIbα. and neutrophil PSGL-1

Tur-Fu Huang, Y. Tseng, Chia-Jung Lee, 2003, Thrombosis and Haemostasis.

Measurement of Glycoprotein llb/llla Blockade by Flow Cytometry with Fluorescein Isothiocyanate-conjugated Crotavirin, a Member of Disintegrins

Chao-Zong Liu, Tur‐Fu Huang, Buo-Tsang Hur, 1996, Thrombosis and Haemostasis.

Analysis of Human Platelet Glycoprotein llb-llla by Fluorescein Isothiocyanate-Conjugated Disintegrins with Flow Cytometry

M. Shen, Chao-Zong Liu, Yi-Wen Wang, 1994, Thrombosis and Haemostasis.

Inhibition of neuropathic pain by a potent disintegrin—triflavin

W. Fu, D. Lu, Wei-Zen Sun, 2004, Neuroscience Letters.

The integrin α2β1 agonist, aggretin, promotes proliferation and migration of VSMC through NF‐kB translocation and PDGF production

Tur-Fu Huang, C. Chung, Kuan-Ting Lin, 2009, British journal of pharmacology.

The disintegrin, trimucrin, suppresses LPS-induced activation of phagocytes primarily through blockade of NF-κB and MAPK activation

C. Chung, Chun-Chieh Hsu, Tur‐Fu Huang, 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

Antiangiogenic mechanisms of PJ-8, a novel inhibitor of vascular endothelial growth factor receptor signaling.

S. Kuo, J. Lien, Shiu‐Wen Huang, 2012, Carcinogenesis.

Snake Venom Disintegrin Inhibits the Activation of Toll-Like Receptors and Alleviates Sepsis through Integrin alphaVbeta3 Blockade

W. Chuang, C. Chung, Chien-Hsin Chang, 2016, Scientific Reports.

A novel compound, NP-184, inhibits the vascular endothelial growth factor induced angiogenesis.

S. Kuo, C. Chung, Kuan-Ting Lin, 2010, European journal of pharmacology.

Activation of MMP-2, cleavage of matrix proteins, and adherens junctions during a snake venom metalloproteinase-induced endothelial cell apoptosis.

Wen-Bin Wu, Tur‐Fu Huang, 2003, Experimental cell research.

Disintegrin causes proteolysis of β-catenin and apoptosis of endothelial cells

Wen-Bin Wu, Tur‐Fu Huang, Hui‐Chin Peng, 2003 .

Cytokines Modulate Integrin αvβ3-Mediated Human Endothelial Cell Adhesion and Calcium Signaling☆

C. Yeh, Tur‐Fu Huang, Hui‐Chin Peng, 1999 .

Accutin, a New Disintegrin, Inhibits Angiogenesis In Vitro and In Vivo by Acting as Integrin vβ3 Antagonist and Inducing Apoptosis

C. Yeh, Tur‐Fu Huang, Hui‐Chin Peng, 1998 .

Integrin αvβ3 and phospholipase C regulate prostacyclin formation of endothelial cells caused by ancrod-generated fibrin

Mei‐Chi Chang, Rong-Sen Yang, Chao H. Lin, 1996 .

THE BIOLOGICAL ACTIVITIES OF DISINTEGRINS AND THEIR POSSIBLE APPLICATIONS

Tur-Fu Huang, Chao-Zong Liu, Tur‐Fu Huang, 1997 .

Characterization of Endothelial Cell Differential Attachment to Fibrin and Fibrinogen and Its Inhibition by Arg-Gly-Asp-Containing Peptides

Mei‐Chi Chang, Tur‐Fu Huang, Bih-Ru Wang, 1995, Thrombosis and Haemostasis.

Triflavin, an Arg-Gly-Asp-containing peptide, inhibits human cervical carcinoma (HeLa) cell-substratum adhesion through an RGD-dependent mechanism

Tur-Fu Huang, Hui-Chin Peng, J. Sheu, 1994, Peptides.

Inhibitory Effects of an Orally Active Thromboxane A2 Receptor Antagonist, nstpbp5185, on Atherosclerosis in ApoE-Deficient Mice

S. Kuo, J. Lien, Shiu‐Wen Huang, 2018, Thrombosis and Haemostasis.

Trimucytin, a collagen-like snake venom protein, activates platelets independent of I-domain within α2 subunit of α2β1 integrin

Ting-feng Wu, Guan-Ling Lin, Chao-Zong Liu, 2002 .

