Masahiro Konishi

发表

A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

T. Kadowaki, N. Kubota, T. Kubota, 2021, Communications biology.

A Novel Xanthene Derivative, DS20060511, Attenuates Glucose Intolerance by Inducing Skeletal Muscle-specific GLUT4 Translocation in Diabetic Mice

T. Kadowaki, N. Kubota, T. Kubota, 2020 .

Discovery of novel pyridazine derivatives as glucose transporter type 4 (GLUT4) translocation activators.

Yoshiyuki Kobayashi, T. Tsuji, Jun Tanaka, 2019, Bioorganic & medicinal chemistry letters.

Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl)piperidin-1-yl]pyridazine-3-carboxylic acid (2-hydroxy-2-pyridin-3-ylethyl)amide and its plasma triglyceride-lowering effects in Zucker fatty rats.

J. Ohsumi, Y. Uto, N. Watanabe, 2010, Bioorganic & medicinal chemistry letters.

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation.

M. Yamada, Y. Uto, N. Watanabe, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1'-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-3,4-dihydrospiro[chromene-2,4'-piperidine] analogs.

M. Yamada, J. Ohsumi, Y. Uto, 2010, European journal of medicinal chemistry.

Novel spiropiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 1'-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-5-(trifluoromethyl)-3,4-dihydrospiro[chromene-2,4'-piperidine].

M. Yamada, J. Ohsumi, Y. Uto, 2010, Bioorganic & medicinal chemistry letters.

A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

N. Kubota, T. Kubota, M. Tsutsui, 2021, Communications Biology.

Synthesis and biological evaluation of novel imidazol-1-ylacetic acid derivatives as non-brain penetrant bombesin receptor subtype-3 (BRS-3) agonists.

Y. Nagai, Yasuyuki Abe, K. Shimada, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach.

Y. Nagai, Yasuyuki Abe, K. Shimada, 2015, Bioorganic & medicinal chemistry.

Discovery of novel chiral diazepines as bombesin receptor subtype-3 (BRS-3) agonists with low brain penetration.

K. Shimada, Kazuhiro Yoshida, Hisashi Takahashi, 2014, Bioorganic & medicinal chemistry letters.