Hong Chen

发表

Single- and Multiple-Dose Pharmacokinetics and Tolerability of Limaprost in Healthy Chinese Subjects

Qi Zhang, Xiaojiao Li, Hong Zhang, 2015, Clinical Drug Investigation.

Phase I Trial to Evaluate the Tolerance, Pharmacokinetics and Efficacy of the Broad-Spectrum ErbB Family Inhibitor Larotinib Mesylate in Patients With Advanced Solid Tumors

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2020, Frontiers in Pharmacology.

Clinical evaluation of efficacy, tolerability and pharmacokinetics of yimitasvir phosphate in patients infected with hepatitis C virus

J. Niu, Xiaojiao Li, Hong Zhang, 2018, The Journal of pharmacy and pharmacology.

Pharmacokinetic Profile of a Generic Formulation of Sofosbuvir and Its Metabolite GS‐331007 in Healthy Chinese Subjects

J. Niu, Xiaojiao Li, Hong Zhang, 2019, Clinical pharmacology in drug development.

Pharmacokinetics, Safety, and Tolerability of the Direct-acting Hepatitis C Antiviral Sofosbuvir in HealthyChineseSubjects.

J. Niu, D. Brainard, Xiaojiao Li, 2018, Clinical therapeutics.

Single-dose pharmacokinetic properties, bioavailability, and tolerability of two lamivudine 100-mg tablet formulations: a randomized crossover study in healthy Chinese male subjects.

Haiyan Chen, Qi Zhang, Xiaojiao Li, 2013, Clinical therapeutics.

Antiviral Activity and Pharmacokinetics of the Hepatitis B Virus (HBV) Capsid Assembly Modulator GLS4 in Patients With Chronic HBV Infection

J. Niu, Xiaojiao Li, Hong Zhang, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers

J. Niu, D. Zhong, Wei Li, 2018, Front. Pharmacol..

Pharmacokinetics, Pharmacodynamics, and Tolerability of Single and Multiple Doses of Trandolapril, an Effective Angiotensin-Converting Enzyme Inhibitor, in Healthy Chinese Subjects

Qi Zhang, Xiaojiao Li, Hong Zhang, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

Pharmacokinetics, safety, and tolerability of TQC3564, a novel CRTh2 receptor antagonist: report of the first-in-human single- and multiple-dose escalation trials in healthy Chinese subjects

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2022, Expert opinion on investigational drugs.

Safety, pharmacokinetics and pharmacodynamics of a novel γ-aminobutyric acid (GABA) receptor potentiator, HSK3486, in Chinese patients with hepatic impairment

Shiping Ma, Chengluan Xuan, Xiaojiao Li, 2022, Annals of medicine.

A Phase I Clinical Study Comparing the Tolerance, Immunogenicity, and Pharmacokinetics of Proposed Biosimilar BAT1806 and Reference Tocilizumab in Healthy Chinese Men

X. Yang, Xiaojiao Li, Hong Zhang, 2021, Frontiers in Pharmacology.

A phase I study of fluzoparib tablet formulation, an oral PARP inhibitor: effect of food on the pharmacokinetics and metabolism after oral dosing in healthy Chinese volunteers

Xiaojiao Li, Yanhua Ding, Min Wu, 2021, Expert opinion on drug metabolism & toxicology.

Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of the QX002N anti-IL-17 Monoclonal Antibody: A Phase I, Randomized, Double-Blind, Single Ascending Dose Study in Healthy Chinese Volunteers

Hong Zhang, Yanhua Ding, Min Fang, 2022, Frontiers in Pharmacology.

Changing Technologies of RNA Sequencing and Their Applications in Clinical Oncology

Ye Wang, Bin Liu, Xin Zhou, 2020, Frontiers in Oncology.

Safety, pharmacokinetics and pharmacodynamics of TQ-A3334, an oral toll-like receptor 7 agonist in healthy individuals

J. Niu, Xiaojiao Li, Hong Zhang, 2021, Expert opinion on investigational drugs.

The effect of a single escalating dose of long-acting recombinant human follicle-stimulating hormone Fc fusion protein (KN015) on healthy, pituitary-suppressed women: first-in-human and randomized study on its pharmacokinetics, pharmacodynamics, and tolerability

Ting Xu, Xiaojiao Li, Hong Zhang, 2022, Expert opinion on investigational drugs.