Atherosclerosis amelioration by allicin in raw garlic through gut microbiota and trimethylamine-N-oxide modulation

Chi-Tang Ho, C. Chung, H. Chuang, 2022, npj Biofilms and Microbiomes.

Rhodostomin, a disintegrin, inhibits adhesion of neutrophils to fibrinogen and attenuates superoxide production.

Y. Tseng, Tur‐Fu Huang, Hui‐Chin Peng, 2004 .

Primary structure and antiplatelet mechanism of a snake venom metalloproteinase, acurhagin, from Agkistrodon acutus venom.

Chun-Ho Shih, Tur‐Fu Huang, Wen‐Jeng Wang, 2005, Biochimie.

A novel 2‐aminobenzimidazole‐based compound Jzu 17 exhibits anti‐angiogenesis effects by targeting VEGFR‐2 signalling

M. Hsu, C. Chung, J. Lien, 2019, British Journal of Pharmacology.

Aggretin Venom Polypeptide as a Novel Anti-angiogenesis Agent by Targeting Integrin alpha2beta1

C. Chung, Chien-Hsin Chang, Chun-Chieh Hsu, 2017, Scientific Reports.

Inhibition of platelet aggregation by apigenin from apium graveolens

C. Teng, Tur‐Fu Huang, L. G. Lee, 1988 .

Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2

S. Hsieh, Tur‐Fu Huang, Pei-Shan Sung, 2019, Nature Communications.

4-Acetylantroquinonol B suppresses tumor growth and metastasis of hepatoma cells via blockade of translation-dependent signaling pathway and VEGF production.

C. Chung, Chien-Hsin Chang, Chun-Chieh Hsu, 2015, Journal of agricultural and food chemistry.

Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2

S. Hsieh, Tur‐Fu Huang, Pei-Shan Sung, 2019, Nature communications.

In Vivo Antithrombotic Effect of Triflavin, an Arg-Gly-Asp Containing Peptide on Platelet Plug Formation in Mesenteric Microvessels of Mice

J. Sheu, M. Yen, Seh-Huang Chao, 1994, Thrombosis and Haemostasis.

Rhodostomin, a Disintegrin, Inhibits Adhesion of Neutrophils to Fibrinogen and Attenuates Superoxide Production

Y. Tseng, Tur‐Fu Huang, Hui‐Chin Peng, 2004, Journal of Biomedical Science.

A selective serotonin reuptake inhibitor, citalopram, inhibits collagen-induced platelet aggregation and activation.

H. Lane, K. Su, Y. Tseng, 2010, Thrombosis research.

Triflamp, a snake venom metalloproteinase, reduces neutrophil-platelet adhesion through proteolysis of PSGL-1 but not glycoprotein Ibα

Chun-Chieh Hsu, Y. Tseng, Chia-Jung Lee, 2004, Thrombosis and Haemostasis.

Disintegrin causes proteolysis of beta-catenin and apoptosis of endothelial cells. Involvement of cell-cell and cell-ECM interactions in regulating cell viability.

Wen-Bin Wu, Tur‐Fu Huang, Hui‐Chin Peng, 2003, Experimental cell research.

Dicentrine, a natural vascular α1‐adrenoceptor antagonist, isolated from Lindera megaphylla

Yu-Ling Huang, C. Teng, F. Ko, 1991 .

Aggretin, a snake venom-derived endothelial integrin alpha 2 beta 1 agonist, induces angiogenesis via expression of vascular endothelial growth factor.

C. Chung, Wen-Bin Wu, Tur‐Fu Huang, 2004, Blood.

A Novel Tetrameric Venom Protein, Agglucetin from Agkistrodon acutus , Acts as a Glycoprotein Ib Agonist

Tur‐Fu Huang, Wen‐Jeng Wang, 2001, Thrombosis and Haemostasis.

Inhibition of Platelet Thromboxane Formation and Phosphoinositides Breakdown by Osthole from Angelica pubescens

C. Teng, F. Ko, Tur‐Fu Huang, 1989, Thrombosis and Haemostasis.

Bp5250 inhibits vascular endothelial growth factor-induced angiogenesis and HIF-1α expression on endothelial cells

S. Kuo, C. Chung, Kuan-Ting Lin, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasis

C. Tseng, P. Hsieh, K. Chong, 2015, Oncotarget.