Zhi-hong Yu

发表

Anticancer effect of jinlongshe granules on in situ-transplanted human MKN-45 gastric cancer in nude mice and xenografted sarcoma 180 in Kunming mice and its mechanism.

Jun Shi, P. Wei, Ling Xu, 2006, World journal of gastroenterology.

[Effects of jinlongshe granules on apoptosis of MKN-45 human gastric cancer cells orthotopically transplanted in nude mice].

Yan Xiao, Hui-Ming Lin, Jun Shi, 2006, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

[D-limonene induces apoptosis of gastric cancer cells].

Bing Feng, L. Zhan, Zhi-hong Yu, 2003, Zhonghua zhong liu za zhi [Chinese journal of oncology].

Therapeutic Potential of Targeting the Oncogenic SHP2 Phosphatase

C. Wells, R. Chan, Zhon-Yin Zhang, 2014, Journal of medicinal chemistry.

Therapeutic Targeting of Oncogenic Tyrosine Phosphatases.

Zhon-Yin Zhang, Yunpeng Bai, Qinglin Li, 2017, Cancer research.

Changes of hMSH2 and hMLH1 Expression in Nasopharyngeal carcinoma cells after X-radiation

Min Liu, Jing Fu, Yan Wang, 2005 .

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.

Jie Xu, Zhon-Yin Zhang, Zhong-Yin Zhang, 2013, Journal of medicinal chemistry.

Postcoital administration of asoprisnil inhibited embryo implantation and disturbed ultrastructure of endometrium in implantation window in mice

J. Qiu, P. Su, Zhi-hong Yu, 2013, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis.

Zhon-Yin Zhang, Yunpeng Bai, A. Gunawan, 2014, MedChemComm.

[Effects of Rhizoma kaempferiae volatile oil on tumor growth and cell cycle of MKN-45 human gastric cancer cells orthotopically transplanted in nude mice].

Yan Xiao, Hui-Ming Lin, P. Wei, 2006, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

OB glue paste technique for establishing nude mouse human gastric cancer orthotopic transplantation models.

Yan Xiao, Hui-Ming Lin, S. Zhang, 2008, World journal of gastroenterology.

Protein tyrosine phosphatases as potential therapeutic targets

Ruo-yu Zhang, Zhon-Yin Zhang, Rong-jun He, 2014, Acta Pharmacologica Sinica.

MicroRNA-181a-5p Promotes Osteosarcoma Progression via PTEN/AKT Pathway

Jun Guo, Liang Xiao, Wei Qian, 2022, Analytical cellular pathology.

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation

Jidong Zhu, Jingjing Xie, Dan Li, 2020, Cell.

Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.

Zhon-Yin Zhang, Zhi-hong Yu, 2017, Chemical reviews.

SHP2 phosphatase as a novel therapeutic target for melanoma treatment

S. Zhang, Jingwu Xie, Zhon-Yin Zhang, 2016, Oncotarget.

Molecular Basis of Gain-of-Function LEOPARD Syndrome-Associated SHP2 Mutations

Zhon-Yin Zhang, S. Zhang, Li Wu, 2014, Biochemistry.

Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.

Zhon-Yin Zhang, Li Wu, Sijiu Liu, 2011, Bioorganic & medicinal chemistry letters.

Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations*

Shenmin Zhang, Jie Xu, Zhon-Yin Zhang, 2013, The Journal of Biological Chemistry.

Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP 2 Mutations

Jie Xu, Ruoyu Zhang, S. Zhang, 2013 .

Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors.

Zhon-Yin Zhang, Yantao He, R. He, 2012, Bioorganic & medicinal chemistry.

Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2

S. Zhang, Zhon-Yin Zhang, Li Wu, 2020, The Journal of Biological Chemistry.

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.

Jun O. Liu, C. Wells, J. Shim, 2015, ACS medicinal chemistry letters.

Antitumor Activity of a Recombinant Soluble Ectodomain of Mutant Human Fibroblast Growth Factor Receptor-2 IIIc

Ju Wang, Ding-ding Wang, Xue-ting Liu, 2011, Molecular Cancer Therapeutics.

Gowth Factor Recptor-2 IIIc

Ju Wang, Ding-ding Wang, Xue-ting Liu, 2011 .

A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.

J. Dixon, Zhon-Yin Zhang, Yan Zhang, 2015, Bioorganic & medicinal chemistry.

[Methylation of hMLH1 gene promoter in gastric carcinoma with microsatellite instability].

Min Liu, Xianzhe Shi, Yan Wang, 2005, Ai zheng = Aizheng = Chinese journal of cancer.

Inhibition of Low Molecular Weight Protein Tyrosine Phosphatase by an Induced-Fit Mechanism.

Zhon-Yin Zhang, Jifeng Wang, R. He, 2016, Journal of medicinal chemistry.

Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase.

Zhon-Yin Zhang, Yunpeng Bai, Lifan Zeng, 2016, Cancer research.

A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.

David R. Jones, X. Dong, Zhon-Yin Zhang, 2012, Journal of the American Chemical Society.

Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate*

Zhon-Yin Zhang, Y. Takagi, S. Zhang, 2011, The Journal of Biological Chemistry.

Saikosaponin D inhibits proliferation of human osteosarcoma cells via the p53 signaling pathway.

Zhi-hong Yu, Chen Sun, Xiao Guo, 2018, Experimental and therapeutic medicine.

Mutant soluble ectodomain of fibroblast growth factor receptor-2 IIIc attenuates bleomycin-induced pulmonary fibrosis in mice.

Ju Wang, Ding-ding Wang, Shui-lian He, 2012, Biological & pharmaceutical bulletin.

Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis.

Zhon-Yin Zhang, A. Gunawan, R. He, 2015, ACS medicinal chemistry letters.

Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.

N. Noinaj, Zhon-Yin Zhang, M. Michael, 2022, Journal of medicinal chemistry.

Discovery and Evaluation of PRL Trimer Disruptors for Novel Anticancer Agents.

Zhon-Yin Zhang, Yunpeng Bai, Zhi-hong Yu, 2016, Methods in molecular biology.

Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.

Zhon-Yin Zhang, Zhi-hong Yu, 2017, Chemical reviews.

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.

Jun O. Liu, C. Wells, J. Shim, 2015, ACS medicinal chemistry letters.