Na-Oh Yunn

发表

An aptamer agonist of the insulin receptor acts as a positive or negative allosteric modulator, depending on its concentration

S. Ryu, S. Bae, Eun Ju Oh, 2022, Experimental & molecular medicine.

PI3K-C2 a Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation

Sung Ho Ryu, T. Pereira, S. Ryu, 2017 .

Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures

S. Ryu, Yunje Cho, Jeongeun Noh, 2022, Nature Communications.

Stepwise autophosphorylation regulates biased agonism of the insulin receptor

S. Ryu, J. Noh, Na-Oh Yunn, 2019, bioRxiv.

Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1

Yun‐Sil Lee, S. Ryu, Yunje Cho, 2022, Nature Communications.

Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation

F. Bäckhed, P. Nilsson, S. Ryu, 2020, Cell metabolism.

Mechanistic understanding of insulin receptor modulation: Implications for the development of anti-diabetic drugs.

S. Ryu, Jaeyoon Kim, P. Berggren, 2017, Pharmacology & therapeutics.

Formation of cellular close-ended tunneling nanotubes through mechanical deformation

A. Kolomeisky, Hyung-Bae Kwon, Jae-Hyung Jeon, 2022, Science advances.

Agonistic aptamer to the insulin receptor leads to biased signaling and functional selectivity through allosteric modulation

S. Jang, S. Ryu, A. Koh, 2015, Nucleic acids research.

Aptamer-based single-molecule imaging of insulin receptors in living cells

Minhyeok Chang, Mijin Kwon, Sooran Kim, 2013, Journal of biomedical optics.

A hotspot for enhancing insulin receptor activation revealed by a conformation-specific allosteric aptamer

S. Ryu, Jeongeun Noh, Na-Oh Yunn, 2021, Nucleic acids research.

A stepwise activation model for the insulin receptor

Sung Ho Ryu, Na-Oh Yunn, Junhong Kim, 2023, Experimental & molecular medicine.