Safety, pharmacokinetics and pharmacogenetics of a single ascending dose of pradefovir, a novel liver-targeting, anti-hepatitis B virus drug, in healthy Chinese subjects

J. Niu, Xiaojiao Li, Hong Zhang, 2017, Hepatology International.

Randomised clinical trial: safety, efficacy and pharmacokinetics of HS‐10234 versus tenofovir for the treatment of chronic hepatitis B infection

J. Niu, Xiaojiao Li, Hong Zhang, 2020, Alimentary Pharmacology and Therapeutics.

Tolerability, pharmacokinetics and antiviral activity of rHSA/IFN&agr;2a for the treatment of chronic hepatitis B infection

J. Niu, Xiaojiao Li, Hong Zhang, 2017, British journal of clinical pharmacology.

First-In-Human Study on Pharmacokinetics, Safety, and Tolerability of Single and Multiple Escalating Doses of Hepenofovir, a Novel Hepatic Targeting Prodrug of Tenofovir in Healthy Chinese Subjects

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2022, Frontiers in Pharmacology.

Safety, efficacy, and pharmacokinetics of pradefovir for the treatment of chronic hepatitis B infection.

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2019, Antiviral research.

Tolerability and efficacy of pegylated consensus interferon-α in the treatment of chronic hepatitis C

B. Liu, Qi Zhang, Hong Zhang, 2016, Experimental and therapeutic medicine.

FDA-Approved and Emerging Next Generation Predictive Biomarkers for Immune Checkpoint Inhibitors in Cancer Patients

A. Buzdin, Xinmin Li, Hui-Hua Chang, 2021, Frontiers in Oncology.

Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial.

Kaixian Chen, Hualiang Jiang, Dalei Wu, 2022, Cell metabolism.

Clinical Next Generation Sequencing for Precision Medicine in Cancer

Ling Dong, Xinmin Li, Xinmin Li, 2015, Current genomics.

Bioequivalence and Pharmacokinetic Profiles of Agomelatine 25-mg Tablets in Healthy Chinese Subjects: A Four-Way Replicate Crossover Study Demonstrating High Intra- and Inter-Individual Variations.

Y. Qiao, J. Niu, Hong Zhang, 2017, Chemical & pharmaceutical bulletin.

An Evaluation of the Pharmacokinetics, Safety, and Tolerability of Aclidinium/Formoterol Fixed-Dose Combination Administered in Chinese Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease

E. Molins, Hong Zhang, Yanhua Ding, 2022, Drugs in R&D.

A Phase I Study on the Pharmacokinetics and Pharmacodynamics of DJT1116PG, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter Type 2, in Healthy Individuals at Steady State.

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2020, Clinical therapeutics.

Pharmacokinetics and pharmacodynamics of rongliflozin, a novel selective inhibitor of sodium‐glucose co‐transporter‐2, in people with type 2 diabetes mellitus

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2020, Diabetes, obesity & metabolism.

Safety and pharmacokinetics of a new biosimilar trastuzumab (HL02): a Phase I bioequivalence study in healthy Chinese men

Xiaojiao Li, Hong Zhang, Haijing Wei, 2021, Expert Opinion on Biological Therapy.

Pharmacokinetics and safety profiles of novel diethylstilbestrol orally dissolving film in comparison with diethylstilbestrol capsules in healthy Chinese male subjects.

Qi Zhang, Xiaojiao Li, Hong Zhang, 2014, International journal of clinical pharmacology and therapeutics.

Safety, tolerability, pharmacokinetics, and antiviral activity of the novel core protein allosteric modulator ZM-H1505R (Canocapavir) in chronic hepatitis B patients: a randomized multiple-dose escalation trial

Huanming Chen, Hui Lu, J. Niu, 2023, BMC Medicine.

Pharmacokinetics, Pharmacodynamics, and Tolerability of Single and Multiple Doses of Trandolapril, an Effective Angiotensin-Converting Enzyme Inhibitor, in Healthy Chinese Subjects

Qi Zhang, Xiaojiao Li, Hong Zhang, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

Bioequivalence of Sarpogrelate in Healthy Chinese Subjects Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Investigation by a Reference‐Scaled Average Bioequivalence Approach

Bin Liu, Yanhua Ding, Y. Ding, 2018, Clinical pharmacology in drug development.

Xiaojiao Li, Hong Zhang, Yanhua Ding, 2021, Frontiers in Pharmacology.

Clinical Evaluation of the Tolerability and Pharmacokinetics of Azilsartan, a Potent Angiotensin Receptor Blocker, in Healthy Chinese Subjects

Yingjie Guo, Xiaojiao Li, Hong Zhang, 2020, Clinical pharmacology in drug development.

Safety, tolerability, pharmacokinetics and pharmacodynamics of a novel farnesoid X receptor (FXR) agonist-TQA3526 in healthy Chinese volunteers: a double-blind, randomized, placebo-controlled, dose-escalation, food effect phase I study

Hong Zhang, Yanhua Ding, Cuiyun Li, 2023, Annals of medicine.